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Database: UniProt
Entry: A0A1I8P9E0_STOCA
LinkDB: A0A1I8P9E0_STOCA
Original site: A0A1I8P9E0_STOCA 
ID   A0A1I8P9E0_STOCA        Unreviewed;      5109 AA.
AC   A0A1I8P9E0;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:SCAU006019-PK};
GN   Name=106095874 {ECO:0000313|VectorBase:SCAU006019-PK};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PK};
RN   [1] {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PK}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000095300,
RC   ECO:0000313|VectorBase:SCAU006019-PK};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:SCAU006019-PK}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:SCAU006019-PK};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   RefSeq; XP_013118751.1; XM_013263297.1.
DR   GeneID; 106095874; -.
DR   VectorBase; SCAU006019-RK; SCAU006019-PK; SCAU006019.
DR   Proteomes; UP000095300; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095300};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095300};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4440   4460       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4635   4653       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4715   4737       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4904   4926       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4980   5003       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       94    148       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      155    200       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      210    264       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      270    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      336    394       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      577    803       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1032   1217       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1447   1667       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      460    480       {ECO:0000256|SAM:Coils}.
FT   COILED     3778   3798       {ECO:0000256|SAM:Coils}.
FT   COILED     4572   4592       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5109 AA;  579135 MW;  E0019AEC585B1CCE CRC64;
     MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI ADKNVPPDLS
     QCVFVIEQAL SVRALQELVT AAGSETGKGT GSGHRTLLYG NAILLRHNNS DMYLACLSTS
     SSNDKLSFDV GLQEHSQGEA CWWTVHPASK QRSEGEKVRV GDDLILVSVA TERYLHTTKE
     NEQSIVNASF HVTHWSVQPY GTGISRMKYV GYVFGGDVLR FFHGGDECLT IPSTWGREAG
     QNIVVYEGGS VMSQARSLWR LELARTKWTG GFINWFHPMR IRHITTGRYL GVNENNELIL
     VRKDEASIAT TTFCLRQEKD DEKKVLEDKD LEVIGSPIIK YGDTTVIVQH CETCLWLSYK
     SYETKKKGVG KVEEKQAILH EEGKMDDCLD FSRSQEEESK TARVIRKCSS LFTQFINALE
