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Database: UniProt
Entry: A0A1I8P9E3_STOCA
LinkDB: A0A1I8P9E3_STOCA
Original site: A0A1I8P9E3_STOCA 
ID   A0A1I8P9E3_STOCA        Unreviewed;      5121 AA.
AC   A0A1I8P9E3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:SCAU006019-PH};
GN   Name=106095874 {ECO:0000313|VectorBase:SCAU006019-PH};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PH};
RN   [1] {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PH}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000095300,
RC   ECO:0000313|VectorBase:SCAU006019-PH};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:SCAU006019-PH}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:SCAU006019-PH};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   RefSeq; XP_013118745.1; XM_013263291.1.
DR   GeneID; 106095874; -.
DR   VectorBase; SCAU006019-RH; SCAU006019-PH; SCAU006019.
DR   Proteomes; UP000095300; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095300};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095300};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4452   4472       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4647   4665       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4727   4749       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4916   4938       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4992   5015       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       98    152       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      159    204       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      214    268       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      274    332       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      340    398       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      581    807       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1036   1221       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1451   1671       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      464    484       {ECO:0000256|SAM:Coils}.
FT   COILED     3797   3817       {ECO:0000256|SAM:Coils}.
FT   COILED     4584   4604       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5121 AA;  580393 MW;  7647FFCD522E99DF CRC64;
     MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI ADKNVPPDLS
     QCVFVIEQAL SVRALQELVT AAGSETDPQF GKGTGSGHRT LLYGNAILLR HNNSDMYLAC
     LSTSSSNDKL SFDVGLQEHS QGEACWWTVH PASKQRSEGE KVRVGDDLIL VSVATERYLH
     TTKENEQSIV NASFHVTHWS VQPYGTGISR MKYVGYVFGG DVLRFFHGGD ECLTIPSTWG
     REAGQNIVVY EGGSVMSQAR SLWRLELART KWTGGFINWF HPMRIRHITT GRYLGVNENN
     ELILVRKDEA SIATTTFCLR QEKDDEKKVL EDKDLEVIGS PIIKYGDTTV IVQHCETCLW
     LSYKSYETKK KGVGKVEEKQ AILHEEGKMD DCLDFSRSQE EESKTARVIR KCSSLFTQFI
