ID A0A1I8PMF7_STOCA Unreviewed; 8839 AA.
AC A0A1I8PMF7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Dystonin {ECO:0008006|Google:ProtNLM};
GN Name=106087979 {ECO:0000313|EnsemblMetazoa:SCAU009413-PAK};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU009413-PAK, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU009413-PAK}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU009413-PAK};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_013108693.1; XM_013253239.1.
DR EnsemblMetazoa; SCAU009413-RAK; SCAU009413-PAK; SCAU009413.
DR VEuPathDB; VectorBase:SCAU009413; -.
DR OrthoDB; 5489926at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21189; CH_PLEC-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 17.
DR Gene3D; 1.20.58.60; -; 32.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 12.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF23; SHORT STOP, ISOFORM H; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 16.
DR Pfam; PF21020; Spectrin_4; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00250; PLEC; 30.
DR SMART; SM00150; SPEC; 37.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF75399; Plakin repeat; 16.
DR SUPFAM; SSF46966; Spectrin repeat; 34.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 271..376
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 922..980
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 8436..8471
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8472..8507
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8512..8584
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 2926..2945
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3009..3083
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3118..3193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3215..3266
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3300..3504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3581..3605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5634..5693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 7066..7101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8281..8375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8607..8839
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 497..571
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1062..1089
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6019..6046
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6426..6479
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6563..6590
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6883..6910
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 3027..3053
