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Database: UniProt
Entry: A0A1I8P9E1_STOCA
LinkDB: A0A1I8P9E1_STOCA
Original site: A0A1I8P9E1_STOCA 
ID   A0A1I8P9E1_STOCA        Unreviewed;      5125 AA.
AC   A0A1I8P9E1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:SCAU006019-PL};
GN   Name=106095874 {ECO:0000313|VectorBase:SCAU006019-PL};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PL};
RN   [1] {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PL}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000095300,
RC   ECO:0000313|VectorBase:SCAU006019-PL};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:SCAU006019-PL}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:SCAU006019-PL};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   RefSeq; XP_013118742.1; XM_013263288.1.
DR   GeneID; 106095874; -.
DR   VectorBase; SCAU006019-RL; SCAU006019-PL; SCAU006019.
DR   Proteomes; UP000095300; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095300};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095300};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4456   4476       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4651   4669       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4731   4753       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4920   4942       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4996   5019       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       94    148       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      155    200       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      210    264       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      270    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      336    394       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      577    803       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1032   1217       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1447   1667       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      460    480       {ECO:0000256|SAM:Coils}.
FT   COILED     3793   3813       {ECO:0000256|SAM:Coils}.
FT   COILED     4588   4608       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5125 AA;  580695 MW;  0491B489E78D8E3F CRC64;
     MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI ADKNVPPDLS
     QCVFVIEQAL SVRALQELVT AAGSETGKGT GSGHRTLLYG NAILLRHNNS DMYLACLSTS
     SSNDKLSFDV GLQEHSQGEA CWWTVHPASK QRSEGEKVRV GDDLILVSVA TERYLHTTKE
     NEQSIVNASF HVTHWSVQPY GTGISRMKYV GYVFGGDVLR FFHGGDECLT IPSTWGREAG
     QNIVVYEGGS VMSQARSLWR LELARTKWTG GFINWFHPMR IRHITTGRYL GVNENNELIL
     VRKDEASIAT TTFCLRQEKD DEKKVLEDKD LEVIGSPIIK YGDTTVIVQH CETCLWLSYK
     SYETKKKGVG KVEEKQAILH EEGKMDDCLD FSRSQEEESK TARVIRKCSS LFTQFINALE