     NALETLQSNR RHSVFFQKVN LNEMVMCLED LINYFSQPPD DMEHEEKQNR FRALRNRQDL
     FQEEGVLNLI LEAIDKINII TSQGFLASFL AGDETGQSWD LISTYLYQLL AAIIQGNHTN
     CAQFANSNRL NWLFSRLGSQ ASSEGSGMLD VLHCVLIDSP EALNMMRDEH IKVIISLLEK
     HGRDPKVLDV LCSLCVGNGV AVRSSQNNIC DFLLPGKNLL LQTQLVDHVA SIRPNIFVGR
     VANSAMYQKW YFEVTMDHIE QTTHMMPHLR IGWANTSGYV PYPGGGKKWG GNGVGDDLYS
     FGFDGAYLWT GGRKTLVTDM IPEQPYIRKG DVIGVTIDLS VPIITFTFNG LKVKGCFRDF
     NLDGMFFPVM SCSSKLSCRF LFGGDHGRMK FAPPHGFSPL VQCLMPHQIL SLDPCFYFGN
     LNKNVLAGPW MIEDDTAFVP NPVDTSGVSL PSSVDQIKEK LAENIHEMWA LNKIEAGWSW
     GEHRDDYQRI HPCLTQFEKL PPAEKRYDNQ LAVQTLKTII ALGYYITMDK PPARIRPIRL
     PNEIFMQANG YKPAPLDLSA ATLTPKLEEL VDQLAENTHN LWARERIQQG WTYGLNEDSE
     NLRSPHLVPY SKVDEAIKKA NRDTASETVR TLLVYGYVLD PPTGEGNEAL LAEALRLKFA
     AFRTYRVERN YAVTSGKWYF EFEVLTAGPM RVGWARADCN PGAMLGSDDT SWAFDGHNEE
     KVFGGVSESF GKICGPGDIV GVFLDLADHT ISFSLNGELL MDALGGETTF AEVTAEGVGF
     VPACTLGVGQ KARLIYGQDV DSLKFFTTCG LQEGYEPFCV NMRRPVTHWY TKDQPIFENT
     EEMPDCRIDV TRIPGGADTP PHLKISHNTF ETMEKANWEF LRLSLPVTCM DEFISEVEKA
     RRWEEIKIRQ YRLMREAQEM AQHQPSAHMD HMLKSGFSMN DIKGLNRNYE DTAEADENMA
     RSPVRPARRA SITRNITFES DLGMPEELQR STSALDMNGM EDGMVDDKKK RGRSPFKFFS
     KKSRDQSKDK TPGRAPEVSP ERRTGVQGRT MMGGQLAAKP PSLRLNNTEM PQTPTQGPKA
     LSGGNLGQPT VESSGNEMFD AECLKLINEY FYGVRIFPGQ DPTHVYVGWV TTQYHLHSKE
     FNKDKVRRAS VIIEDDYEMP IQHINRQSCY VVRADELFNE VTQDASGKGA SQGMFVGCFV
     DTATGIISFT CEGKQTSHRW QMEPNTKLFP AIFVEATSKE ILQIELGRTA TTLPLSAAVL
     PTSDKHINPQ SPPRLKVQCL RPHQWARVPN TALQVHALKL SDLRGWSMLC EDPVSMLALH
     IPEEDRCIDI LELIEMDKLL SFHAHSLTLY AALCYQSNYR AAHALCQHVD QKQLLYAIRS
     EYMSGPLRQG FYDLLIALHL ESHATTMEVC KMEYIIPLGP ELKFLYDDEE MRHSLRSLVT
     ESVRPQMRMT EITPMSTQAN VSSEPIPDID HLYSPKFPLE VVREFVMEAL KEAVEINQVH
     NRDPIGWTNE NLFLPLVKLT DRLLLVGVMT DDDVQKLLVM IDPETWDPTF EKDGKDEHRK
     GLLTMKMAEG AKLQMCYLLH HLYDIQLRHR VESIIAFSHD FVGDLQSDQL RRYIEIKQSD
     LPSAVAAKKT KEFRCPPREQ MNQILCFKNL EPDDHENCTC GLELRGSLYD FHDSLMKKVS
     LNALQEPDES ESTTIEEIKT GPITKIYNFI NTVKELEEGP KEVEEPEKKT PEEVFRKVLI
     KTIVSWAEES QIETPKLVRE MFSLLVRQYD TVGELVRALE KTYVINNRAR DDVAEMWVGL
     SQIRALLPVQ MSQEEEELMR KRLWKLVNNA TFFQHPDLIR ILRIHENVMA VMMNTLGRRA
     QAQSDAPAQQ EGGEGAPPKE KDTSHEMVVA CCRFLCYFCR TGRQNQKAMF DHFDFLLDNA
     NILLARPSLR GSTPLDVAYS SLMENTELAL ALREHYLEKI AVYLSRCGLQ SNSELVEKGY
     PDLGWDPVEG ERYLDFLRYC VWVNGESVEE NANLVIRLLI RRPECLGPAL RGEGEGLFRA
     IVEANRMSER ITDRCKMQDE AEGTIAGLNF THPLPESDDD EDYIDTGAAI LNFYCTLVDL
     LGRCAPDASV IEQGKNESLR ARAILRSLVP LEDLQGVLSL KFTLTQTAPG EEKPKSDMPS
     GLLPNNKQSI VLFLERVYGI ETQELFYRLL EDAFLPDLRT ATILDKSDGS ESDMALSMNR
     YIGNSILPLL IKHSKFYNEA ENYASLLDAT LHTVYRLSKN RMLTKGQREA VSDFLVALTS
     QMQPAMLLKL LRKLTVDVSK LSEYTTVALR LLTLHFDRCA KYYGSSQGQG SYGASSDEEK
     RLTMLLFSNI FDSLSNMDYD PELFGKALPC LIAIGCALPP DYSLSKNLDE DYYGRQSGAP
