ID A0A1I8P2E5_STOCA Unreviewed; 1678 AA.
AC A0A1I8P2E5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Kinesin-like protein unc-104 {ECO:0000256|ARBA:ARBA00020751};
GN Name=106088678 {ECO:0000313|EnsemblMetazoa:SCAU004214-PN};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU004214-PN, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU004214-PN}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU004214-PN};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR RefSeq; XP_013109777.1; XM_013254323.1.
DR EnsemblMetazoa; SCAU004214-RN; SCAU004214-PN; SCAU004214.
DR VEuPathDB; VectorBase:SCAU004214; -.
DR OrthoDB; 126886at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd22705; FHA_KIF1; 1.
DR CDD; cd01365; KISc_KIF1A_KIF1B; 1.
DR CDD; cd01233; PH_KIFIA_KIFIB; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 6.10.250.2520; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR022164; Kinesin-like.
DR InterPro; IPR022140; Kinesin-like_KIF1-typ.
DR InterPro; IPR032405; Kinesin_assoc.
DR InterPro; IPR019821; Kinesin_motor_CS.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR049780; PH_KIFIA_KIFIB.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR47117:SF5; -; 1.
DR PANTHER; PTHR47117; STAR-RELATED LIPID TRANSFER PROTEIN 9; 1.
DR Pfam; PF12473; DUF3694; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF12423; KIF1B; 1.
DR Pfam; PF00225; Kinesin; 1.
DR Pfam; PF16183; Kinesin_assoc; 1.
DR Pfam; PF00169; PH; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00129; KISc; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS00411; KINESIN_MOTOR_1; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00283};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00283}.
FT DOMAIN 3..352
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT DOMAIN 1545..1643
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 404..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1467..1489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 360..387
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 640..689
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 98..105
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1678 AA; 189444 MW; 5C0F3167F4A0D888 CRC64;
MSSVKVAVRV RPFNSREIGR ESKCIIEMFD NTTTAITNPK VPPNSSESVK RFNFDYSYWS
HDPKDPCFST QSMVYKDIGE EMLQHSFDGY NVCIFAYGQT GAGKSYTMMG KQEEHQEGII
PMICKDLFRR IASTESADLK YSVEVSYMEI YCERVRDLLN PKNKGNLRVR EHPLLGPYVE
DLSKLAVTSY QDIHDLIDEG NKARTVAATN MNETSSRSHA VFTIFFTQQR HDTMTDLITE
KVSKISLVDL AGSERADSTG AKGTRLKEGA NINKSLTTLG KVISALAEIA SKNKKSKKAD
FIPYRDSVLT WLLRENLGGN SKTAMIAAIS PADINYDETL STLRYADRAK AIVCKAVVNE
DANAKLIREL KEEIQKLRDL LKAEGIEVQE GPDGKVVCEK RDTNKDEIKG GGGTGGGGTI
KSPINNRNRN GSTTEMAVDQ LQASEKLIAE LNETWEEKLK RTEEIRLQRE AVFAEMGVAV
KEDGITVGVF SPKKTPHLVN LNEDPNLSEC LLYYIKDGIT RLGTHEANVP QDIQLSGSHI
LKEHCTFENR NNQVTLIPHK DALVYLNGRQ LMEPEVLRTG SRVILGKNHV FRFTNPDQAR
EIREKIAENT ENENEKCDTQ EVDWNFAQCE LLEKQGIDLK AEMKKRLDVL EEQYKREKLQ
ADQEFEEQRK SYEARIDALQ KQVEEQSMTM SMYSSYTPED LQDEEVYSNP AYESCWSARE
AGLAAWAFRK WRYHQFTSLR DDLWGNAIFL KEANAISVEL KKKVQFQFTL LTDTLYSPLP
PELASSASPL QVEDEFGTPP VSKTLVAVEV TDTKNGATHY WSLEKLRQRL ELMREMYHNE
AELSPSSPDY NVESLTGGDP FYDRFPWFRM VGRSFVYLSN LLYPVPLVHK VAIVNERGDV
RGYLRIAVQP VLDEESLDFN NGVKQSARLI FNEDDAKPRY RALNEKDDVQ RYIENGSGLD
SKLEELGDVD SGRGIDSNSA SECQEAQDEP GEHLQIGKEF TFRVTVLQAT GIGAEYADIF
CQFNFLHRHE EAFSTEPVKN SAGDRLGFYH VQNITVPVTK SFIEYLKTQP IMFKVFGHYQ
THPLHKDAKQ EFVSRPPPRR MLPPSIPISQ PVRSPKFGPL PCPPSSTVLA KHDVLVWFEI
CELAPNGEYV PAVVEHSDDL PCRGLFLLHQ GIQRRIRITI VHEPTAEVKW KDIRELVVGR
IRNTPESSDD DEDSCVLSLG LFPGEVIEVP GDDRSFFRFE AAWDSSLHNS ALLNRVSQGG
ETVYITLSAY LELENCARPA IITKDLSMII YGRDARTGPR SLKHLFSGQY RNPEANRLSG
VYELSLRRAS DAGSPGVQRR QRRVLDTSST YVRGEENLHG WRPRGDSLIF DHQWELEKLT
RLEEVGRVRH LLLLRERLGM DTNPNPTTKT EKDVCNLAAK AATSPVHMVI PPSPQTPVKD
SQQIVPEREY NEREIELMNK CLKLVQGRSS KSENNDNQTQ SDVSPSDEGC ADMTVSCISS
SSIELCSPDR SDAPNGWEAP APATQPALPL RLYVPELEEI RVSPVVARKG LLNVLEHGGS
GWKKRWVIVR RPYVFIYKSE KDPVERAILN LGTAQVECSE DQAAMVKIPN TFSVVTKHRG
YLLQTLGDKE VHDWLYAINP LLAGQIRSRL ARRTQETASQ TASQIQATIA TNTGSNNK
//