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3132..3152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3153..3182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3232..3256
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3308..3359
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3400..3419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3429..3478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3581..3604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5670..5693
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7066..7087
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8312..8326
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8327..8349
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8350..8364
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8607..8634
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8650..8826
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8839 AA; 995920 MW; F95C8C496CC29AE2 CRC64;
MYKIDKNFGT GHNNRICLRG GTSAAPPSPT QLCGGALAMH STTTSKASSL MKKHGSGYGS
SMSKALVPSR GPAITTNIDE KSAQFQHQFK HEKTIEAVIT DYPGIAPESA TPHERMSYDR
SIVLRKSFRN GGAHDTTNLT NAVAIVPAAN QHHAMHESYQ QVTRNKRVST EILGSSVEST
KTSQRGPSGH RRITTHIVRK VTTLSRAEEQ QLAPEDLLPP AKMVRSSDLE YRHTLPRTAV
VVPAIEPASS STTTIRRTKI SDIVVGKEDN VSAREALLRW ARRSTARYPG VRVNDFTSSW
RDGLAFSALV HRNRPDLLDW RKARNDRPRE RLENAFHIVE KEYGVTRLLD PEDVDTNEPD
EKSLITYISS LYDVFPEPPS IHPLYDMESQ RRVHEYRDLA KQFISWCREK TAYLQDRSFP
PNLIELKRLL GDLHSFGSDE VSARKREKSK LVQIYKELER YFEIVGEIDV EAELRPEAIE
KAWYRMQTAL QDRDMILQQE IERLERLQRL ADKVQREIKH VDMKITDLET RITEEARHIE
TLHPVNAKNI VESLETEIRH LEEPIQEMNQ DCHILNEGRY THAAELHKKV NKLHQRWAQL
RTTFHTVLVQ KLSGLKYPVH EKTTTRQQRV VVESRQIETN PYFRDLQEHI EWCQNKLKQL
LAADYGSDLP SVKKELDRQQ HEHKDIDQFH SKILKDEHQQ TKFSGDELTL YQQRLNQLQK
VYAELLSTST KRLSDLDTLQ HFLAQASAEL QWLNEKEQIE ITRDWADKNL DLSSVHRYYE
NLMSELEKRE LHFGTILDRG ETLLNQHHPA SKCIEAHLTA LQQQWAWLLQ LTLCLEVHLK
HATEYHQFFA EIKDAEQWLS KRDEILNSEY SKSEFGLDQG ETLLRGMQDL REELNAFGDT
VATLQLRAQT IVPLNKRRQP VNRQSPVQAI CAYNQQGQIP VEKGETCTLM DNSGRVKWRV
RTTKGQEGLV PSACLLMPPP DKEAIDAAER LKRLFDRSVS LWQKKHLRLR QNMIFATIRV
VKDWDFEQFL AMGPEQRTAI RRALNDDADK LLSEGDPNDP QLRRLKREMD EVNRLFDEFE
KRARAEEESK QASRIFTEEC ITIKGKLEDM ARELEQIISA PLPRDLDSLE HVLEIHSDYE
RRLQLLEPEL QHLQETFRTI ALKTPALKKS LDNLMILWKE LNTLSNLHKD RLKLLEASLA
GLEDNEHFIS EIENQLAKHQ DLPSTPERLE MVFKQLTHMQ DLITQQQPQM DKMTDAADQL
GRMGVPTKVL GDLKRLHANV ERLNTRWSSI CNQLAERMRS CENAIGLMKN LQSSVQVEES
WVDGTTERLS AMPTATSAYE LDKLLGAAIE RKPKIENVNL AGGKLIREAK IYDGKCMRFI
DWLLEVRPSF SPPRRDLRPA DSDPGATQYY SQRLDILNTK YDRLLEQLSQ RLKTAIEVNG
SDGLQYAESL QKPLKTFRVD FSNANNVPTG EGYVARDADL FTTTYSTTQF STTKTTKSVY
DATDYVHTTT TTNGTAGPVP ATTSKQSQIQ FNEIHSLKRV QTKNENVGTT TTTEFVGGTN
VKHLLDMTGI RDPRTGRVLT IGDAIQMRLL DVRTGEMLVG DKRISLEEAV KQGLIDAKLA
