ID A0A1I8P0N3_STOCA Unreviewed; 1161 AA.
AC A0A1I8P0N3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Nephrin {ECO:0008006|Google:ProtNLM};
GN Name=106088805 {ECO:0000313|EnsemblMetazoa:SCAU003754-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU003754-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU003754-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU003754-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013109950.1; XM_013254496.1.
DR AlphaFoldDB; A0A1I8P0N3; -.
DR STRING; 35570.A0A1I8P0N3; -.
DR EnsemblMetazoa; SCAU003754-RA; SCAU003754-PA; SCAU003754.
DR KEGG; scac:106088805; -.
DR VEuPathDB; VectorBase:SCAU003754; -.
DR OrthoDB; 2875972at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProt.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 10.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45889:SF8; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 4.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07679; I-set; 3.
DR Pfam; PF13927; Ig_3; 2.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 9.
DR SMART; SM00408; IGc2; 8.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 9.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 9.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1120..1144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 101..198
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 203..305
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 315..404
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 409..504
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 512..601
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 606..700
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 707..798
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 803..891
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 897..996
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1001..1093
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 1087..1109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1161 AA; 127575 MW; 8121D43E6AAA647E CRC64;
METHDPEQMA LAVASNGMGA ADCAAPGNAC HHCHHRLYQE HCYQQQQCPV HERQEHQNYH
RRQHWQLRQA LHWIKNLQFV CHVISLLLVV NLPAFCHGQQ QKFRVTPHDL QVLEGAEAML
RCEVANLAGA VQWTKDGFAL GFSAVIPGFP RYSVLGDRKQ GAYNLRISNA STSDDAEYQC
QVGPARLNSA IRANAKLTVI SPPSSIEIKG YENNAKVEVR ENQDLSLKCV VSNAKPAAQI
VWYRGNVEYK PENRNDKVEE TTPKRFTTTS SLKLKPSADD DYTEYTCQAK HKALAPDMPM
RATVQLSVLY PPGPPYIEGY TQGETLRRGQ AVELVCRSRG GNPAAQLIWY KNGLQTKMAY
KTIGRMSENV YKFTAESSDN KARFRCEAIN VMSPAPLKAE VDLTVLFAPT HVSISGNNEA
RVGDVVPLTC TTAPSNPPAE IKWMVGGRQI RNATSRTMVS PEGGWITISN ITAVVEPNKR
SLVVICHGLN MQLTENVVST HTVNVLYPPS PPMISGYMEG QIIPAGSVQK LLCVSSGGNP
LATLTWYKND KRINSVIRTA DKSVSAEITI LANVTDNQAQ YRCEAANSAT EIPLFESTTL
SVHFAPETVK IRIEPEELKP GIEATIVCDS SSSNPPAKLS WWKDGISIQG INNTSKPGLW
GGTVSTLEFK VNITQEMNGV VYTCQSANEA LQRSVHEAVS LDVLYRPKFV PPPSSTAVGV
EGESLLVALQ ANANPMSITY TWTKDGQSLP SNGNGAEPRI FAEGSKLNFT KLYRNDAGVY
VCEARNSQGA ARINVTVVVE YGTTIKAVSE NVIVNPGEDA MLSCSVEGKP LTEDHVKWER
LGYDMTIKTS TTFANGTSYL HIKDAQREDV GNFRCIADNR VANPTSRDVL LIVKFAPEID
KSPTLMRAAS GTGERGRLPC RAQSSPRPQF IWRQEGKDLP VNRSYKYEVE EKKIDSLTYE
SILIIEKVAP ADYGAYECVA KNDLGQDIEP VRLDITSQPD TPLSLNILNV THDSVTVAWT
PGFDGGLKAS YRVRYREANR EQYKYIDGLP NSHKLTINGL RMNTLYLFSV MAYNDLGESK
YLPDLQKAHT KEAPPPSQPA SSLGGPPTTS ATPLGGTSGL LLLVGVASGI TIVALNILVI
GCCLHKRNQK RLKRGLYKCP G
//
