ID A0A1I8P7U9_STOCA Unreviewed; 120 AA.
AC A0A1I8P7U9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Insulin-like domain-containing protein {ECO:0000259|SMART:SM00078};
GN Name=106094793 {ECO:0000313|EnsemblMetazoa:SCAU005637-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU005637-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU005637-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU005637-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBUNIT: Heterodimer of a B chain and an A chain linked by two
CC disulfide bonds. {ECO:0000256|ARBA:ARBA00011207}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613,
CC ECO:0000256|RuleBase:RU000406}.
CC -!- SIMILARITY: Belongs to the insulin family.
CC {ECO:0000256|ARBA:ARBA00009034, ECO:0000256|RuleBase:RU000406}.
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DR RefSeq; XP_013117485.1; XM_013262031.1.
DR AlphaFoldDB; A0A1I8P7U9; -.
DR STRING; 35570.A0A1I8P7U9; -.
DR EnsemblMetazoa; SCAU005637-RA; SCAU005637-PA; SCAU005637.
DR GeneID; 106094793; -.
DR KEGG; scac:106094793; -.
DR VEuPathDB; VectorBase:SCAU005637; -.
DR OrthoDB; 3028803at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR CDD; cd04366; IlGF_insulin_bombyxin_like; 1.
DR Gene3D; 1.10.100.10; Insulin-like; 1.
DR InterPro; IPR016179; Insulin-like.
DR InterPro; IPR036438; Insulin-like_sf.
DR InterPro; IPR040228; Insulin-relat-peptide_inver.
DR InterPro; IPR022353; Insulin_CS.
DR InterPro; IPR022352; Insulin_family.
DR PANTHER; PTHR13647:SF4; INSULIN-LIKE PEPTIDE 1-RELATED; 1.
DR PANTHER; PTHR13647; INSULIN-LIKE PEPTIDE 2-RELATED; 1.
DR Pfam; PF00049; Insulin; 1.
DR PRINTS; PR00276; INSULINFAMLY.
DR SMART; SM00078; IlGF; 1.
DR SUPFAM; SSF56994; Insulin-like; 1.
DR PROSITE; PS00262; INSULIN; 1.
PE 3: Inferred from homology;
KW Cleavage on pair of basic residues {ECO:0000256|ARBA:ARBA00022685};
KW Secreted {ECO:0000256|RuleBase:RU000406};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..120
FT /note="Insulin-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009326183"
FT DOMAIN 19..119
FT /note="Insulin-like"
FT /evidence="ECO:0000259|SMART:SM00078"
SQ SEQUENCE 120 AA; 13623 MW; 533CCE6538ED5CA9 CRC64;
MKILSVLLLF AALYEINGSR FCGPTLTQVL EMVCYNGYNP MIMSKKSSNK PVHHDMDIPD
KFNEIDDVSG LKPDSLLNDL LYGNHVNRLA KTRRHRHLGG VYDECCRKDC TLDELAGYCL
//