HQLLQPGAAR DGRDGRELSL LEVIQREITE AETGYETAEK RIKVTVDESP DAENPKNIAD
AISAGNVDTK TGLYRVKSGK TITLAEAYER GYLIRHESVT IKSNALCLSD AIAHGLVDTA
GWIADRNSGD KFRLDSAIAN QLIDPNIREV VDAKRDIKIT LTEALNSGIL NPKTGRYWNE
VTKEKLTFIE AKNRQLIVKP YTLKDICDLN LLDKQSMITS PMRREKLSIM QAIESGVLDG
NNLKCITKRK GELVTLQEAI ADGIVLPAES RYRDYMTSEV LSIPEAVERG LISSVSQKSI
FDIDGFKDMR SNDFVSFNVA LSRGILRRKS NGFALETSRD TQVPLEVALN EGLIRPEVYE
MFNKGIGVHN ASGKELSVFD LCYHSLIDPK TGYLLDPKAE ETVPLDLAIE RKFITPEGAL
LLSSLLNITL TTETVTRTIN RYVTIRASSQ EPLETTIVLT FTEALRQGFI DEERQLFKDP
KTGNIYSVQQ ALSYGLLQPD ANETVPEPTN RKKTKSTITI VTKQIVPESE PIKLNTQNFI
EKSVEIPIAE EVRKPGKIST DFIQSEKTSY VQQNVRERQI IEFPPGGWPL KDAIEQQLFN
PDTGVFHIKN TERAVTFEEC INKYIINSLS VSVIDPRTGE KLSIRNAFER DIIDSYGSYT
NTNDDVETMR SAIGQGKIIL EHVPSTKTSA REQCILRVSK INNLPEIVEI STPLLSGSSQ
KFVEVRTVQR ELTSPEPLQI APGAIYDPST ALVIFTHNGQ TENIFDAARH GLIDESLIRI
VDPQTKEVIS ISEALARNIY DPQNGTILTD DTYAVDILTA IQKGLIVVAG APLVAAEGAL
RTIRFVTDPR TGEQIPVEVA YERGIVSRDQ LRKTKSVESD ASEDKVVVLQ KMRKMILKPD
DAFKKGIIDV VARDILENKD NFLGDNNEVL NITEALQRGQ IDGSKGKIAD PQRNRFLNIS
EAVKERVIDP EETNHILIPL AQSLSIPKLM EQGLVDTKTQ TIVHPESGYG LNIREAIVCD
VLDQYSKLKR PIKCTLEEAI EKHIVDPDES TFNVNGKVLT LAQAVNADIF EKTSDKVKPL
VPIPPVGMTF PVVVEKGLLK PENVSVIHPE SRKEIPLKKA IEEGFIMSIP YPPQADAMEV
HHAVQQGLIN IVDQTFRHPK DNGQATPLRP ALETGRLVVK PISDFVVTQQ PVARTEIMET
ITAVHTVTTK TIELVQGYVL ISNNEVQNIK TGEVWTIEEA KAKGILKEEE TSKESRSVTG
NKDNIEELLQ QPNTEDQTTI SERVIQNTTK NKNLIVTQQG TIQMEGHPMP TPGQPMPGQE
TPKQDSKLSA TLNNVKEAAK MGALGIVAAP VLAGGALVSG IKQLVKTSTT TTTTTEFNDE
TQKVISTSAT LGAVETNDKF PRETAPSPHN PNGSHASSSM TTTITSTVPQ QPGITKDAPK
PPTQDSAQSD DVLPHLKDSK TKATDVHTID NLMKDTENFI NTTTANFINQ EKNVEGQHLP
KTGVHSPADA TRSLEGNDNL QVKPSDQITS ALSHEEPNKK SKDRTPSDKD RTVDKDRPLQ
EASDNATNKG VSSNVIITTE MSATTTDPIN EIVEVSETTG QPKDRKPSSG DLESSKGNQT
TTTTTTTITT SKITKGEGFE PSEGVPSLTE ASLKGIVDDK HPQKYGVVTD FIKHETNVLH
RPEESLASPS GLKSQLVDGS LQSDKPESDK PQLIGQTTRT TTTTTITTTT EQVGQFNAPL
QPFSEDVETD LESFGGDKSQ QDSPNNKQGE KPKDGSLPAN LLKSGQTPPS SILTEETTQK
HPSTMDKSEN DESQQFNNAS TAPQVASGEK SPVSATDVST IVKSTHGEDP QTFTPLDTKD
KPSLAARKST DKLGDLTQPQ NATDDPHRRV VDFIQAEKGD HTAGNVLQNV KDAAKFGAMA
LVGAPVLAGK AIVDALKSEG KPSDENISAT TTKTTTVTTI SSTTTKPVDS TTISEYSSEG
GPQRLTPPKT LALGDAISQN LISPDECKVV VDGEEQDQSV SELLKEEQLS PLDEVQVLDD
KLVVLQPMTY VIDAGDELTP EHLSELNIYD PENQYFIDPS TGMKISFQTL VFDMNVFNPE
TILVKNFSTG KYETLTDALE RPLLDRHTGH MVDPKTGKKI PFFECVNRNW IIRANPEKEK
PAAIENVIDP ATGKVILGDG RICSIVDAIN NGLLDIQSIS VRDPVSGEVI PLRMAIELGV
VDMQAGTVID IQTLKEIPME DAFKLGFLVP GARKPISLEA AVRKGLYDPD TGKLYDSESD
NQVDVQKSIE IGLVDPKISL IVDSKSQKAI KLDCAIEDEL VVAETGQVKD TKTNTLVPFN
VGVEKKLVKT DSITWSLPEV LQREYYSPKT GKILNPTTGE EILLQQAIEL GFVEIDSCLV