     TLQSNRRHSV FFQKVNLNEM VMCLEDLINY FSQPPDDMEH EEKQNRFRAL RNRQDLFQEE
     GVLNLILEAI DKINIITSQG FLASFLAGDE TGQSWDLIST YLYQLLAAII QGNHTNCAQF
     ANSNRLNWLF SRLGSQASSE GSGMLDVLHC VLIDSPEALN MMRDEHIKVI ISLLEKHGRD
     PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTQ LVDHVASIRP NIFVGRVANS
     AMYQKWYFEV TMDHIEQTTH MMPHLRIGWA NTSGYVPYPG GGKKWGGNGV GDDLYSFGFD
     GAYLWTGGRK TLVTDMIPEQ PYIRKGDVIG VTIDLSVPII TFTFNGLKVK GCFRDFNLDG
     MFFPVMSCSS KLSCRFLFGG DHGRMKFAPP HGFSPLVQCL MPHQILSLDP CFYFGNLNKN
     VLAGPWMIED DTAFVPNPVD TSGVSLPSSV DQIKEKLAEN IHEMWALNKI EAGWSWGEHR
     DDYQRIHPCL TQFEKLPPAE KRYDNQLAVQ TLKTIIALGY YITMDKPPAR IRPIRLPNEI
     FMQANGYKPA PLDLSAATLT PKLEELVDQL AENTHNLWAR ERIQQGWTYG LNEDSENLRS
     PHLVPYSKVD EAIKKANRDT ASETVRTLLV YGYVLDPPTG EGNEALLAEA LRLKFAAFRT
     YRVERNYAVT SGKWYFEFEV LTAGPMRVGW ARADCNPGAM LGSDDTSWAF DGHNEEKVFG
     GVSESFGKIC GPGDIVGVFL DLADHTISFS LNGELLMDAL GGETTFAEVT AEGVGFVPAC
     TLGVGQKARL IYGQDVDSLK FFTTCGLQEG YEPFCVNMRR PVTHWYTKDQ PIFENTEEMP
     DCRIDVTRIP GGADTPPHLK ISHNTFETME KANWEFLRLS LPVTCMDEFI SEVEKARRWE
     EIKIRQYRLM REAQEMAQHQ PSAHMDHMLK SGFSMNDIKG LNRNYEDTAE ADENMARSPV
     RPARRASITR NITFESDLGM PEELQRSTSA LDMNGMEDGM VDDKKKRGRS PFKFFSKKSR
     DQSKDKTPGR APEVSPERRT GVQGRTMMGG QLAAKPPSLR LNNTEMPQTP TQGPKALSGG
     NLGQPTVESS GNEMFDAECL KLINEYFYGV RIFPGQDPTH VYVGWVTTQY HLHSKEFNKD
     KVRRASVIIE DDYEMPIQHI NRQSCYVVRA DELFNEVTQD ASGKGASQGM FVGCFVDTAT
     GIISFTCEGK QTSHRWQMEP NTKLFPAIFV EATSKEILQI ELGRTATTLP LSAAVLPTSD
     KHINPQSPPR LKVQCLRPHQ WARVPNTALQ VHALKLSDLR GWSMLCEDPV SMLALHIPEE
     DRCIDILELI EMDKLLSFHA HSLTLYAALC YQSNYRAAHA LCQHVDQKQL LYAIRSEYMS
     GPLRQGFYDL LIALHLESHA TTMEVCKMEY IIPLGPELKF LYDDEEMRHS LRSLVTESVR
     PQMRMTEITP MSTQANVSSE PIPDIDHLYS PKFPLEVVRE FVMEALKEAV EINQVHNRDP
     IGWTNENLFL PLVKLTDRLL LVGVMTDDDV QKLLVMIDPE TWDPTFEKDG KDEHRKGLLT
     MKMAEGAKLQ MCYLLHHLYD IQLRHRVESI IAFSHDFVGD LQSDQLRRYI EIKQSDLPSA
     VAAKKTKEFR CPPREQMNQI LCFKNLEPDD HENCTCGLEL RGSLYDFHDS LMKKVSLNAL
     QEPDESESTT IEEIKTGPIT KIYNFINTVK ELEEGPKEVE EPEKKTPEEV FRKVLIKTIV
     SWAEESQIET PKLVREMFSL LVRQYDTVGE LVRALEKTYV INNRARDDVA EMWVGLSQIR
     ALLPVQMSQE EEELMRKRLW KLVNNATFFQ HPDLIRILRI HENVMAVMMN TLGRRAQAQS
     DAPAQQEGGE GAPPKEKDTS HEMVVACCRF LCYFCRTGRQ NQKAMFDHFD FLLDNANILL
     ARPSLRGSTP LDVAYSSLME NTELALALRE HYLEKIAVYL SRCGLQSNSE LVEKGYPDLG
     WDPVEGERYL DFLRYCVWVN GESVEENANL VIRLLIRRPE CLGPALRGEG EGLFRAIVEA
     NRMSERITDR CKMQDEAEGT IAGLNFTHPL PESDDDEDYI DTGAAILNFY CTLVDLLGRC
     APDASVIEQG KNESLRARAI LRSLVPLEDL QGVLSLKFTL TQTAPGEEKP KSDMPSGLLP
     NNKQSIVLFL ERVYGIETQE LFYRLLEDAF LPDLRTATIL DKSDGSESDM ALSMNRYIGN
     SILPLLIKHS KFYNEAENYA SLLDATLHTV YRLSKNRMLT KGQREAVSDF LVALTSQMQP
     AMLLKLLRKL TVDVSKLSEY TTVALRLLTL HFDRCAKYYG SSQGQGSYGA SSDEEKRLTM
     LLFSNIFDSL SNMDYDPELF GKALPCLIAI GCALPPDYSL SKNLDEDYYG RQSGAPDQPQ
