ID A0A1I8PMJ6_STOCA Unreviewed; 8806 AA.
AC A0A1I8PMJ6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Microtubule-actin cross-linking factor 1 {ECO:0008006|Google:ProtNLM};
GN Name=106087979 {ECO:0000313|EnsemblMetazoa:SCAU009413-PT};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU009413-PT, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU009413-PT}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU009413-PT};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR RefSeq; XP_013108684.1; XM_013253230.1.
DR EnsemblMetazoa; SCAU009413-RT; SCAU009413-PT; SCAU009413.
DR VEuPathDB; VectorBase:SCAU009413; -.
DR OrthoDB; 5489926at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd21188; CH_PLEC-like_rpt1; 1.
DR CDD; cd21189; CH_PLEC-like_rpt2; 1.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 17.
DR Gene3D; 1.20.58.60; -; 32.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR Gene3D; 3.90.1290.10; Plakin repeat; 12.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR041615; Desmoplakin_SH3.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR049538; PCN-like_spectrin-like_rpt.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR035915; Plakin_repeat_sf.
DR InterPro; IPR001101; Plectin_repeat.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF17902; SH3_10; 1.
DR Pfam; PF00435; Spectrin; 16.
DR Pfam; PF21020; Spectrin_4; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00250; PLEC; 30.
DR SMART; SM00150; SPEC; 36.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF75399; Plakin repeat; 16.
DR SUPFAM; SSF46966; Spectrin repeat; 32.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 130..260
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 272..377
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 923..981
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 8339..8374
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8375..8410
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 8415..8487
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 1..90
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2908..2982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3017..3092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3114..3165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3199..3403
