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Database: UniProt
Entry: A0A1I8P9D4_STOCA
LinkDB: A0A1I8P9D4_STOCA
Original site: A0A1I8P9D4_STOCA 
ID   A0A1I8P9D4_STOCA        Unreviewed;      5107 AA.
AC   A0A1I8P9D4;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:SCAU006019-PG};
GN   Name=106095874 {ECO:0000313|VectorBase:SCAU006019-PG};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PG};
RN   [1] {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PG}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000095300,
RC   ECO:0000313|VectorBase:SCAU006019-PG};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:SCAU006019-PG}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:SCAU006019-PG};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   RefSeq; XP_013118753.1; XM_013263299.1.
DR   GeneID; 106095874; -.
DR   VectorBase; SCAU006019-RG; SCAU006019-PG; SCAU006019.
DR   Proteomes; UP000095300; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095300};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095300};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4438   4458       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4633   4651       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4713   4735       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4902   4924       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4978   5001       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       94    148       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      155    200       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      210    264       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      270    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      336    394       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      577    803       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1032   1217       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1447   1667       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      460    480       {ECO:0000256|SAM:Coils}.
FT   COILED     3783   3803       {ECO:0000256|SAM:Coils}.
FT   COILED     4570   4590       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5107 AA;  579071 MW;  D5A469E9D307314B CRC64;
     MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI ADKNVPPDLS
     QCVFVIEQAL SVRALQELVT AAGSETGKGT GSGHRTLLYG NAILLRHNNS DMYLACLSTS
     SSNDKLSFDV GLQEHSQGEA CWWTVHPASK QRSEGEKVRV GDDLILVSVA TERYLHTTKE
     NEQSIVNASF HVTHWSVQPY GTGISRMKYV GYVFGGDVLR FFHGGDECLT IPSTWGREAG
     QNIVVYEGGS VMSQARSLWR LELARTKWTG GFINWFHPMR IRHITTGRYL GVNENNELIL
     VRKDEASIAT TTFCLRQEKD DEKKVLEDKD LEVIGSPIIK YGDTTVIVQH CETCLWLSYK
     SYETKKKGVG KVEEKQAILH EEGKMDDCLD FSRSQEEESK TARVIRKCSS LFTQFINALE