KDDDKNSIVS GKQAAKEGLL DTVRGCLNSP NIKLDEAFVK GYLISTKKPL SLVDCLLRGL
YDPETSKFTI DDKTVDLKTA ITLKLINADE LVLLDPKTES IISLTEAIAK GYIDPVNGYV
INPYTGTKLS LNEALENRVL IPPKRKRSLP DAVYRGLYDP KTGEFSNTVT REKLSTERAI
RRGILDPDST IVSVAGEVIP FEKAAQVGIV DSQRGTVRDD NDKEIDFKEA FDRGVLLEAK
KPLRLIEAVI KNVYDESDGT FMDPKSGLKL SFAQAVDNHL LDEDSVQIRD FNTGLYKQLN
LAHASESGVI DGKNAKLVYN NQKITIKHAF DVGILMDTQA PLSLQRALHQ GLFDEKTGKL
TDAKTGRKIT LLESIRSFVI NPQLPCYFDE INEQMHNLHE TCRMGIINRR EGVFREPGSN
TFISLNEALN LGLIVDIENA SFGLYELLAM RFYDMDTRKV IHPVTGRKFN LNEACVEDVV
SLSSSLVKNH KTGKYIRLAQ AIKENIIDDT NGCYNLSPTE QIDLQEARAR GLIVSNRRLM
SLELVMRMHL FRPETGKFCD PTTGEFYDLA EAIQNGFIDP ATTAFKNHVT GKELPLNEAI
ANGDIDVTKG RVFDPKTKSA YNYEVALGRG ILVTVAKPLT ERSEVINRQD SVELLGQTPM
SIVVSKPREM SLEEAIKYNI IDPKTALVRD FDTFKFVPFE VAQNNGIIDL SKRTIVDPKA
LYFVFDPTLV IYVREPVTFE HAAEIKSLNL ETGMLTYHEP NAAAPQQTST ADDSTQPPEP
VVYTLKDATT LGIIDPDSAL VKDLAKSKLV RLPEAFRKGL MDANKANVLN TKTSKLCTLN
EAYESGLIVT PRRSFGLLEG ISFNLYNPTN GCFVDPFQMN PDIIKRKKFT LAEAIASGLI
DPTSTVVRNP STGEILPLTA AIQSGLIDAH EGRIYDEVDS KNNVDLVKAA EKGLLLAAEQ
RQAVFEKFNM CEENVNELLK WVYSIEHKIA TVGGPKEKID ELRNQINALK QIKDEIESQQ
RPVATCLEQI RQIVLTGGDV LSAPEVTTLE NAGRELRSRV DRVNDRTVRL LRRLEVGRDE
LTKLRSELDV FSDWLQSARR TLEDKERALS DLTRLSSQSE SVREFVSDVI GHQADLRFIT
MAAQKFVDES KEFLAILNEF RTSLPERLPH VEPLASAESP IRQEVSLVSA QYKDLMNRVN
ALQDRISGLG GRQREYQDAL DKANEWLRST QPRVSRLIAE PIAGDPKSVQ EQMNEAKALH
NELLSNGRLV DNAQQALDSL LYSLGGQLSP MEINQLEVPI SDLKDKYQKL LDTLGEHCKT
LDKTLVQSQG VQEALDNLGS WVNQAEDKFK LQLRPASLIK ERLQEQIREH KSLLADMQSH
QASIDSVESS AKHLMSTASN ARIAKKVETN LNDVITKFDK LFDKVVKRGE FLDDVSNRLG
KYLDEISGIE QDIVTLQDAL DSRDTNLLSA EELARRMQEL SRHKESLTPS YEDCIRNGKD
LISIRDVTDT STLRDRIKAL ESQWRNINIS LDEKAKLSKQ KAEHQVAYES LKDQVLSWLA
STETRISGLA PVAIDLDKIR QQNDELKPIY KDYRDYASTI DKINDIGSQY DALIRPESPG
RKRSTFSPIK RVSPLRRMSG DARSPSPTKG GILSPLSTGS SGFGSRRSSQ DGFQISELSP
VQQQLSEINN RYSLIGVRIN DRQNELDNMS EEVRKQFENL KNLATFLERI QRQLPKESVS
NKDDADRCIK QARKILEDMY EKQSLLDTTK TQIKDILRRK SDVPGAEQLR VENDNIVEKW
KQLSDICKSR INFSEKLRDF LDTHNNLKNW LDSKERMFTV LGPISSDPRM VQSQVQQVQV
LREEFRTQQP QLKHFQEIGH DVLEHLDADT PDASAVDKKL QDINKRWEDL VSRLDERANS
LGGAADSSKE FDAAVNRLRE ALQQISDNLD SLPSDGDHQE NLRKIENLER QLEGQRPLLA
DAEQSAAALC NILGDPASRA DVNSRVAALE KQYQALQKKL DTKKAETEAT LRDGRHFAEN
CSKTLGWLSG ELSNLAERLL VSAHKPTLQH QIDTHEPIYR EVMAREHEII MLINKGKDLS
DRQQDRTVKR DLERIQQQWE KLRREAVDRH TRLQTCMEHC KKYATTSEVF LAWLRTAEDK
LTDLTPGVLS KSKLDTRLKD LQTFRSEVWK HSGEFENTKG LGETFLTSCD VDKEPIKGEL
QDIRERWERL NNDLIARAHE IENCSRRLGD FNDELRNLDH AVGRCEDRLA AHDALGGAAK
DPKLLDRVKA IREELTNLQK PLQSLKGMAK DICAEARAAG GDADHLTDDV DGISDRIGEL
QSRLDDRLGE LQSAATAVSQ FNEQIKNLGI DLNEIENEIE KLTPPAREIK RVQGQIDDTF
KLQAKLERLV ERIEDGERAA DALVDAGFSP DTAQTRDQIS TLRKTLVRLD NRVRDHSQNL