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3480..3504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5533..5592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 6965..7000
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8184..8278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 8545..8806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 498..572
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1063..1090
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 5918..5945
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6325..6378
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6462..6489
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 6782..6809
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2926..2952
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3031..3051
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3052..3081
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3131..3155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3207..3258
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3299..3318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3328..3377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3480..3503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5569..5592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 6965..6986
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8215..8229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8230..8252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8253..8267
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8557..8713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8726..8793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 8806 AA; 992977 MW; 628231C2E19BF79A CRC64;
MTSHSYYKNR LGFDPNEAQY ESSTTTTRRS GSRSSSSHNQ NVNSHHLHAS QHYEHSHTQH
RSQHASPTHH SSASPARISI SPGGASLDHY ADISPAKKAK HSPASASSSI QQPLGGYEDA
LTQFKDERDA IQKKTFTKWV NKHLKKHWKY AKTYTMLHVC VYTNGVPCCP LSAANRRVED
LFEDLRDGHN LLSLLEVLSG EHLPREKGKM RFHMLQNAQM ALDFLRYKKI KLVNIRAEDI
VDGNPKLTLG LIWTIILHFQ ISDIVVGKED NVSAREALLR WARRSTARYP GVRVNDFTSS
WRDGLAFSAL VHRNRPDLLD WRKARNDRPR ERLENAFHIV EKEYGVTRLL DPEDVDTNEP
DEKSLITYIS SLYDVFPEPP SIHPLYDMES QRRVHEYRDL AKQFISWCRE KTAYLQDRSF
PPNLIELKRL LGDLHSFGSD EVSARKREKS KLVQIYKELE RYFEIVGEID VEAELRPEAI
