ID A0A1I8NT63_STOCA Unreviewed; 522 AA.
AC A0A1I8NT63;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 28-JUN-2023, entry version 28.
DE RecName: Full=SLC41A/MgtE integral membrane domain-containing protein {ECO:0000259|Pfam:PF01769};
GN Name=106087816 {ECO:0000313|EnsemblMetazoa:SCAU001790-PC};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU001790-PC, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU001790-PC}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU001790-PC};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC {ECO:0000256|ARBA:ARBA00009749}.
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DR RefSeq; XP_013108443.1; XM_013252989.1.
DR AlphaFoldDB; A0A1I8NT63; -.
DR EnsemblMetazoa; SCAU001790-RC; SCAU001790-PC; SCAU001790.
DR GeneID; 106087816; -.
DR VEuPathDB; VectorBase:SCAU001790; -.
DR OrthoDB; 5124745at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 2.
DR InterPro; IPR006667; SLC41_membr_dom.
DR InterPro; IPR036739; SLC41_membr_dom_sf.
DR InterPro; IPR045349; SLC41A1-3.
DR PANTHER; PTHR16228:SF26; AGAP000663-PA; 1.
DR PANTHER; PTHR16228; DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41; 1.
DR Pfam; PF01769; MgtE; 2.
DR SUPFAM; SSF161093; MgtE membrane domain-like; 2.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 104..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 225..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..284
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 290..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 325..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 484..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 145..278
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT DOMAIN 357..499
FT /note="SLC41A/MgtE integral membrane"
FT /evidence="ECO:0000259|Pfam:PF01769"
FT REGION 47..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 522 AA; 55662 MW; 014A07715A332C4F CRC64;
MNGFLGIRLS RGYIKLPECE EDTDNDKLSG LPHSTTGSLS SIITTSIASS EPDPGAGGGG
GGGGGGGGNG GGGSAGNGHD GQNSADEKMA LNRPGIKQEK WTTILLQVSI PFFLAGIGTI
GAGIILGRVE KWRVFKSVSE LFILVPALLG LKGNLDMCLA SRLSTQVNLG NMTSRQEVVR
MIVGNIALVQ VQATVASFLV AMFAIGVGAA MDGNFEFEHV MLLTASAMFT ATSSCFVLDF
VLVAVILLSQ KYRLNPDNLA TPLAASIGDV VSISLLSFIA SLLFDHIKTH LWITFVVVAC
YLVLLPMWVT VVLKNKYTRP VLKSGWVPVL SALCISGLGG LVLDAAVEIF NGFVVFQPII
NGIGGNLVSV QASKISTMLH QSSIIGIIPP HTKIFEWPWK ALFKGVPYAK TARLLICMSI
PGNILFIFAA DYIHMSQSTV TFAFVMSYLV ASLIQVMLLL YIAHIIVHAM WKWKIDPDNS
SIPYLTALGD LLGSSLLALA FIFLLSINKE YGADYDALDA SN
//