EDTLRLLQEF YDMESHTMDD IQDITEEFRR MKPVGSELEQ IRRQQEDFCN FRENKIEPLA
QNVEKVNVAG RDLVRSAASG VSTTQIEKDL EKLNDRWNDL KERMNERDRR LDVALLQSGK
FQEALAGLSK WLSDTEEMVA NQKAPSSDYK VVKAQLQEQK FLKRMLLDRQ NSMSSLSSLG
KEVANHCEPS ERTAIEKQLH DLMKRFDALT DGAEKREQDL EEAMEVAKRF HDKITPLELW
LDNTERAVKG MELIPTDEEK IQQRIREHGR LHDEILGKKP DFSDLTDVAS QLMHLVSDEE
AVNLSEKVST ITDRYTGLVD ASDNIGALLA DSRQGLRHLV LTYQELVAWM ERMENELKRF
RSVPVYAEKL LEQMDVLVEL NENIANHAPN VESTVESGAE LMKHISNDEA IQLKDKLDSL
QRRYGELTNR GGDLLKSAQN ALPLVKQFHE AHNRLIEWMQ VAEAALSTSE PRQSDVLRLE
AELVEMRPTL DTVNLVGPKL CQLSPGEGAS TIETIVTRDN RRFDAIVEQI QRKAERLHLS
NQRAKEVTND IDELLEWFRE MDTNLREADP PAIEPKLVRA QLQEHRSVND DISSQKGRVR
DVTAASKKVL RESPQSENTT TLREKLDDLK EIVDTVAQLC SERLGVLEQA LPLSEHFADS
HAGLTTWLDD MEQQISRLSM PALRPDQITQ QQDKNERLLQ SIVEHKPLLD KLNKTGEALG
ALVAEDDSAR INEILDSDNA RYAALRLELR ERQQALDNAL QESSQFSDKL EGMLRALANT
VDQVNQLDPL SALPQKIREQ IDDNDAIMED LDKRTDAFSA VQRAASDVIA KAGNKSDPAV
RDIKSKLEKL NNLWNDVQKA TKKRGSSLDD ILNVAEPFWN QLQSVMKTLK DLEETLSSQE
PPAAQPQEIQ KQQVALQEIR HEIDQTKPEV EQVRRHGSNL MNLCGEPDKP EVKKHIEDLD
HAWDNITALY AKREENLIDA MEKAMEFHET LQNLLKFLTK AEDKFVHLGP VGSDIDAVKK
QIEQLKSFKD EVDPHMVEVE ALNRQAVELT ERTSPEQAAS IREPLTIVNR RWESLLRGMV
ERQKQLEHAL LHLGQFQHAL NELLVWINKT DGTLDQLKPI PGDPQLLEVE LAKLKVLAND
IQAHQNSVDT LNDAGRQLIE SEKGSVEAST TQEKLRKLNQ EWKMLLQKAA DRQHDLEESL
RDAQSYIAEV QDILGWLGDV DAIIGASKPV GGLPETATEQ LERFMEVYNE LEENRVKVET
IQAQGQEYIK RQNQMKVSSN NLTHTLRTLK QRWDAVVSRA SDKKIKLEIA LKEATEFHDT
LQAFVEWLNQ AEKQLANAQP VSRVLETIQA QMEEHKILQK DVSTHREAML LLDKKGTHLK
YFSQKQDVIL IKNLLVSVQH RWERIVSKAA ERTRALDHGY KEAREFNDAW NNMMQYLQET
ETVLDQIIEE ATSSKDPQKI KKCIARLKDT HRQLTGKQSL YDSIMRNGKN LMERAPKSDE
AVIGKMLCEL KDQWTRVLSK SIERQRKLEE ALLLSGQFSD ALGELLEWLK KAKQRLNEDG
PVHGDLETVQ GLCDHHKHIE QDLQKRATQM QGVLKTGRDL ERSGNNPDVG RQLDELQTVW
DEVKSATAKR GERLQYALKD AEQLNGSIQA LFDWLDHAEH KLRYAKNAPD DEKISREMMD
MHIEFMKDLH IRETQKHETF EFAETIIGKA YPDAIPIIKN WLSIIEERWE EVKQWAINRE
AKLEQHLQSL KDLDETIEEL LAWLSGLEAT LLNLERESLP DEIPPLEKLI EDHKEFMENT
ARRQTEVDRA CKPKQLPPGA RKMSRTGKTP VRGSSHDIRE QSPDGTLRRQ SFKGSRDQGL
NNRKSSSRMT PNRDTPDRDR LPHYGPRFSP SSVGPELEFR STRAKLLWDK WRHVWMLSWE
RQRRLNDHLM YLKDLERVRN FSWDDWRKRF LKHMNHKKSR LTDLFRKMDK DNNGLVPRGE
FIDGILNTKF DTSRMEMGAV ADLFDRNGEG LIDWQEFIAA LRPDWQERKP QTDSDKIHDE
VKRLVMLCTC RQKFRVFQVG EGKYRFGDSQ KLRLVRILRS TVMVRVGGGW VALDEFLTKN
DPCRAKGRTN IELREQFILA DGVSQSMASF TPKRPPTNAA QNGNNSNTPP YMSSQGPIIK
VRERSGRSMP MKPTTRSSHS ASTPDSLSDN EGSHGNVSGR YTPRKVTYTS TRTGLTPGGS
RAGSKPNSRP LSRQGSKPPS RHGSTLSLDS TDEHTPSRIP QRKQSGASTV SGTGTTPRPS
RLSVTSTTTR TNGTTTITRK TASGSASPAP TRRNVSGTST PSGMQTPRKS SAEPTFSSTM
RSRTSRGTTP VEKREPFRL
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