EKAWYRMQTA LQDRDMILQQ EIERLERLQR LADKVQREIK HVDMKITDLE TRITEEARHI
ETLHPVNAKN IVESLETEIR HLEEPIQEMN QDCHILNEGR YTHAAELHKK VNKLHQRWAQ
LRTTFHTVLV QKLSGLKYPV HEKTTTRQQR VVVESRQIET NPYFRDLQEH IEWCQNKLKQ
LLAADYGSDL PSVKKELDRQ QHEHKDIDQF HSKILKDEHQ QTKFSGDELT LYQQRLNQLQ
KVYAELLSTS TKRLSDLDTL QHFLAQASAE LQWLNEKEQI EITRDWADKN LDLSSVHRYY
ENLMSELEKR ELHFGTILDR GETLLNQHHP ASKCIEAHLT ALQQQWAWLL QLTLCLEVHL
KHATEYHQFF AEIKDAEQWL SKRDEILNSE YSKSEFGLDQ GETLLRGMQD LREELNAFGD
TVATLQLRAQ TIVPLNKRRQ PVNRQSPVQA ICAYNQQGQI PVEKGETCTL MDNSGRVKWR
VRTTKGQEGL VPSACLLMPP PDKEAIDAAE RLKRLFDRSV SLWQKKHLRL RQNMIFATIR
VVKDWDFEQF LAMGPEQRTA IRRALNDDAD KLLSEGDPND PQLRRLKREM DEVNRLFDEF
EKRARAEEES KQASRIFTEE CITIKGKLED MARELEQIIS APLPRDLDSL EHVLEIHSDY
ERRLQLLEPE LQHLQETFRT IALKTPALKK SLDNLMILWK ELNTLSNLHK DRLKLLEASL
AGLEDNEHFI SEIENQLAKH QDLPSTPERL EMVFKQLTHM QDLITQQQPQ MDKMTDAADQ
LGRMGVPTKV LGDLKRLHAN VERLNTRWSS ICNQLAERMR SCENAIGLMK NLQSSVQVEE
SWVDGTTERL SAMPTATSAY ELDQYAESLQ KPLKTFRVDF SNANNVPTGE GYVARDADLF
TTTYSTTQFS TTKTTKSVYD ATDYVHTTTT TNGTAGPVPA TTSKQSQIQF NEIHSLKRVQ
TKNENVGTTT TTEFVGGTNV KHLLDMTGIR DPRTGRVLTI GDAIQMRLLD VRTGEMLVGD
KRISLEEAVK QGLIDAKLAH QLLQPGAARD GRDGRELSLL EVIQREITEA ETGYETAEKR
IKVTVDESPD AENPKNIADA ISAGNVDTKT GLYRVKSGKT ITLAEAYERG YLIRHESVTI
KSNALCLSDA IAHGLVDTAG WIADRNSGDK FRLDSAIANQ LIDPNIREVV DAKRDIKITL
TEALNSGILN PKTGRYWNEV TKEKLTFIEA KNRQLIVKPY TLKDICDLNL LDKQSMITSP
MRREKLSIMQ AIESGVLDGN NLKCITKRKG ELVTLQEAIA DGIVLPAESR YRDYMTSEVL
SIPEAVERGL ISSVSQKSIF DIDGFKDMRS NDFVSFNVAL SRGILRRKSN GFALETSRDT
QVPLEVALNE GLIRPEVYEM FNKGIGVHNA SGKELSVFDL CYHSLIDPKT GYLLDPKAEE
TVPLDLAIER KFITPEGALL LSSLLNITLT TETVTRTINR YVTIRASSQE PLETTIVLTF
TEALRQGFID EERQLFKDPK TGNIYSVQQA LSYGLLQPDA NETVPEPTNR KKTKSTITIV
TKQIVPESEP IKLNTQNFIE KSVEIPIAEE VRKPGKISTD FIQSEKTSYV QQNVRERQII
EFPPGGWPLK DAIEQQLFNP DTGVFHIKNT ERAVTFEECI NKYIINSLSV SVIDPRTGEK
LSIRNAFERD IIDSYGSYTN TNDDVETMRS AIGQGKIILE HVPSTKTSAR EQCILRVSKI
NNLPEIVEIS TPLLSGSSQK FVEVRTVQRE LTSPEPLQIA PGAIYDPSTA LVIFTHNGQT
ENIFDAARHG LIDESLIRIV DPQTKEVISI SEALARNIYD PQNGTILTDD TYAVDILTAI
QKGLIVVAGA PLVAAEGALR TIRFVTDPRT GEQIPVEVAY ERGIVSRDQL RKTKSVESDA
SEDKVVVLQK MRKMILKPDD AFKKGIIDVV ARDILENKDN FLGDNNEVLN ITEALQRGQI
DGSKGKIADP QRNRFLNISE AVKERVIDPE ETNHILIPLA QSLSIPKLME QGLVDTKTQT
IVHPESGYGL NIREAIVCDV LDQYSKLKRP IKCTLEEAIE KHIVDPDEST FNVNGKVLTL
