ID A0A1I8NNS2_STOCA Unreviewed; 584 AA.
AC A0A1I8NNS2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=KIND domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=106081112 {ECO:0000313|EnsemblMetazoa:SCAU000695-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU000695-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU000695-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU000695-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004413};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004413};
CC Cytoplasmic side {ECO:0000256|ARBA:ARBA00004413}. Cytoplasm,
CC cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Cytoplasmic vesicle
CC membrane {ECO:0000256|ARBA:ARBA00004180}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004180}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004180}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the spire family.
CC {ECO:0000256|ARBA:ARBA00010956}.
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DR RefSeq; XP_013098307.1; XM_013242853.1.
DR RefSeq; XP_013098308.1; XM_013242854.1.
DR RefSeq; XP_013098310.1; XM_013242856.1.
DR AlphaFoldDB; A0A1I8NNS2; -.
DR STRING; 35570.A0A1I8NNS2; -.
DR EnsemblMetazoa; SCAU000695-RA; SCAU000695-PA; SCAU000695.
DR EnsemblMetazoa; SCAU000695-RC; SCAU000695-PC; SCAU000695.
DR EnsemblMetazoa; SCAU000695-RD; SCAU000695-PD; SCAU000695.
DR KEGG; scac:106081112; -.
DR VEuPathDB; VectorBase:SCAU000695; -.
DR OrthoDB; 2900844at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0045010; P:actin nucleation; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd22068; WH2_DmSpire_r3-like; 1.
DR CDD; cd22078; WH2_Spire1_r2-like; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011019; KIND_dom.
DR InterPro; IPR029901; Spire.
DR InterPro; IPR003124; WH2_dom.
DR PANTHER; PTHR21345:SF3; PROTEIN SPIRE; 1.
DR PANTHER; PTHR21345; SPIRE; 1.
DR Pfam; PF16474; KIND; 1.
DR Pfam; PF02205; WH2; 1.
DR SMART; SM00750; KIND; 1.
DR SMART; SM00246; WH2; 3.
DR PROSITE; PS51377; KIND; 1.
DR PROSITE; PS51082; WH2; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 185..395
FT /note="KIND"
FT /evidence="ECO:0000259|PROSITE:PS51377"
FT DOMAIN 538..555
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 584 AA; 66706 MW; 4ABB67BAD8644643 CRC64;
MTTEIQENFG DPIKPQQQSN ISQNGKDQTV DEGGGGELEA GKYPPSTFVT PEQNQQMLNT
TTNDAGAHEC SSSNSNNNNN DSKIMNCSSN SSNNLAAKVI YGSRSNGNIK CPKLLQTSDG
EEGFLSTSPD SANEELLLSK SGGELEPNEI TTNSNTKNQL SICSVSTLPL PPPSIYNCSN
PKDCVNVKNI LESFKAPLSE EQAWALLYQF ISLYRRVAAS VKRYVFNELE IPECMDNMSL
HRDGSVHCSW SELERNKRQQ AIQQREQAQE ADQSGDFNHA QHIASHKKVL RKIAVVVYNA
LDYNLHEDEQ CQMSQELEEL ITHMTVDDDE TDDECIDDCI DEGIDEGYKR WDDDHDETKE
FDFVLEACKN HIKPTVPEEH YKAVCRALVT ETLELRIFLQ QVLNNGADNL HLKADSQASQ
QELAKFDFND WQELQIWRAI QARFWVQVID ELRRGVRLKK ANYERAPIEY ELTPYEILME
DIRSRKYQLR KVMVNGDIPP RVKKDAHALI LDFIRSRPPL KKASERQLPP PIKRTPSPRE
QLMDSIRKGR TLKHIPSPTL PRLKDRYSIY EYQQASKYSY CQLI
//
