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Database: UniProt
Entry: A0A1I8P9L3_STOCA
LinkDB: A0A1I8P9L3_STOCA
Original site: A0A1I8P9L3_STOCA 
ID   A0A1I8P9L3_STOCA        Unreviewed;      5103 AA.
AC   A0A1I8P9L3;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-FEB-2018, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|VectorBase:SCAU006019-PI};
GN   Name=106095874 {ECO:0000313|VectorBase:SCAU006019-PI};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha;
OC   Muscoidea; Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PI};
RN   [1] {ECO:0000313|Proteomes:UP000095300, ECO:0000313|VectorBase:SCAU006019-PI}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=USDA {ECO:0000313|Proteomes:UP000095300,
RC   ECO:0000313|VectorBase:SCAU006019-PI};
RA   Wang D.B., Wang M.;
RL   Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|VectorBase:SCAU006019-PI}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|VectorBase:SCAU006019-PI};
RG   VectorBase;
RL   Submitted (NOV-2016) to UniProtKB.
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DR   RefSeq; XP_013118754.1; XM_013263300.1.
DR   GeneID; 106095874; -.
DR   VectorBase; SCAU006019-RI; SCAU006019-PI; SCAU006019.
DR   Proteomes; UP000095300; Genome assembly.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000095300};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000095300};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4434   4454       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4629   4647       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4709   4731       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4898   4920       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4974   4997       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       94    148       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      155    200       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      210    264       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      270    328       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      336    394       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      577    803       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1032   1217       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1447   1667       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   COILED      460    480       {ECO:0000256|SAM:Coils}.
FT   COILED     3779   3799       {ECO:0000256|SAM:Coils}.
FT   COILED     4566   4586       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   5103 AA;  578398 MW;  052ED6FB3896F96F CRC64;
     MAEAEGGSEQ DDVSFLRTED MVCLSCTATG ERVCLAAEGF GNRHCFLENI ADKNVPPDLS
     QCVFVIEQAL SVRALQELVT AAGSETGKGT GSGHRTLLYG NAILLRHNNS DMYLACLSTS
     SSNDKLSFDV GLQEHSQGEA CWWTVHPASK QRSEGEKVRV GDDLILVSVA TERYLHTTKE
     NEQSIVNASF HVTHWSVQPY GTGISRMKYV GYVFGGDVLR FFHGGDECLT IPSTWGREAG
