ID A0A1I8NVV4_STOCA Unreviewed; 1142 AA.
AC A0A1I8NVV4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=BK channel {ECO:0000256|ARBA:ARBA00029579};
GN Name=106083984 {ECO:0000313|EnsemblMetazoa:SCAU002490-PAG};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU002490-PAG, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU002490-PAG}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU002490-PAG};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR RefSeq; XP_013103068.1; XM_013247614.1.
DR AlphaFoldDB; A0A1I8NVV4; -.
DR EnsemblMetazoa; SCAU002490-RAG; SCAU002490-PAG; SCAU002490.
DR GeneID; 106083984; -.
DR VEuPathDB; VectorBase:SCAU002490; -.
DR OrthoDB; 2902976at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005261; F:monoatomic cation channel activity; IEA:UniProt.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR048735; Slowpoke-like_C.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF33; CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF21014; Slowpoke_C; 1.
DR PRINTS; PR01449; BKCHANNELA.
DR PRINTS; PR00169; KCHANNEL.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 282..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..326
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 124..339
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 491..579
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT DOMAIN 983..1102
FT /note="Ca2+-activated K+ channel Slowpoke-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21014"
FT REGION 685..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..719
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1120..1142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1142 AA; 126865 MW; 08FAF2CEAD9CF6AF CRC64;
MANLTDLDQA VAGMSGCDQS TVESLAEDPT GSPFEVDDCL KVRKYYCFLL SSIFTFLAGF
LIVLLWRAFA FICCRKEPEL GPNDPKQKEQ KASRNKQEFE GTFMTEAKDW AGELISGQTT
TGRILVVLVF ILSIASLIIY FVDASNEEVE RCQPWSTNIT QQIDLAFNIF FMVYFFIRFI
AASDKLWFML EMYSFVDYFT IPPSFVSIYL DRTWIGLRFL RALRLMTVPD ILQYLNVLKT
SSSIRLAQLV SIFISVWLTA AGIIHLLENS GDPLDFDNAH RLSYWTCVYF LIVTMSTVGY
GDVYCETVLG RTFLVFFLLV GLAMFASSIP EIIELVGSGN KYGGELKREH GKRHIVVCGH
ITYESVSHFL KDFLHEDRED VDVEVVFLHR KPPDLELEGL FKRHFTTVEF FQGTIMNPID
LQRVKVHEAD ACLVLANKYC QDPDAEDAAN IMRVISIKNY SDDIRVIIQL MQYHNKAYLL
NIPSWDWKQG DDVICLAELK LGFIAQSCLA PGFSTMMANL FAMRSFKTSP DTQAWQNDYL
QGTGCEMYTE TLSPSFTGMT FPQASELCFS KLKLLLLAIE IKGNEDGADS KISINPRGAK
IQANTQGFFI AQSADEVKRA WFYCKACHED IKDETLIKKC KCKNFLNRHN RRPNGSTSMG
PGNGTTALHS SAAVKQVNKV KPTVNRQLEG GQVMSPSQYN RPTSRSTGTG SQNANGGSVS
LPAGIADDQS KDFDFEKTEM KYDSTGMFHW SPAKSLEDCI LDRNQAAMTV LNGHVVVCLF
ADPDSPLIGL RNLVMPLRAS NFHYHELKHV VIVGSVDYIR REWKMLQNLP KISVLNGSPL
SRADLRAVNV NLCDMCCILS AKVPSNDDPT LADKEAILAS LNIKAMTFDD TIGVLSQRGP
EFDNLTAAAG SPIVLQRRGS VYGANVPMIT ELVNDSNVQF LDQDDDDDPD TELYLTQPFA
CGTAFAVSVL DSLMSTTYFN QNALTLIRSL ITGGATPELE LILAEGAGLR GGYSTPESLS
NRDRCRVGQI SLYDGPLAQF GECGKYGDLF VAALKSYGML CIGLYRFRDT SSSCDASSKR
YVITNPPDDF SLLPTDQVFV LMQFDPGLEY KPPAVRAPTG GRNANTQGSG VGGGGSNKDD
NS
//
