ID A0A1I8NMK1_STOCA Unreviewed; 766 AA.
AC A0A1I8NMK1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Regulator of G-protein signaling loco {ECO:0008006|Google:ProtNLM};
GN Name=106088804 {ECO:0000313|EnsemblMetazoa:SCAU000351-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU000351-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU000351-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU000351-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013109947.1; XM_013254493.1.
DR AlphaFoldDB; A0A1I8NMK1; -.
DR STRING; 35570.A0A1I8NMK1; -.
DR EnsemblMetazoa; SCAU000351-RA; SCAU000351-PA; SCAU000351.
DR GeneID; 106088804; -.
DR KEGG; scac:106088804; -.
DR VEuPathDB; VectorBase:SCAU000351; -.
DR OrthoDB; 22856at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01817; RBD1_RGS12_like; 1.
DR CDD; cd17067; RBD2_RGS12_like; 1.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR046995; RGS10/12/14-like.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45945; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR PANTHER; PTHR45945:SF3; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR Pfam; PF02196; RBD; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00455; RBD; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50898; RBD; 2.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468}.
FT DOMAIN 95..211
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 329..399
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT DOMAIN 400..470
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT REGION 242..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 684..766
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..727
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 766 AA; 85886 MW; E7A4B7DBCE334F7C CRC64;
MMSMTRIFSN STSSFRRVWE QSSLRSPRSD KYTSKHCGKQ CSTSMIASEN DVFLAATGKD
ATSTKRHQLL PMRNTHSEKM TPPTKTPRVS AWAISFEHLL EDTAGLATFA AFLKMEFSAE
NIYFWTSCER YKNTENLLDR QIQAKHIYGQ YLSSNSSEPV NLDSQTRNLS EEALQQADKD
LLVKAQKQIF HLMKFDSYQR FIRSELYKNC LNAEEKNLTL PYGDDNLDDM LKTNFSQCAS
PKLKKSASNA EDRRRKILLP WHRKTRSKSR DRMDVACDES HETSNGSSPA LNTLVVPSTK
MTSAKSTESC DTQRSSLPSS LKSINSTCSL CRVKFSDDAT TIVQIKPNET VGQLVERLLE
KRGLRYRLYE VLLKSHNKSI DPQTSSQTIA GEEVEIEQRV TFKLYLPDPK AISVKSKPKK
YLHEVVMPIL QKYNYDMDSV DVLRGDTMET LDLAKLVTTV DDQRLYVVLR PTTLMHSASN
KKLKNGAADY QNDSISLHYI KSKELASEFI ARNSKSNIKS SSVGSSSEGN LIEATNIIFE
NIIKEKTQPG KQSQSIDQYS LKSDEFGSEI SVYYDTLNNS KGSSTNLRPR IKTAIKPHSS
EGNIAAGDFN KPIIAKLKAG VKLQVTERVA EKQDELLISL KSRLDNPPSS VMNANELLDN
ARNKDNQNDT ALVLRHIRST LSPINKTYSP TSLNHESVPS PTLDKPSSLT NRTSLIRNSL
LSNSEETSNH SETDETSAAC KGPPPLPPKP KVLPTKPSNW GATNSD
//