     QNIVVYEGGS VMSQARSLWR LELARTKWTG GFINWFHPMR IRHITTGRYL GVNENNELIL
     VRKDEASIAT TTFCLRQEKD DEKKVLEDKD LEVIGSPIIK YGDTTVIVQH CETCLWLSYK
     SYETKKKGVG KVEEKQAILH EEGKMDDCLD FSRSQEEESK TARVIRKCSS LFTQFINALE
     TLQSNRRHSV FFQKVNLNEM VMCLEDLINY FSQPPDDMEH EEKQNRFRAL RNRQDLFQEE
     GVLNLILEAI DKINIITSQG FLASFLAGDE TGQSWDLIST YLYQLLAAII QGNHTNCAQF
     ANSNRLNWLF SRLGSQASSE GSGMLDVLHC VLIDSPEALN MMRDEHIKVI ISLLEKHGRD
     PKVLDVLCSL CVGNGVAVRS SQNNICDFLL PGKNLLLQTQ LVDHVASIRP NIFVGRVANS
     AMYQKWYFEV TMDHIEQTTH MMPHLRIGWA NTSGYVPYPG GGKKWGGNGV GDDLYSFGFD
     GAYLWTGGRK TLVTDMIPEQ PYIRKGDVIG VTIDLSVPII TFTFNGLKVK GCFRDFNLDG
     MFFPVMSCSS KLSCRFLFGG DHGRMKFAPP HGFSPLVQCL MPHQILSLDP CFYFGNLNKN
     VLAGPWMIED DTAFVPNPVD TSGVSLPSSV DQIKEKLAEN IHEMWALNKI EAGWSWGEHR
     DDYQRIHPCL TQFEKLPPAE KRYDNQLAVQ TLKTIIALGY YITMDKPPAR IRPIRLPNEI
     FMQANGYKPA PLDLSAATLT PKLEELVDQL AENTHNLWAR ERIQQGWTYG LNEDSENLRS
     PHLVPYSKVD EAIKKANRDT ASETVRTLLV YGYVLDPPTG EGNEALLAEA LRLKFAAFRT
     YRVERNYAVT SGKWYFEFEV LTAGPMRVGW ARADCNPGAM LGSDDTSWAF DGHNEEKVFG
     GVSESFGKIC GPGDIVGVFL DLADHTISFS LNGELLMDAL GGETTFAEVT AEGVGFVPAC
     TLGVGQKARL IYGQDVDSLK FFTTCGLQEG YEPFCVNMRR PVTHWYTKDQ PIFENTEEMP
     DCRIDVTRIP GGADTPPHLK ISHNTFETME KANWEFLRLS LPVTCMDEFI SEVEKARRWE
     EIKIRQYRLM REAQEMAQHQ PSAHMDHMLK SGFSMNDIKG LNRNYEDTAE ADENMARSPV
     RPARRASITR NITFESDLGM PEELQRSTSA LDMNGMEDGM VDDKKKRGRS PFKFFSKKSR
     DQSKDKTPGR APEVSPERRT GVQGRTMMGG QLAAKPPSLR LNNTEMPQTP TQGPKALSGG
     NLGQPTVESS GNEMFDAECL KLINEYFYGV RIFPGQDPTH VYVGWVTTQY HLHSKEFNKD
     KVRRASVIIE DDYEMPIQHI NRQSCYVVRA DELFNEVTQD ASGKGASQGM FVGCFVDTAT
     GIISFTCEGK QTSHRWQMEP NTKLFPAIFV EATSKEILQI ELGRTATTLP LSAAVLPTSD
     KHINPQSPPR LKVQCLRPHQ WARVPNTALQ VHALKLSDLR GWSMLCEDPV SMLALHIPEE
     DRCIDILELI EMDKLLSFHA HSLTLYAALC YQSNYRAAHA LCQHVDQKQL LYAIRSEYMS
     GPLRQGFYDL LIALHLESHA TTMEVCKMEY IIPLGPELKF LYDDEEMRHS LRSLVTESVR
     PQMRMTEITE PIPDIDHLYS PKFPLEVVRE FVMEALKEAV EINQVHNRDP IGWTNENLFL
     PLVKLTDRLL LVGVMTDDDV QKLLVMIDPE TWDPTFEKDG KDEHRKGLLT MKMAEGAKLQ
     MCYLLHHLYD IQLRHRVESI IAFSHDFVGD LQSDQLRRYI EIKQSDLPSA VAAKKTKEFR
     CPPREQMNQI LCFKNLEPDD HENCTCGLEL RGSLYDFHDS LMKKVSLNAL QEPDESESTT
     IEEIKTGPIT KIYNFINTVK ELEEGPKEVE EPEKKTPEEV FRKVLIKTIV SWAEESQIET
     PKLVREMFSL LVRQYDTVGE LVRALEKTYV INNRARDDVA EMWVGLSQIR ALLPVQMSQE
     EEELMRKRLW KLVNNATFFQ HPDLIRILRI HENVMAVMMN TLGRRAQAQS DAPAQQEGGE
     GAPPKEKDTS HEMVVACCRF LCYFCRTGRQ NQKAMFDHFD FLLDNANILL ARPSLRGSTP
     LDVAYSSLME NTELALALRE HYLEKIAVYL SRCGLQSNSE LVEKGYPDLG WDPVEGERYL
     DFLRYCVWVN GESVEENANL VIRLLIRRPE CLGPALRGEG EGLFRAIVEA NRMSERITDR
     CKMQDEAEGT IAGLNFTHPL PESDDDEDYI DTGAAILNFY CTLVDLLGRC APDASVIEQG
     KNESLRARAI LRSLVPLEDL QGVLSLKFTL TQTAPGEEKP KSDMPSGLLP NNKQSIVLFL
     ERVYGIETQE LFYRLLEDAF LPDLRTATIL DKSDGSESDM ALSMNRYIGN SILPLLIKHS
     KFYNEAENYA SLLDATLHTV YRLSKNRMLT KGQREAVSDF LVALTSQMQP AMLLKLLRKL