     YDPNPIETST VVLTHDYNSL VEKFSEHYHD AWASRRLESG WTYGEVRSDT DRKHPRLKPC
     NMLSDYERER YRDPVRECLK ALLALGWTIE HSEIEVAQNN RGSTRRQSKP QINDFQNEGS
     PFNYNPHPVD MTNLTLSREM QNMAERLAEN SHDIWAKKKK EELGSCGGVI HPQLVPYDLL
     TDKEKRKDRE RSQEFLKYMQ YQGYKLHKPS KGGALEGEGG ATQTAAELRF SYSLLEKLIQ
     YLDRASINMK LLKPSTTFSR RTSFKTASRD IKFFSKVVLP LMEKYFSTHR NYFIAVATAT
     NNVGAASLKE KEMVAAIFCK LASLLRNRLT AFGPDVRITV RCLQVLVKGI DARTLVKNCP
     EFIRTSMLTF FNQTADDLGN TILNLQDGKY SHLRGTHLKT STSLGYINQV VMPVLTAMFD
     HLAACDYGSD LLLDEIQVAS YKILAALYHL GTDGTLTQDR KYLKTEIERH RPALGSCLGA
     FSSCFPVAFF EPHLNKHNQF SLLNRIADHS LEAQDIMVKM ESCMPNLETI LGEVDQFVES
     DKTYSDAPHV IDVILPLLCS YLPFWWSQGP DNVSPTSGNH VTMVTADHMN SLLRNVLNMI
     KKNIGNDNAP WMTRIAAYTQ QIIINTSEEL LKDPFLPLAE RVKKRTENMF HKEESMRGFI
     KSATDDTSQV ETQLQEDWQL LVRDIYSFYP LLIKYVDLQR NHWLKDNIPE AEELYNHVAE
     IFNIWSKSQY FLKEEQNFIS ANEIDNMALI MPTATRRSAI SEGAPVTGGK VKKKKKNRDK
     KRDKDKEIQA SLMVACLKRL LPVGLNLFAG REQELVQHCK DRYLKKMAEY EVIEFARNQL
     TLPDKLDPSD EMSWQHYLYS KLGKKEEPTE EQNALEKAAN QNDKGRDKTQ ETVDRIVAMA
     KVLFGLHMID HPQQQSKNVY RSVVSIQRKR AVIACFRQTS LHSLPRHRAC NIFARTYHEQ
     WLQEENVGQE VMIEDLTQTF EDFEKSKKEE DETEAKPDPL TQLVTTFCRG AMTERSGALQ
     EDLLYMSYAQ IAAKSCGEEE EEGGDEEGGE EEGEGTSIHE QEMEKQKLLF HQARLSNRGV
     AEMVLLHISA SKGIPSEMVM TTLNLGISIL RGGNIDIQMG MLNHLKEKKD VGFFTSIAGL
     MNSCSVLDLD AFERNTKAEE YIPSAGAGLG VGSEGAAGEK NMHDAEFTCA LFRFIQLTCE
     GHNLDWQNYL RTQAGNTTTV NVVICTVDYL LRLQESIMDF YWHYSSKEII DPAGKANFFK
     AIGVASQVFN TLTEVIQGPC TLNQQALAHS RLWDAVGGFL FLFSHMQEKL SKHSSQVDLL
     KELLNLQKDM ITMMLSMLEG NVVNGTIGKQ MVDTLVESAS NVELILKYFD MFLKLKDLIE
     SPSFMEIDIK NEGWVTPKDF RDKMEQSKNY TPEEIDFLLA CCERNHEGKI DYVAFVDRFH
     EPSTEIGFNL AVLLTNLSEH MPNEPRLARF LETAGSVLNY FEPFLGRIEI LGSSKRIERV
     YFEIKDSNIE QWEKPQIKES KRAFFYSIVT EGGDKEKLEA FVNFCEDAIF EMTHASGLMA
     TDDGGSNVKR DTSYSSYMSE EEEERAARDP IRRTITAVKD GLKFGVHMFS PANIKHQIGV
     MQTKTVPELI IGFFKAIFYM FYYTGYAHFA VLRYIFGILM NLMRGPAPEE VEEPPQEEET
     FGRALPPLPI EEPPSTVQAF GLDINKEENG QYKVTVHESS GGSPTSSMEE TGESSPEDGA
     TTAEAGAEGE PHHQEPVSIV DLLGGEAAKK AAQERQEAQK AQEAAMASIE AEAKKSSSTT
     QETPAVNQID FSQYTHRAVS FLARNFYNLK YVALVLAFSI NFMLLFYKVT SFANDEESSG
     DDVLILGSGS GGGMAGSGMG SGDGSGDGGD EEDELPEMVH VDEDFFYMEH VIRMAALLHS
     LVSLAMLIAY YHLKVPLAIF KREKEIARRL EFDGLFIAEQ PEDDDFKSHW DKLVISAKSF
     PVNYWDKFVK KKVRQKYSET YDFDSISNLL GMEKSAFMAQ ESEEGGFVKY ITNIDWRYQV
     WKAGVTFTDN AFLYSLWYFS FSVMGNFNNF FFAAHLLDVA VGFKTLRTIL QSVTHNGKQL
     VLTVMLLTII VYIYTVIAFN FFRKFYIQEE DDEVDKKCHD MLTCFVFHLY KGVRAGGGIG
     DEIGDPVGDE YEVYRIIFDI TFFFFVIVIL LAIIQGLIID AFGELRDQLE SVKENMESNC
     FICGMGKDFF DIVPHGFDTH VQKEHNLANY MFFLMHLINK PDTEYTGQET YVWNMYQQRS
     WDFFPVGDCF RKQYEDELSG GGGGG
//
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