ID A0A1I8P2D8_STOCA Unreviewed; 695 AA.
AC A0A1I8P2D8;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 28-JUN-2023, entry version 35.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
GN Name=106087823 {ECO:0000313|EnsemblMetazoa:SCAU004224-PB};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU004224-PB, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU004224-PB}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU004224-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_013108452.1; XM_013252998.1.
DR RefSeq; XP_013108453.1; XM_013252999.1.
DR AlphaFoldDB; A0A1I8P2D8; -.
DR STRING; 35570.A0A1I8P2D8; -.
DR EnsemblMetazoa; SCAU004224-RA; SCAU004224-PA; SCAU004224.
DR EnsemblMetazoa; SCAU004224-RB; SCAU004224-PB; SCAU004224.
DR GeneID; 106087823; -.
DR KEGG; scac:106087823; -.
DR VEuPathDB; VectorBase:SCAU004224; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd20187; T-box_TBX1_10-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267:SF191; OPTOMOTOR-BLIND-RELATED-GENE-1, ISOFORM A; 1.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 177..362
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 79..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..435
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 562..582
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..419
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 695 AA; 76004 MW; 2AD7E58EC797416F CRC64;
MHQTVYMRPP PTSNIMGPTE CSSALMSSMP FMDNGSLTAN ITDYGCYTTT DHWSSPYMSA
LSPMKQIEAC IQTAGRDRGS YKPLESAESK MSDIETNSSC SGKDESVNTN AHFNDTNNNN
NNNNNNNNNN SNGNNNNKKS NKIKKDVTAT NGNATNGSSN KDEETLHPSL AQAVVVLETK
TLWDKFHEQG TEMIVTKSGR RMFPTFQVRI GGLDPQATYI MMMDFVPVDD KRYRYAFHNS
SWVVAGKADP ISPPRIHVHP DSPAPGANWM KQIISFDKLK LTNNQLDENG HIILNSMHRY
QPRFHIVYLP PKNASMDESE HSSHYRTFVF TETSFTAVTA YQNQRVTQLK IVSNPFAKGF
RDDGTSDAPP NSGMAMNQMS HESHARMKQH QQQHHQQQQQ QQQHHQQHQH HHSHQHAQHP
LKNGHKDATT ASATDIDGHN HSAMIVTSPS HHAMSNTPST PSTTGTSPDL ISYQTPNGHA
HNGLLNSNCI SPKTDHSHHS SSSPYGYSSQ NNANATAAAS SAAAVGNSGL ASSLSSSSTG
LMTSSPHAHH THLNLNLNSQ VISQSSPQQH HHHSHSAAAA TATSQVMSSA NLYSSLGQAY
AADNSNYGPI YHNPHYHGHS YGNPYEKIKV TGHMRQSHSH SHAHGIGNPN SSGVLGGNGV
SASANSYGMS SYQTFYGSAA HQMMRPGGYI DLVPR
//
