ID A0A1I8NXH8_STOCA Unreviewed; 600 AA.
AC A0A1I8NXH8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=2-phosphoxylose phosphatase 1 {ECO:0000256|ARBA:ARBA00040357};
DE AltName: Full=Acid phosphatase-like protein 2 {ECO:0000256|ARBA:ARBA00041499};
GN Name=106089696 {ECO:0000313|EnsemblMetazoa:SCAU002919-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU002919-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU002919-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU002919-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-O-[beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-
CC beta-D-2-O-P-Xyl]-L-seryl-[protein] + H2O = 3-O-(beta-D-GlcA-(1->3)-
CC beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] +
CC phosphate; Xref=Rhea:RHEA:56512, Rhea:RHEA-COMP:12573, Rhea:RHEA-
CC COMP:14559, ChEBI:CHEBI:15377, ChEBI:CHEBI:43474, ChEBI:CHEBI:132093,
CC ChEBI:CHEBI:140495; Evidence={ECO:0000256|ARBA:ARBA00036311};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032};
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004323}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004323}. Membrane
CC {ECO:0000256|ARBA:ARBA00004606}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC {ECO:0000256|ARBA:ARBA00005375}.
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DR RefSeq; XP_013111102.1; XM_013255648.1.
DR AlphaFoldDB; A0A1I8NXH8; -.
DR STRING; 35570.A0A1I8NXH8; -.
DR EnsemblMetazoa; SCAU002919-RA; SCAU002919-PA; SCAU002919.
DR GeneID; 106089696; -.
DR KEGG; scac:106089696; -.
DR VEuPathDB; VectorBase:SCAU002919; -.
DR OrthoDB; 3403603at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR033379; Acid_Pase_AS.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR PANTHER; PTHR11567:SF125; 2-PHOSPHOXYLOSE PHOSPHATASE 1; 1.
DR PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Signal-anchor {ECO:0000256|ARBA:ARBA00022968};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 600 AA; 67305 MW; 6AAAB03E7E80E122 CRC64;
MLLKELIRFS TQHRTLYCYM ILSIWIFLLI AGMYKYIGRN TNSLSYILNG NSHMYGGASI
TATPSMDSNN FAKYKTRCTP LSHINRLDDG GILDGWKLQG VLMIIRHGDR GPMSHVRSVP
HLDCGITGDN LVNKYRSFLY NTTSVSGSNH MYWNKVGPFH GFPLLPLTEK ECLLGQLTYK
GIAQLLHVGE ILHQIYAHPL GLWIRQAATN QYGRSVANST PYSTLLNSDE VVVYTTRVRR
TFQSALALLY TFLPTDKWLA LNVKESHSIA FCFTDCVCQK ADALRKELLK VQKRGLAKQP
MVTQVMHWIG NQLLQHTPNG INDPNEVVDA MLTVMCHDAP WPCRRNVNGT ERMAVSTKAN
DLDLNDVINI DQDDVLAGGV GGAGMVNGVD ALGAVNAVGD VNSNAIQLQT ANEEVSTSAN
NEACIEASHV STMMSFSNWQ STREVHHAFY KRIGLMRAYG MIRHIVSYML RMISGDRTKF
VLYSGHDWTL QYLTAALGIQ TDNTFIAYAA RLAFEVYKSE AHTDYYFRVV YDGHDVTQQI
DFCEGGKSLR VTRDSRGNKA DLCPIENIIR FLHEDYFGPL NATNFKDACI MTANPKGNEF
//