     DQPQYDPNPI ETSTVVLTHD YNSLVEKFSE HYHDAWASRR LESGWTYGEV RSDTDRKHPR
     LKPCNMLSDY ERERYRDPVR ECLKALLALG WTIEHSEIEV AQNNRGSTRR QSKPQINDFQ
     NEGSPFNYNP HPVDMTNLTL SREMQNMAER LAENSHDIWA KKKKEELGSC GGVIHPQLVP
     YDLLTDKEKR KDRERSQEFL KYMQYQGYKL HKPSKGGALE GEGGATQTAA ELRFSYSLLE
     KLIQYLDRAS INMKLLKPST TFSRRTSFKT ASRDIKFFSK VVLPLMEKYF STHRNYFIAV
     ATATNNVGAA SLKEKEMVAA IFCKLASLLR NRLTAFGPDV RITVRCLQVL VKGIDARTLV
     KNCPEFIRTS MLTFFNQTAD DLGNTILNLQ DGKYSHLRGT HLKTSTSLGY INQVVMPVLT
     AMFDHLAACD YGSDLLLDEI QVASYKILAA LYHLGTDGTL TQDRKYLKTE IERHRPALGS
     CLGAFSSCFP VAFFEPHLNK HNQFSLLNRI ADHSLEAQDI MVKMESCMPN LETILGEVDQ
     FVESDKTYSD APHVIDVILP LLCSYLPFWW SQGPDNVSPT SGNHVTMVTA DHMNSLLRNV
     LNMIKKNIGN DNAPWMTRIA AYTQQIIINT SEELLKDPFL PLAERVKKRT ENMFHKEESM
     RGFIKSATDD TSQVETQLQE DWQLLVRDIY SFYPLLIKYV DLQRNHWLKD NIPEAEELYN
     HVAEIFNIWS KSQYFLKEEQ NFISANEIDN MALIMPTATR RSAISEGAPV TGGKVKKKKK
     NRDKKRDKDK EIQASLMVAC LKRLLPVGLN LFAGREQELV QHCKDRYLKK MAEYEVIEFA
     RNQLTLPDKL DPSDEMSWQH YLYSKLGKKE EPTEEQNALE KAANQNDKGR DKTQETVDRI
     VAMAKVLFGL HMIDHPQQQS KNVYRSVVSI QRKRAVIACF RQTSLHSLPR HRACNIFART
     YHEQWLQEEN VGQEVMIEDL TQTFEDFEKS KKEEDETEAK PDPLTQLVTT FCRGAMTERS
     GALQEDLLYM SYAQIAAKSC GEEEEEGGDE EGGEEEGEGT SIHEQEMEKQ KLLFHQARLS
     NRGVAEMVLL HISASKGIPS EMVMTTLNLG ISILRGGNID IQMGMLNHLK EKKDVGFFTS
     IAGLMNSCSV LDLDAFERNT KAEGLGVGSE GAAGEKNMHD AEFTCALFRF IQLTCEGHNL
     DWQNYLRTQA GNTTTVNVVI CTVDYLLRLQ ESIMDFYWHY SSKEIIDPAG KANFFKAIGV
     ASQVFNTLTE VIQGPCTLNQ QALAHSRLWD AVGGFLFLFS HMQEKLSKHS SQVDLLKELL
     NLQKDMITMM LSMLEGNVVN GTIGKQMVDT LVESASNVEL ILKYFDMFLK LKDLIESPSF
     MEIDIKNEGW VTPKDFRDKM EQSKNYTPEE IDFLLACCER NHEGKIDYVA FVDRFHEPST
     EIGFNLAVLL TNLSEHMPNE PRLARFLETA GSVLNYFEPF LGRIEILGSS KRIERVYFEI
     KDSNIEQWEK PQIKESKRAF FYSIVTEGGD KEKLEAFVNF CEDAIFEMTH ASGLMATDDG
     GSNVKRDTSY SSYMSEEEEE RAARDPIRRT ITAVKDGLKF GVHMFSPANI KHQIGVMQTK
     TVPELIIGFF KAIFYMFYYT GYAHFAVLRY IFGILMNLMR GPAPEEVEEP PQEEETFGRA
     LPPLPIEEPP STVQAFGLDI NKEENGQYKV TVHESSGGSP TSSMEETGES SPEDGATTAE
     AGAEGEPHHQ EPVSIVDLLG GEAAKKAAQE RQEAQKAQEA AMASIEAEAK KSSSTTQETP
     AVNQIDFSQY THRAVSFLAR NFYNLKYVAL VLAFSINFML LFYKVTSFAN DEESSGDDVL
     ILGSGSGGGM AGSGMGSGDG SGDGGDEEDE LPEMVHVDED FFYMEHVIRM AALLHSLVSL
     AMLIAYYHLK VPLAIFKREK EIARRLEFDG LFIAEQPEDD DFKSHWDKLV ISAKSFPVNY
     WDKFVKKKVR QKYSETYDFD SISNLLGMEK SAFMAQESEE GGFVKYITNI DWRYQVWKAG
     VTFTDNAFLY SLWYFSFSVM GNFNNFFFAA HLLDVAVGFK TLRTILQSVT HNGKQLVLTV
     MLLTIIVYIY TVIAFNFFRK FYIQEEDDEV DKKCHDMLTC FVFHLYKGVR AGGGIGDEIG
     DPVGDEYEVY RIIFDITFFF FVIVILLAII QGLIIDAFGE LRDQLESVKE NMESNCFICG
     MGKDFFDIVP HGFDTHVQKE HNLANYMFFL MHLINKPDTE YTGQETYVWN MYQQRSWDFF
     PVGDCFRKQY EDELSGGGGG G
//
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