AQAVNADIFE KTSDKVKPLV PIPPVGMTFP VVVEKGLLKP ENVSVIHPES RKEIPLKKAI
EEGFIMSIPY PPQADAMEVH HAVQQGLINI VDQTFRHPKD NGQATPLRPA LETGRLVVKP
ISDFVVTQQP VARTEIMETI TAVHTVTTKT IELVQGYVLI SNNEVQNIKT GEVWTIEEAK
AKGILKEEET SKESRSVTGN KDNIEELLQQ PNTEDQTTIS ERVIQNTTKN KNLIVTQQGT
IQMEGHPMPT PGQPMPGQET PKQDSKLSAT LNNVKEAAKM GALGIVAAPV LAGGALVSGI
KQLVKTSTTT TTTTEFNDET QKVISTSATL GAVETNDKFP RETAPSPHNP NGSHASSSMT
TTITSTVPQQ PGITKDAPKP PTQDSAQSDD VLPHLKDSKT KATDVHTIDN LMKDTENFIN
TTTANFINQE KNVEGQHLPK TGVHSPADAT RSLEGNDNLQ VKPSDQITSA LSHEEPNKKS
KDRTPSDKDR TVDKDRPLQE ASDNATNKGV SSNVIITTEM SATTTDPINE IVEVSETTGQ
PKDRKPSSGD LESSKGNQTT TTTTTTITTS KITKGEGFEP SEGVPSLTEA SLKGIVDDKH
PQKYGVVTDF IKHETNVLHR PEESLASPSG LKSQLVDGSL QSDKPESDKP QLIGQTTRTT
TTTTITTTTE QVGQFNAPLQ PFSEDVETDL ESFGGDKSQQ DSPNNKQGEK PKDGSLPANL
LKSGQTPPSS ILTEETTQKH PSTMDKSEND ESQQFNNAST APQVASGEKS PVSATDVSTI
VKSTHGEDPQ TFTPLDTKDK PSLAARKSTD KLGDLTQPQN ATDDPHRRVV DFIQAEKGDH
TAGNVLQNVK DAAKFGAMAL VGAPVLAGKA IVDALKSEGK PSDENISATT TKTTTVTTIS
STTTKPVDST TISEYSSEGG PQRLTPPKTL ALGDAISQNL ISPDECKVVV DGEEQDQSVS
ELLKEEQLSP LDEVQVLDDK LVVLQPMTYV IDAGDELTPE HLSELNIYDP ENQYFIDPST
GMKISFQTLV FDMNVFNPET ILVKNFSTGK YETLTDALER PLLDRHTGHM VDPKTGKKIP
FFECVNRNWI IRANPEKEKP AAIENVIDPA TGKVILGDGR ICSIVDAINN GLLDIQSISV
RDPVSGEVIP LRMAIELGVV DMQAGTVIDI QTLKEIPMED AFKLGFLVPG ARKPISLEAA
VRKGLYDPDT GKLYDSESDN QVDVQKSIEI GLVDPKISLI VDSKSQKAIK LDCAIEDELV
VAETGQVKDT KTNTLVPFNV GVEKKLVKTD SITWSLPEVL QREYYSPKTG KILNPTTGEE
ILLQQAIELG FVEIDSCLVK DDDKNSIVSG KQAAKEGLLD TVRGCLNSPN IKLDEAFVKG
YLISTKKPLS LVDCLLRGLY DPETSKFTID DKTVDLKTAI TLKLINADEL VLLDPKTESI
ISLTEAIAKG YIDPVNGYVI NPYTGTKLSL NEALENRVLI PPKRKRSLPD AVYRGLYDPK
TGEFSNTVTR EKLSTERAIR RGILDPDSTI VSVAGEVIPF EKAAQVGIVD SQRGTVRDDN
DKEIDFKEAF DRGVLLEAKK PLRLIEAVIK NVYDESDGTF MDPKSGLKLS FAQAVDNHLL
DEDSVQIRDF NTGLYKQLNL AHASESGVID GKNAKLVYNN QKITIKHAFD VGILMDTQAP
LSLQRALHQG LFDEKTGKLT DAKTGRKITL LESIRSFVIN PQLPCYFDEI NEQMHNLHET
CRMGIINRRE GVFREPGSNT FISLNEALNL GLIVDIENAS FGLYELLAMR FYDMDTRKVI
HPVTGRKFNL NEACVEDVVS LSSSLVKNHK TGKYIRLAQA IKENIIDDTN GCYNLSPTEQ
IDLQEARARG LIVSNRRLMS LELVMRMHLF RPETGKFCDP TTGEFYDLAE AIQNGFIDPA
TTAFKNHVTG KELPLNEAIA NGDIDVTKGR VFDPKTKSAY NYEVALGRGI LVTVAKPLTE
RSEVINRQDS VELLGQTPMS IVVSKPREMS LEEAIKYNII DPKTALVRDF DTFKFVPFEV
AQNNGIIDLS KRTIVDPKAL YFVFDPTLVI YVREPVTFEH AAEIKSLNLE TGMLTYHEPN