     TLQSNRRHSV FFQKVNLNEM VMCLEDLINY FSQPPDDMEH EEKQNRFRAL RNRQDLFQEE
     GVLNLILEAI DKINIITSQG FLASFLAGDE TGQSWDLIST YLYQLLAAII QGNHTNCAQF
     ANSNRLNWLF SRLGSQASSE GSGMLDVLHC VLIDSPEALN MMRDEHIKVI ISLLEKHGRD
     PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTQ LVDHVASIRP NIFVGRVANS
     AMYQKWYFEV TMDHIEQTTH MMPHLRIGWA NTSGYVPYPG GGKKWGGNGV GDDLYSFGFD
     GAYLWTGGRK TLVTDMIPEQ PYIRKGDVIG VTIDLSVPII TFTFNGLKVK GCFRDFNLDG
     MFFPVMSCSS KLSCRFLFGG DHGRMKFAPP HGFSPLVQCL MPHQILSLDP CFYFGNLNKN
     VLAGPWMIED DTAFVPNPVD TSGVSLPSSV DQIKEKLAEN IHEMWALNKI EAGWSWGEHR
     DDYQRIHPCL TQFEKLPPAE KRYDNQLAVQ TLKTIIALGY YITMDKPPAR IRPIRLPNEI
     FMQANGYKPA PLDLSAATLT PKLEELVDQL AENTHNLWAR ERIQQGWTYG LNEDSENLRS
     PHLVPYSKVD EAIKKANRDT ASETVRTLLV YGYVLDPPTG EGNEALLAEA LRLKFAAFRT
     YRVERNYAVT SGKWYFEFEV LTAGPMRVGW ARADCNPGAM LGSDDTSWAF DGHNVTKVHA
     GSVEHFGVRY EAGDVIGCFI DVKEQTISFS LNGELLMDAL GGETTFAEVT AEGVGFVPAC
     TLGVGQKARL IYGQDVDSLK FFTTCGLQEG YEPFCVNMRR PVTHWYTKDQ PIFENTEEMP
     DCRIDVTRIP GGADTPPHLK ISHNTFETME KANWEFLRLS LPVTCMDEFI SEVEKARRWE
     EIKIRQYRLM REAQEMAQHQ PSAHMDHMLK SGFSMNDIKG LNRNYEDTAE ADENMARSPV
     RPARRASITR NITFESDLGM PEELQRSTSA LDMNGMEDGM VDDKKKRGRS PFKFFSKKSR
     DQSKDKTPGR APEVSPERRT GVQGRTMMGG QLAAKPPSLR LNNTEMPQTP TQGPKALSGG
     NLGQPTVESS GNEMFDAECL KLINEYFYGV RIFPGQDPTH VYVGWVTTQY HLHSKEFNKD
     KVRRASVIIE DDYEMPIQHI NRQSCYVVRA DELFNEVTQD ASGKGASQGM FVGCFVDTAT
     GIISFTCEGK QTSHRWQMEP NTKLFPAIFV EATSKEILQI ELGRTATTLP LSAAVLPTSD
     KHINPQSPPR LKVQCLRPHQ WARVPNTALQ VHALKLSDLR GWSMLCEDPV SMLALHIPEE
     DRCIDILELI EMDKLLSFHA HSLTLYAALC YQSNYRAAHA LCQHVDQKQL LYAIRSEYMS
     GPLRQGFYDL LIALHLESHA TTMEVCKMEY IIPLGPELKF LYDDEEMRHS LRSLVTESVR
     PQMRMTEITE PIPDIDHLYS PKFPLEVVRE FVMEALKEAV EINQVHNRDP IGWTNENLFL
     PLVKLTDRLL LVGVMTDDDV QKLLVMIDPE TWDPTFEKDG KDEHRKGLLT MKMAEGAKLQ
     MCYLLHHLYD IQLRHRVESI IAFSHDFVGD LQSDQLRRYI EIKQSDLPSA VAAKKTKEFR
     CPPREQMNQI LCFKNLEPDD HENCTCGLEL RGSLYDFHDS LMKKVSLNAL QEPDESESTT
     IEEIKTGPIT KIYNFINTVK ELEEGPKEVE EPEKKTPEEV FRKVLIKTIV SWAEESQIET
     PKLVREMFSL LVRQYDTVGE LVRALEKTYV INNRARDDVA EMWVGLSQIR ALLPVQMSQE
     EEELMRKRLW KLVNNATFFQ HPDLIRILRI HENVMAVMMN TLGRRAQAQS DAPAQQEGGE
     GAPPKEKDTS HEMVVACCRF LCYFCRTGRQ NQKAMFDHFD FLLDNANILL ARPSLRGSTP
     LDVAYSSLME NTELALALRE HYLEKIAVYL SRCGLQSNSE LVEKGYPDLG WDPVEGERYL
     DFLRYCVWVN GESVEENANL VIRLLIRRPE CLGPALRGEG EGLFRAIVEA NRMSERITDR
     CKMQDEAEGT IAGLNFTHPL PESDDDEDYI DTGAAILNFY CTLVDLLGRC APDASVIEQG
     KNESLRARAI LRSLVPLEDL QGVLSLKFTL TQTAPGEEKP KSDMPSGLLP NNKQSIVLFL
     ERVYGIETQE LFYRLLEDAF LPDLRTATIL DKSDGSESDM ALSMNRYIGN SILPLLIKHS
     KFYNEAENYA SLLDATLHTV YRLSKNRMLT KGQREAVSDF LVALTSQMQP AMLLKLLRKL
     TVDVSKLSEY TTVALRLLTL HFDRCAKYYG SSQGQGSYGA SSDEEKRLTM LLFSNIFDSL
     SNMDYDPELF GKALPCLIAI GCALPPDYSL SKNLDEDYYG RQSGAPDQPQ YDPNPIETST
