ID   A0A1I8P3T6_STOCA        Unreviewed;       837 AA.
AC   A0A1I8P3T6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Pickpocket protein 19-like {ECO:0008006|Google:ProtNLM};
GN   Name=106080564 {ECO:0000313|EnsemblMetazoa:SCAU004576-PA};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU004576-PA, ECO:0000313|Proteomes:UP000095300};
RN   [1] {ECO:0000313|EnsemblMetazoa:SCAU004576-PA}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU004576-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   RefSeq; XP_013097436.1; XM_013241982.1.
DR   AlphaFoldDB; A0A1I8P3T6; -.
DR   STRING; 35570.A0A1I8P3T6; -.
DR   EnsemblMetazoa; SCAU004576-RA; SCAU004576-PA; SCAU004576.
DR   KEGG; scac:106080564; -.
DR   VEuPathDB; VectorBase:SCAU004576; -.
DR   OrthoDB; 3683954at2759; -.
DR   Proteomes; UP000095300; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 2.
DR   Gene3D; 1.10.287.770; YojJ-like; 2.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF301; AMILORIDE-SENSITIVE NA+ CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 3.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        375..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        786..815
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   837 AA;  96674 MW;  0FAB87F6B444D681 CRC64;
     MYTMLTQRHR DQVLITLVDT SREPIYTTSF PAVAVCPLNH VNWIRYTLAE EKFLPRNPSM
     ETKRIFAELL AALEIPYSVY NIILYDLLLF VAFRCEEIFD WCIYDDTEYD CCKIFVQERT
     ERGICLVFNS MVSTESKMKQ LSDNYYPWRA RTGGEGSGLS FKLRYNKDYV RPGSKLPFSF
     SILIKEADEW SYSPFNILKP NSRNTIMVTP IFTETSANTR HIDPQKRRCM FSDETSLIYD
     RIEGLPFNRL NCLVQCEQKF VMKYCNCTLS MFFPGMPQYR NKECRVSDLK CIYEHKDIFN
     YLKGPLQDEY INDTRRGMVC DCVHNCVSLL FLVSINSQPL QSPNTTDPEI DVDIYFAKNT
     MTKYAARLQY TYMDLAANFG GVLGLCLGAS ALSLLRFGSQ PSAMSKQKII LQSLLKFCDS
     GFHGANHAID SKNRLVLRVF WLLIVFGALV GCIFMYWKLT GRHQEKILVT VVESSQKPIH
     NIAFPAVAVC PFNHINWMRH KSAEEKFLPQ NSTEETIKIF HDLLVAMERL TFTTLNDIEL
     LLRNPNIPKS IQNIVLYDLA LFMAFRCNEI FVWCIYDETH LDCCKVFITE RTERGICLVF
     NSLISDESKI KQLSDNYYPW RARTGGEGSG LSFKLRYNKA FVRPGSTLPF SFSILIKEAD
     EWSYSPFNIL KPNSRNTIMV TPIFTETSAN TRHIDPQKRR YIFNYIKGPL QDEFINDTSR
     GMVCNCVHNC VSLIFLLSIN SQHLQSANNT VPEIDLDVHF VKNTMTKYAS RLQYTNMDLA
     ANFGGILGLC LGASVLSVAE VVYAAIRTLF ALLIFKWNKR RRQRRVHKVK IYINNAP
//