     TLQSNRRHSV FFQKVNLNEM VMCLEDLINY FSQPPDDMEH EEKQNRFRAL RNRQDLFQEE
     GVLNLILEAI DKINIITSQG FLASFLAGDE TGQSWDLIST YLYQLLAAII QGNHTNCAQF
     ANSNRLNWLF SRLGSQASSE GSGMLDVLHC VLIDSPEALN MMRDEHIKVI ISLLEKHGRD
     PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTQ LVDHVASIRP NIFVGRVANS
     AMYQKWYFEV TMDHIEQTTH MMPHLRIGWA NTSGYVPYPG GGKKWGGNGV GDDLYSFGFD
     GAYLWTGGRK TLVTDMIPEQ PYIRKGDVIG VTIDLSVPII TFTFNGLKVK GCFRDFNLDG
     MFFPVMSCSS KLSCRFLFGG DHGRMKFAPP HGFSPLVQCL MPHQILSLDP CFYFGNLNKN
     VLAGPWMIED DTAFVPNPVD TSGVSLPSSV DQIKEKLAEN IHEMWALNKI EAGWSWGEHR
     DDYQRIHPCL TQFEKLPPAE KRYDNQLAVQ TLKTIIALGY YITMDKPPAR IRPIRLPNEI
     FMQANGYKPA PLDLSAATLT PKLEELVDQL AENTHNLWAR ERIQQGWTYG LNEDSENLRS
     PHLVPYSKVD EAIKKANRDT ASETVRTLLV YGYVLDPPTG EGNEALLAEA LRLKFAAFRT
     YRVERNYAVT SGKWYFEFEV LTAGPMRVGW ARADCNPGAM LGSDDTSWAF DGHNVTKVHA
     GSVEHFGVRY EAGDVIGCFI DVKEQTISFS LNGELLMDAL GGETTFAEVT AEGVGFVPAC
     TLGVGQKARL IYGQDVDSLK FFTTCGLQEG YEPFCVNMRR PVTHWYTKDQ PIFENTEEMP
     DCRIDVTRIP GGADTPPHLK ISHNTFETME KANWEFLRLS LPVTCMDEFI SEVEKARRWE
     EIKIRQYRLM REAQEMAQHQ PSAHMDHMLK SGFSMNDIKG LNRNYEDTAE ADENMARSPV
     RPARRASITR NITFESDLGM PEELQRSTSA LDMNGMEDGM VDDKKKRGRS PFKFFSKKSR
     DQSKDKTPGR APEVSPERRT GVQGRTMMGG QLAAKPPSLR LNNTEMPQTP TQGPKALSGG
     NLGQPTVESS GNEMFDAECL KLINEYFYGV RIFPGQDPTH VYVGWVTTQY HLHSKEFNKD
     KVRRASVIIE DDYEMPIQHI NRQSCYVVRA DELFNEVTQD ASGKGASQGM FVGCFVDTAT
     GIISFTCEGK QTSHRWQMEP NTKLFPAIFV EATSKEILQI ELGRTATTLP LSAAVLPTSD
     KHINPQSPPR LKVQCLRPHQ WARVPNTALQ VHALKLSDLR GWSMLCEDPV SMLALHIPEE
     DRCIDILELI EMDKLLSFHA HSLTLYAALC YQSNYRAAHA LCQHVDQKQL LYAIRSEYMS
     GPLRQGFYDL LIALHLESHA TTMEVCKMEY IIPLGPELKF LYDDEEMRHS LRSLVTESVR
     PQMRMTEITE PIPDIDHLYS PKFPLEVVRE FVMEALKEAV EINQVHNRDP IGWTNENLFL
     PLVKLTDRLL LVGVMTDDDV QKLLVMIDPE TWDPTFEKDG KDEHRKGLLT MKMAEGAKLQ
     MCYLLHHLYD IQLRHRVESI IAFSHDFVGD LQSDQLRRYI EIKQSDLPSA VAAKKTKEFR
     CPPREQMNQI LCFKNLEPDD HENCTCGLEL RGSLYDFHDS LMKKVSLNAL QEPDESESTT
     IEEIKTGPIT KIYNFINTVK ELEEGPKEVE EPEKKTPEEV FRKVLIKTIV SWAEESQIET
     PKLVREMFSL LVRQYDTVGE LVRALEKTYV INNRARDDVA EMWVGLSQIR ALLPVQMSQE
     EEELMRKRLW KLVNNATFFQ HPDLIRILRI HENVMAVMMN TLGRRAQAQS DAPAQQEGGE
     GAPPKEKDTS HEMVVACCRF LCYFCRTGRQ NQKAMFDHFD FLLDNANILL ARPSLRGSTP
     LDVAYSSLME NTELALALRE HYLEKIAVYL SRCGLQSNSE LVEKGYPDLG WDPVEGERYL
     DFLRYCVWVN GESVEENANL VIRLLIRRPE CLGPALRGEG EGLFRAIVEA NRMSERITDR
     CKMQDEAEGT IAGLNFTHPL PESDDDEDYI DTGAAILNFY CTLVDLLGRC APDASVIEQG
     KNESLRARAI LRSLVPLEDL QGVLSLKFTL TQTAPGEEKP KSDMPSGLLP NNKQSIVLFL
     ERVYGIETQE LFYRLLEDAF LPDLRTATIL DKSDGSESDM ALSMNRYIGN SILPLLIKHS
     KFYNEAENYA SLLDATLHTV YRLSKNRMLT KGQREAVSDF LVALTSQMQP AMLLKLLRKL
     TVDVSKLSEY TTVALRLLTL HFDRCAKYYG SSQGQGSYGA SSDEEKRLTM LLFSNIFDSL
     SNMDYDPELF GKALPCLIAI GCALPPDYSL SKNLDEDYYG RQSGAPDQPQ YDPNPIETST
