ID A0A1I8PJ33_STOCA Unreviewed; 651 AA.
AC A0A1I8PJ33;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=T-box domain-containing protein {ECO:0000259|PROSITE:PS50252};
GN Name=106084756 {ECO:0000313|EnsemblMetazoa:SCAU008577-PD};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU008577-PD, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU008577-PD}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU008577-PD};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00201}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00201}.
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DR RefSeq; XP_013104120.1; XM_013248666.1.
DR AlphaFoldDB; A0A1I8PJ33; -.
DR EnsemblMetazoa; SCAU008577-RD; SCAU008577-PD; SCAU008577.
DR GeneID; 106084756; -.
DR VEuPathDB; VectorBase:SCAU008577; -.
DR OrthoDB; 5323209at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd20192; T-box_TBXT_TBX19-like; 1.
DR Gene3D; 2.60.40.820; Transcription factor, T-box; 1.
DR InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR InterPro; IPR046360; T-box_DNA-bd.
DR InterPro; IPR036960; T-box_sf.
DR InterPro; IPR002070; TF_Brachyury.
DR InterPro; IPR001699; TF_T-box.
DR InterPro; IPR018186; TF_T-box_CS.
DR PANTHER; PTHR11267; T-BOX PROTEIN-RELATED; 1.
DR PANTHER; PTHR11267:SF106; T-RELATED PROTEIN; 1.
DR Pfam; PF00907; T-box; 1.
DR PRINTS; PR00938; BRACHYURY.
DR PRINTS; PR00937; TBOX.
DR SMART; SM00425; TBOX; 1.
DR SUPFAM; SSF49417; p53-like transcription factors; 1.
DR PROSITE; PS01283; TBOX_1; 1.
DR PROSITE; PS01264; TBOX_2; 1.
DR PROSITE; PS50252; TBOX_3; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00201};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00201}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 56..229
FT /note="T-box"
FT /evidence="ECO:0000259|PROSITE:PS50252"
FT REGION 1..44
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 276..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 387..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..352
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 651 AA; 70528 MW; FAAF3C0944A63D16 CRC64;
MQDMSTSHIL SAVDPHTNGT HSPQHLHTDG MVNNNHNAMG NRGSPNALER NLHVSLDDRE
LWLRFQNLTN EMIVTKNGRR MFPVVKISAS GLDPAAMYTV LLEFVQVDTH RWKYVNGEWV
PGGKAEVPPS NPIYVHPESP NFGAHWMKEP ISFAKVKLTN KTNGNGQIML NSLHKYEPRV
HLVRVGSEQR HVVTYPFPET QFIAVTAYQN EEVTSLKIKY NPFAKAFLDA KRPDTLYSHD
AHYGWLIPPP THYTTSPVNP NGLSESSLVS SNCDRYGRAL PSRATPSQRS TPYSRPRIVS
GSASNGSTGN ASPPQPPSAP QTPTSLQSSS TATLGTSATS SGFSSSYSQS GFMPVEPTSS
ATVFSYPGTW QTNTNYWSST AVPGPMPVNT ARAMSSHNSP SPTNNGSPTY TTPSPGYTIH
HLTPHTHTHH QYNMPQTAAA HTADMYQSVS PTTQSYAPTH QVYHPTPTSP SSHQLYSNVL
NGPSALSYPT SSWHNGSAAD YGLYQNPAAA YAYQTEYIPL VSEIGLVTND SFLHYQQSSS
YVPPALEPVE VTKTLDNTSH SALYRATEEP TTVLTLECNS LKADSHPLSS HVVENSVKME
SLNAAANGGG GHMRAASVDA ATASAVVTAP VPSADNSANW TPLTPPQSAL Q
//
