ID A0A1I8PEK4_STOCA Unreviewed; 297 AA.
AC A0A1I8PEK4;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE RecName: Full=Pleckstrin homology domain-containing family F member 2 {ECO:0008006|Google:ProtNLM};
GN Name=106095670 {ECO:0000313|EnsemblMetazoa:SCAU007320-PB};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU007320-PB, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU007320-PB}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU007320-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013118412.1; XM_013262958.1.
DR RefSeq; XP_013118413.1; XM_013262959.1.
DR AlphaFoldDB; A0A1I8PEK4; -.
DR STRING; 35570.A0A1I8PEK4; -.
DR EnsemblMetazoa; SCAU007320-RA; SCAU007320-PA; SCAU007320.
DR EnsemblMetazoa; SCAU007320-RB; SCAU007320-PB; SCAU007320.
DR GeneID; 106095670; -.
DR KEGG; scac:106095670; -.
DR VEuPathDB; VectorBase:SCAU007320; -.
DR OrthoDB; 5385125at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15717; FYVE_PKHF; 1.
DR CDD; cd01218; PH_Phafin2-like; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037871; PH_Phafin.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46280:SF3; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 HOMOLOG; 1.
DR PANTHER; PTHR46280; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 35..131
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 152..212
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 219..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 219..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..297
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 297 AA; 32988 MW; 7FC58783FC7E63ED CRC64;
MVDRLVNSEA NTRRIATVEN CFGSSGVALA IPGRVLVGEG VLTKMCRKRP KSRQFFLFND
ILVYGNIVIG KKKYNKQHIM PLEEVSLENI DDCTQYRNGW LIRTTTKSFV VCAATPTEKQ
EWMAHINKCV EDLLRKSGKK PVENHAAVWV PDAEANVCMH CKKTQFTMIV RRHHCRNCGA
VVCGPCSSKK FLLPQQSSKP QRVCSSCYDR LSKVVKQESA KMSSNSLNSS AHNDSQNNAN
ESSGEDDSDD EGNGIGNEQH DEPKFYGDTS ILSSTETNSA TNTTNNTHVN SSHTPNN
//