     VVLTHDYNSL VEKFSEHYHD AWASRRLESG WTYGEVRSDT DRKHPRLKPC NMLSDYERER
     YRDPVRECLK ALLALGWTIE HSEIEVAQNN RGSTRRQSKP QINEGSPFNY NPHPVDMTNL
     TLSREMQNMA ERLAENSHDI WAKKKKEELG SCGGVIHPQL VPYDLLTDKE KRKDRERSQE
     FLKYMQYQGY KLHKPSKGGA LEGEGGATQT AAELRFSYSL LEKLIQYLDR ASINMKLLKP
     STTFSRRTSF KTASRDIKFF SKVVLPLMEK YFSTHRNYFI AVATATNNVG AASLKEKEMV
     AAIFCKLASL LRNRLTAFGP DVRITVRCLQ VLVKGIDART LVKNCPEFIR TSMLTFFNQT
     ADDLGNTILN LQDGKYSHLR GTHLKTSTSL GYINQVVMPV LTAMFDHLAA CDYGSDLLLD
     EIQVASYKIL AALYHLGTDG TLTQDRKYLK TEIERHRPAL GSCLGAFSSC FPVAFFEPHL
     NKHNQFSLLN RIADHSLEAQ DIMVKMESCM PNLETILGEV DQFVESDKTY SDAPHVIDVI
     LPLLCSYLPF WWSQGPDNVS PTSGNHVTMV TADHMNSLLR NVLNMIKKNI GNDNAPWMTR
     IAAYTQQIII NTSEELLKDP FLPLAERVKK RTENMFHKEE SMRGFIKSAT DDTSQVETQL
     QEDWQLLVRD IYSFYPLLIK YVDLQRNHWL KDNIPEAEEL YNHVAEIFNI WSKSQYFLKE
     EQNFISANEI DNMALIMPTA TRRSAISEGA PVTGGKVKKK KKNRDKKRDK DKEIQASLMV
     ACLKRLLPVG LNLFAGREQE LVQHCKDRYL KKMAEYEVIE FARNQLTLPD KLDPSDEMSW
     QHYLYSKLGK KEEPTEEQNA LEKAANQNDK GRDKTQETVD RIVAMAKVLF GLHMASRSKK
     KSKSRSSKIT LARRQAVISS LRAIHLYRIS RHRACNIFAR TYHEQWLQEE NVGQEVMIED
     LTQTFEDFEK SKKEEDETEA KPDPLTQLVT TFCRGAMTER SGALQEDLLY MSYAQIAAKS
     CGEEEEEGGD EEGGEEEGEG TSIHNSMAKL MEQEMEKQKL LFHQARLSNR GVAEMVLLHI
     SASKGIPSEM VMTTLNLGIS ILRGGNIDIQ MGMLNHLKEK KDVGFFTSIA GLMNSCSVLD
     LDAFERNTKA EGLGVGSEGA AGEKNMHDAE FTCALFRFIQ LTCEGHNLDW QNYLRTQAGN
     TTTVNVVICT VDYLLRLQES IMDFYWHYSS KEIIDPAGKA NFFKAIGVAS QVFNTLTEVI
     QGPCTLNQQA LAHSRLWDAV GGFLFLFSHM QEKLSKHSSQ VDLLKELLNL QKDMITMMLS
     MLEGNVVNGT IGKQMVDTLV ESASNVELIL KYFDMFLKLK DLIESPSFME IDIKNEGWVT
     PKDFRDKMEQ SKNYTPEEID FLLACCERNH EGKIDYVAFV DRFHEPSTEI GFNLAVLLTN
     LSEHMPNEPR LARFLETAGS VLNYFEPFLG RIEILGSSKR IERVYFEIKD SNIEQWEKPQ
     IKESKRAFFY SIVTEGGDKE KLEAFVNFCE DAIFEMTHAS GLMATDDGGS NVKRDTSYSS
     YMSEEEEERA ARDPIRRTIT AVKDGLKFGV HMFSPANIKH QIGVMQTKTV PELIIGFFKA
     IFYMFYYTGY AHFAVLRYIF GILMNLMRGP APEEVEEPPQ EEETFGRALP PLPIEEPPST
     VQAFGLDINK EENGQYKVTV HESSGGSPTS SMEETGESSP EDGATTAEAG AEGEPHHQEP
     VSIVDLLGGE AAKKAAQERQ EAQKAQEAAM ASIEAEAKKS SSTTQETPAV NQIDFSQYTH
     RAVSFLARNF YNLKYVALVL AFSINFMLLF YKVTSFANDE ESSGDDVLIL GSGSGGGMAG
     SGMGSGDGSG DGGDEEDELP EMVHVDEDFF YMEHVIRMAA LLHSLVSLAM LIAYYHLKVP
     LAIFKREKEI ARRLEFDGLF IAEQPEDDDF KSHWDKLVIS AKSFPVNYWD KFVKKKVRQK
     YSETYDFDSI SNLLGMEKSA FMAQESEEGG FVKYITNIDW RYQVWKAGVT FTDNAFLYSL
     WYFSFSVMGN FNNFFFAAHL LDVAVGFKTL RTILQSVTHN GKQLVLTVML LTIIVYIYTV
     IAFNFFRKFY IQEEDDEVDK KCHDMLTCFV FHLYKGVRAG GGIGDEIGDP VGDEYEVYRI
     IFDITFFFFV IVILLAIIQG LIIDAFGELR DQLESVKENM ESNCFICGMG KDFFDIVPHG
     FDTHVQKEHN LANYMFFLMH LINKPDTEYT GQETYVWNMY QQRSWDFFPV GDCFRKQYED
     ELSGGGGGG
//
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