AAAPQQTSTA DDSTQPPEPV VYTLKDATTL GIIDPDSALV KDLAKSKLVR LPEAFRKGLM
DANKANVLNT KTSKLCTLNE AYESGLIVTP RRSFGLLEGI SFNLYNPTNG CFVDPFQMNP
DIIKRKKFTL AEAIASGLID PTSTVVRNPS TGEILPLTAA IQSGLIDAHE GRIYDEVDSK
NNVDLVKAAE KGLLLAAEQR QAVFEKFNMC EENVNELLKW VYSIEHKIAT VGGPKEKIDE
LRNQINALKQ IKDEIESQQR PVATCLEQIR QIVLTGGDVL SAPEVTTLEN AGRELRSRVD
RVNDRTVRLL RRLEVGRDEL TKLRSELDVF SDWLQSARRT LEDKERALSD LTRLSSQSES
VREFVSDVIG HQADLRFITM AAQKFVDESK EFLAILNEFR TSLPERLPHV EPLASAESPI
RQEVSLVSAQ YKDLMNRVNA LQDRISGLGG RQREYQDALD KANEWLRSTQ PRVSRLIAEP
IAGDPKSVQE QMNEAKALHN ELLSNGRLVD NAQQALDSLL YSLGGQLSPM EINQLEVPIS
DLKDKYQKLL DTLGEHCKTL DKTLVQSQGV QEALDNLGSW VNQAEDKFKL QLRPASLIKE
RLQEQIREHK SLLADMQSHQ ASIDSVESSA KHLMSTASNA RIAKKVETNL NDVITKFDKL
FDKVVKRGEF LDDVSNRLGK YLDEISGIEQ DIVTLQDALD SRDTNLLSAE ELARRMQELS
RHKESLTPSY EDCIRNGKDL ISIRDVTDTS TLRDRIKALE SQWRNINISL DEKAKLSKQK
AEHQVAYESL KDQVLSWLAS TETRISGLAP VAIDLDKIRQ QNDELKPIYK DYRDYASTID
KINDIGSQYD ALIRPESPGR KRSTFSPIKR VSPLRRMSGD ARSPSPTKGG ILSPLSTGSS
GFGSRRSSQD GFQISELSPV QQQLSEINNR YSLIGVRIND RQNELDNMSE EVRKQFENLK
NLATFLERIQ RQLPKESVSN KDDADRCIKQ ARKILEDMYE KQSLLDTTKT QIKDILRRKS
DVPGAEQLRV ENDNIVEKWK QLSDICKSRI NFSEKLRDFL DTHNNLKNWL DSKERMFTVL
GPISSDPRMV QSQVQQVQVL REEFRTQQPQ LKHFQEIGHD VLEHLDADTP DASAVDKKLQ
DINKRWEDLV SRLDERANSL GGAADSSKEF DAAVNRLREA LQQISDNLDS LPSDGDHQEN
LRKIENLERQ LEGQRPLLAD AEQSAAALCN ILGDPASRAD VNSRVAALEK QYQALQKKLD
TKKAETEATL RDGRHFAENC SKTLGWLSGE LSNLAERLLV SAHKPTLQHQ IDTHEPIYRE
VMAREHEIIM LINKGKDLSD RQQDRTVKRD LERIQQQWEK LRREAVDRHT RLQTCMEHCK
KYATTSEVFL AWLRTAEDKL TDLTPGVLSK SKLDTRLKDL QTFRSEVWKH SGEFENTKGL
GETFLTSCDV DKEPIKGELQ DIRERWERLN NDLIARAHEI ENCSRRLGDF NDELRNLDHA
VGRCEDRLAA HDALGGAAKD PKLLDRVKAI REELTNLQKP LQSLKGMAKD ICAEARAAGG
DADHLTDDVD GISDRIGELQ SRLDDRLGEL QSAATAVSQF NEQIKNLGID LNEIENEIEK
LTPPAREIKR VQGQIDDTFK LQAKLERLVE RIEDGERAAD ALVDAGFSPD TAQTRDQIST
LRKTLVRLDN RVRDHSQNLE DTLRLLQEFY DMESHTMDDI QDITEEFRRM KPVGSELEQI
RRQQEDFCNF RENKIEPLAQ NVEKVNVAGR DLVRSAASGV STTQIEKDLE KLNDRWNDLK
ERMNERDRRL DVALLQSGKF QEALAGLSKW LSDTEEMVAN QKAPSSDYKV VKAQLQEQKF
LKRMLLDRQN SMSSLSSLGK EVANHCEPSE RTAIEKQLHD LMKRFDALTD GAEKREQDLE
EAMEVAKRFH DKITPLELWL DNTERAVKGM ELIPTDEEKI QQRIREHGRL HDEILGKKPD
FSDLTDVASQ LMHLVSDEEA VNLSEKVSTI TDRYTGLVDA SDNIGALLAD SRQGLRHLVL
TYQELVAWME RMENELKRFR SVPVYAEKLL EQMDVLVELN ENIANHAPNV ESTVESGAEL