     VVLTHDYNSL VEKFSEHYHD AWASRRLESG WTYGEVRSDT DRKHPRLKPC NMLSDYERER
     YRDPVRECLK ALLALGWTIE HSEIEVAQNN RGSTRRQSKP QINDFQNEGS PFNYNPHPVD
     MTNLTLSREM QNMAERLAEN SHDIWAKKKK EELGSCGGVI HPQLVPYDLL TDKEKRKDRE
     RSQEFLKYMQ YQGYKLHKPS KGGALEGEGG ATQTAAELRF SYSLLEKLIQ YLDRASINMK
     LLKPSTTFSR RTSFKTASRD IKFFSKVVLP LMEKYFSTHR NYFIAVATAT NNVGAASLKE
     KEMVAAIFCK LASLLRNRLT AFGPDVRITV RCLQVLVKGI DARTLVKNCP EFIRTSMLTF
     FNQTADDLGN TILNLQDGKY SHLRGTHLKT STSLGYINQV VMPVLTAMFD HLAACDYGSD
     LLLDEIQVAS YKILAALYHL GTDGTLTQDR KYLKTEIERH RPALGSCLGA FSSCFPVAFF
     EPHLNKHNQF SLLNRIADHS LEAQDIMVKM ESCMPNLETI LGEVDQFVES DKTYSDAPHV
     IDVILPLLCS YLPFWWSQGP DNVSPTSGNH VTMVTADHMN SLLRNVLNMI KKNIGNDNAP
     WMTRIAAYTQ QIIINTSEEL LKDPFLPLAE RVKKRTENMF HKEESMRGFI KSATDDTSQV
     ETQLQEDWQL LVRDIYSFYP LLIKYVDLQR NHWLKDNIPE AEELYNHVAE IFNIWSKSQY
     FLKEEQNFIS ANEIDNMALI MPTATRRSAI SEGAPVTGGK VKKKKKNRDK KRDKDKEIQA
     SLMVACLKRL LPVGLNLFAG REQELVQHCK DRYLKKMAEY EVIEFARNQL TLPDKLDPSD
     EMSWQHYLYS KLGKKEEPTE EQNALEKAAN QNDKGRDKTQ ETVDRIVAMA KVLFGLHMID
     HPQQQSKNVY RSVVSIQRKR AVIACFRQTS LHSLPRHRAC NIFARTYHEQ WLQEENVGQE
     VMIEDLTQTF EDFEKSKKEE DETEAKPDPL TQLVTTFCRG AMTERSGALQ EDLLYMSYAQ
     IAAKSCGEEE EEGGDEEGGE EEGEGTSIHE QEMEKQKLLF HQARLSNRGV AEMVLLHISA
     SKGIPSEMVM TTLNLGISIL RGGNIDIQMG MLNHLKEKKD VGFFTSIAGL MNSCSVLDLD
     AFERNTKAEG LGVGSEGAAG EKNMHDAEFT CALFRFIQLT CEGHNLDWQN YLRTQAGNTT
     TVNVVICTVD YLLRLQESIM DFYWHYSSKE IIDPAGKANF FKAIGVASQV FNTLTEVIQG
     PCTLNQQALA HSRLWDAVGG FLFLFSHMQE KLSKHSSQVD LLKELLNLQK DMITMMLSML
     EGNVVNGTIG KQMVDTLVES ASNVELILKY FDMFLKLKDL IESPSFMEID IKNEGWVTPK
     DFRDKMEQSK NYTPEEIDFL LACCERNHEG KIDYVAFVDR FHEPSTEIGF NLAVLLTNLS
     EHMPNEPRLA RFLETAGSVL NYFEPFLGRI EILGSSKRIE RVYFEIKDSN IEQWEKPQIK
     ESKRAFFYSI VTEGGDKEKL EAFVNFCEDA IFEMTHASGL MATDDGGSNV KRDTSYSSYM
     SEEEEERAAR DPIRRTITAV KDGLKFGVHM FSPANIKHQI GVMQTKTVPE LIIGFFKAIF
     YMFYYTGYAH FAVLRYIFGI LMNLMRGPAP EEVEEPPQEE ETFGRALPPL PIEEPPSTVQ
     AFGLDINKEE NGQYKVTVHE SSGGSPTSSM EETGESSPED GATTAEAGAE GEPHHQEPVS
     IVDLLGGEAA KKAAQERQEA QKAQEAAMAS IEAEAKKSSS TTQETPAVNQ IDFSQYTHRA
     VSFLARNFYN LKYVALVLAF SINFMLLFYK VTSFANDEES SGDDVLILGS GSGGGMAGSG
     MGSGDGSGDG GDEEDELPEM VHVDEDFFYM EHVIRMAALL HSLVSLAMLI AYYHLKVPLA
     IFKREKEIAR RLEFDGLFIA EQPEDDDFKS HWDKLVISAK SFPVNYWDKF VKKKVRQKYS
     ETYDFDSISN LLGMEKSAFM AQESEEGGFV KYITNIDWRY QVWKAGVTFT DNAFLYSLWY
     FSFSVMGNFN NFFFAAHLLD VAVGFKTLRT ILQSVTHNGK QLVLTVMLLT IIVYIYTVIA
     FNFFRKFYIQ EEDDEVDKKC HDMLTCFVFH LYKGVRAGGG IGDEIGDPVG DEYEVYRIIF
     DITFFFFVIV ILLAIIQGLI IDAFGELRDQ LESVKENMES NCFICGMGKD FFDIVPHGFD
     THVQKEHNLA NYMFFLMHLI NKPDTEYTGQ ETYVWNMYQQ RSWDFFPVGD CFRKQYEDEL
     SGGGGGG
//
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