     TVDVSKLSEY TTVALRLLTL HFDRCAKYYG SSQGQGSYGA SSDEEKRLTM LLFSNIFDSL
     SNMDYDPELF GKALPCLIAI GCALPPDYSL SKNLDEDYYG RQSGAPDQPQ YDPNPIETST
     VVLTHDYNSL VEKFSEHYHD AWASRRLESG WTYGEVRSDT DRKHPRLKPC NMLSDYERER
     YRDPVRECLK ALLALGWTIE HSEIEVAQNN RGSTRRQSKP QINEGSPFNY NPHPVDMTNL
     TLSREMQNMA ERLAENSHDI WAKKKKEELG SCGGVIHPQL VPYDLLTDKE KRKDRERSQE
     FLKYMQYQGY KLHKPSKGGA LEGEGGATQT AAELRFSYSL LEKLIQYLDR ASINMKLLKP
     STTFSRRTSF KTASRDIKFF SKVVLPLMEK YFSTHRNYFI AVATATNNVG AASLKEKEMV
     AAIFCKLASL LRNRLTAFGP DVRITVRCLQ VLVKGIDART LVKNCPEFIR TSMLTFFNQT
     ADDLGNTILN LQDGKYSHLR GTHLKTSTSL GYINQVVMPV LTAMFDHLAA CDYGSDLLLD
     EIQVASYKIL AALYHLGTDG TLTQDRKYLK TEIERHRPAL GSCLGAFSSC FPVAFFEPHL
     NKHNQFSLLN RIADHSLEAQ DIMVKMESCM PNLETILGEV DQFVESDKTY SDAPHVIDVI
     LPLLCSYLPF WWSQGPDNVS PTSGNHVTMV TADHMNSLLR NVLNMIKKNI GNDNAPWMTR
     IAAYTQQIII NTSEELLKDP FLPLAERVKK RTENMFHKEE SMRGFIKSAT DDTSQVETQL
     QEDWQLLVRD IYSFYPLLIK YVDLQRNHWL KDNIPEAEEL YNHVAEIFNI WSKSQYFLKE
     EQNFISANEI DNMALIMPTA TRRSAISEGA PVTGGKVKKK KKNRDKKRDK DKEIQASLMV
     ACLKRLLPVG LNLFAGREQE LVQHCKDRYL KKMAEYEVIE FARNQLTLPD KLDPSDEMSW
     QHYLYSKLGK KEEPTEEQNA LEKAANQNDK GRDKTQETVD RIVAMAKVLF GLHMIDHPQQ
     QSKNVYRSVV SIQRKRAVIA CFRQTSLHSL PRHRACNIFA RTYHEQWLQE ENVGQEVMIE
     DLTQTFEDFE KSKKEEDETE AKPDPLTQLV TTFCRGAMTE RSGALQEDLL YMSYAQIAAK
     SCGEEEEEGG DEEGGEEEGE GTSIHEQEME KQKLLFHQAR LSNRGVAEMV LLHISASKGI
     PSEMVMTTLN LGISILRGGN IDIQMGMLNH LKEKKDVGFF TSIAGLMNSC SVLDLDAFER
     NTKAEGLGVG SEGAAGEKNM HDAEFTCALF RFIQLTCEGH NLDWQNYLRT QAGNTTTVNV
     VICTVDYLLR LQESIMDFYW HYSSKEIIDP AGKANFFKAI GVASQVFNTL TEVIQGPCTL
     NQQALAHSRL WDAVGGFLFL FSHMQEKLSK HSSQVDLLKE LLNLQKDMIT MMLSMLEGNV
     VNGTIGKQMV DTLVESASNV ELILKYFDMF LKLKDLIESP SFMEIDIKNE GWVTPKDFRD
     KMEQSKNYTP EEIDFLLACC ERNHEGKIDY VAFVDRFHEP STEIGFNLAV LLTNLSEHMP
     NEPRLARFLE TAGSVLNYFE PFLGRIEILG SSKRIERVYF EIKDSNIEQW EKPQIKESKR
     AFFYSIVTEG GDKEKLEAFV NFCEDAIFEM THASGLMATD DGGSNVKRDT SYSSYMSEEE
     EERAARDPIR RTITAVKDGL KFGVHMFSPA NIKHQIGVMQ TKTVPELIIG FFKAIFYMFY
     YTGYAHFAVL RYIFGILMNL MRGPAPEEVE EPPQEEETFG RALPPLPIEE PPSTVQAFGL
     DINKEENGQY KVTVHESSGG SPTSSMEETG ESSPEDGATT AEAGAEGEPH HQEPVSIVDL
     LGGEAAKKAA QERQEAQKAQ EAAMASIEAE AKKSSSTTQE TPAVNQIDFS QYTHRAVSFL
     ARNFYNLKYV ALVLAFSINF MLLFYKVTSF ANDEESSGDD VLILGSGSGG GMAGSGMGSG
     DGSGDGGDEE DELPEMVHVD EDFFYMEHVI RMAALLHSLV SLAMLIAYYH LKVPLAIFKR
     EKEIARRLEF DGLFIAEQPE DDDFKSHWDK LVISAKSFPV NYWDKFVKKK VRQKYSETYD
     FDSISNLLGM EKSAFMAQES EEGGFVKYIT NIDWRYQVWK AGVTFTDNAF LYSLWYFSFS
     VMGNFNNFFF AAHLLDVAVG FKTLRTILQS VTHNGKQLVL TVMLLTIIVY IYTVIAFNFF
     RKFYIQEEDD EVDKKCHDML TCFVFHLYKG VRAGGGIGDE IGDPVGDEYE VYRIIFDITF
     FFFVIVILLA IIQGLIIDAF GELRDQLESV KENMESNCFI CGMGKDFFDI VPHGFDTHVQ
     KEHNLANYMF FLMHLINKPD TEYTGQETYV WNMYQQRSWD FFPVGDCFRK QYEDELSGGG
     GGG
//
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