MKHISNDEAI QLKDKLDSLQ RRYGELTNRG GDLLKSAQNA LPLVKQFHEA HNRLIEWMQV
AEAALSTSEP RQSDVLRLEA ELVEMRPTLD TVNLVGPKLC QLSPGEGAST IETIVTRDNR
RFDAIVEQIQ RKAERLHLSN QRAKEVTNDI DELLEWFREM DTNLREADPP AIEPKLVRAQ
LQEHRSVNDD ISSQKGRVRD VTAASKKVLR ESPQSENTTT LREKLDDLKE IVDTVAQLCS
ERLGVLEQAL PLSEHFADSH AGLTTWLDDM EQQISRLSMP ALRPDQITQQ QDKNERLLQS
IVEHKPLLDK LNKTGEALGA LVAEDDSARI NEILDSDNAR YAALRLELRE RQQALDNALQ
ESSQFSDKLE GMLRALANTV DQVNQLDPLS ALPQKIREQI DDNDAIMEDL DKRTDAFSAV
QRAASDVIAK AGNKSDPAVR DIKSKLEKLN NLWNDVQKAT KKRGSSLDDI LNVAEPFWNQ
LQSVMKTLKD LEETLSSQEP PAAQPQEIQK QQVALQEIRH EIDQTKPEVE QVRRHGSNLM
NLCGEPDKPE VKKHIEDLDH AWDNITALYA KREENLIDAM EKAMEFHETL QNLLKFLTKA
EDKFVHLGPV GSDIDAVKKQ IEQLKSFKDE VDPHMVEVEA LNRGLERQAV ELTERTSPEQ
AASIREPLTI VNRRWESLLR GMVERQKQLE HALLHLGQFQ HALNELLVWI NKTDGTLDQL
KPIPGDPQLL EVELAKLKVL ANDIQAHQNS VDTLNDAGRQ LIESEKGSVE ASTTQEKLRK
LNQEWKMLLQ KAADRQHDLE ESLRDAQSYI AEVQDILGWL GDVDAIIGAS KPVGGLPETA
TEQLERFMEV YNELEENRVK VETIQAQGQE YIKRQNQMKV SSNNLTHTLR TLKQRWDAVV
SRASDKKIKL EIALKEATEF HDTLQAFVEW LNQAEKQLAN AQPVSRVLET IQAQMEEHKI
LQKDVSTHRE AMLLLDKKGT HLKYFSQKQD VILIKNLLVS VQHRWERIVS KAAERTRALD
HGYKEAREFN DAWNNMMQYL QETETVLDQI IEEATSSKDP QKIKKCIARL KDTHRQLTGK
QSLYDSIMRN GKNLMERAPK SDEAVIGKML CELKDQWTRV LSKSIERQRK LEEALLLSGQ
FSDALGELLE WLKKAKQRLN EDGPVHGDLE TVQGLCDHHK HIEQDLQKRA TQMQGVLKTG
RDLERSGNNP DVGRQLDELQ TVWDEVKSAT AKRGERLQYA LKDAEQLNGS IQALFDWLDH
AEHKLRYAKN APDDEKISRE MMDMHIEFMK DLHIRETQKH ETFEFAETII GKAYPDAIPI
IKNWLSIIEE RWEEVKQWAI NREAKLEQHL QSLKDLDETI EELLAWLSGL EATLLNLERE
SLPDEIPPLE KLIEDHKEFM ENTARRQTEV DRACKPKQLP PGARKMSRTG KTPVRGSSHD
IREQSPDGTL RRQSFKGSRD QGLNNRKSSS RMTPNRDTPD RDRLPHYGPR FSPSSVGPEL
EFRSTRAKLL WDKWRHVWML SWERQRRLND HLMYLKDLER VRNFSWDDWR KRFLKHMNHK
KSRLTDLFRK MDKDNNGLVP RGEFIDGILN TKFDTSRMEM GAVADLFDRN GEGLIDWQEF
IAALRPDWQE RKPQTDSDKI HDEVKRLVML CTCRQKFRVF QVGEGKYRFG DSQKLRLVRI
LRSTVMVRVG GGWVALDEFL TKNDPCRADE HLAELMPIFE RIRAQEQVPC AFPIHMGAGG
TVFVRCNSSR SVPLSPHVMH CHPTTHWVRE RSGRSMPMKP TTRSSHSAST PDSLSDNEGS
HGNVSGRYTP RKVTYTSTRT GLTPGGSRAG SKPNSRPLSR QGSKPPSRHG STLSLDSTDE
HTPSRIPQRK QSGASTVSGT GTTPRPSRLS VTSTTTRTNG TTTITRKTAS GSASPAPTRN
GGMSRSSSIP ALTGFGYKPS YRPSRIPVKV SNSFDKSLSA NSSPTNSTSN SLNPNSSLGR
NVSGTSTPSG MQTPRKSSAE PTFSSTMRSR TSRGTTPVEK REPFRL
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