ID A0A1I8PKJ1_STOCA Unreviewed; 561 AA.
AC A0A1I8PKJ1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=TGF-beta family profile domain-containing protein {ECO:0000259|PROSITE:PS51362};
GN Name=106091824 {ECO:0000313|EnsemblMetazoa:SCAU008891-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU008891-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU008891-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU008891-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR RefSeq; XP_013113953.1; XM_013258499.1.
DR AlphaFoldDB; A0A1I8PKJ1; -.
DR STRING; 35570.A0A1I8PKJ1; -.
DR EnsemblMetazoa; SCAU008891-RA; SCAU008891-PA; SCAU008891.
DR GeneID; 106091824; -.
DR KEGG; scac:106091824; -.
DR VEuPathDB; VectorBase:SCAU008891; -.
DR OrthoDB; 3015718at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13752; TGF_beta_INHB; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR001111; TGF-b_propeptide.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF294; DAWDLE, ISOFORM A; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR Pfam; PF00688; TGFb_propeptide; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354}; Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..561
FT /note="TGF-beta family profile domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5009326811"
FT DOMAIN 439..561
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 55..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..78
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 65549 MW; F9DC284090627DEC CRC64;
MAKYFLTFVL LAFLAMENNN IYNRLHAKSQ HSSDSNAVVH YMRQQYQYRQ HAQPLTNHHP
THDHHKTHHA RKHVKQHQRH NSDNKEEEKI SRRYGERIKR HMKQQMEHHK EHDQLLQDRQ
RDRTVYNRET LRAMPRLWQH LSTAYDYGTG EDDINEDQTV FGGESVNESQ EYPNDGDILN
TDTALLEHDE KITDIVEPQK PAHIGCPKCE SSRNEDMISE EELTRLRIEY VKQQILDKLG
LKEKPNIPAV SLPKPILEGQ TIQKEDDDSS KKDMDDYYAR TSKKFIFLEV EKEECQKLES
QPSMCFSFKL DDTDADNYEV RTAVLWIFKN KHQNSTNSRN HTLLAENQQK IIVSEVQQET
TSNRKPAVKT IAAQTVDVQD EWIKIDIEWP IKRWFGNHEL NHLIQITCQS CDMTAMDHII
STEKDYRPFI MVNTQSRKRQ TRQKRNINCT HGVTECCREK LYISFADIGW SDWIAAPEGY
DAYFCRGSCN TVASVANSGS QHSTFLQKLL NKPGQRRKNL EMVPCCTAKK YSSLQLLLVQ
NITASREMIL PNMVVESCGC R
//
