ID A0A1I8PNV1_STOCA Unreviewed; 511 AA.
AC A0A1I8PNV1;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Equilibrative nucleoside transporter 1 {ECO:0008006|Google:ProtNLM};
GN Name=106083846 {ECO:0000313|EnsemblMetazoa:SCAU009787-PB};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU009787-PB, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU009787-PB}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU009787-PB};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
CC {ECO:0000256|ARBA:ARBA00007965}.
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DR RefSeq; XP_013102560.1; XM_013247106.1.
DR AlphaFoldDB; A0A1I8PNV1; -.
DR EnsemblMetazoa; SCAU009787-RB; SCAU009787-PB; SCAU009787.
DR GeneID; 106083846; -.
DR KEGG; scac:106083846; -.
DR VEuPathDB; VectorBase:SCAU009787; -.
DR OrthoDB; 517168at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002259; Eqnu_transpt.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR10332; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER; 1.
DR PANTHER; PTHR10332:SF10; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A; 1.
DR Pfam; PF01733; Nucleoside_tran; 1.
DR PIRSF; PIRSF016379; ENT; 2.
DR PRINTS; PR01130; DERENTRNSPRT.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..179
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 191..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 232..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 394..412
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 432..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..508
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 511 AA; 57820 MW; 17AC14B4CF0CD68F CRC64;
MLRYDTMDDD QRGLVHNEQP TAVNDDDDDD YAGGFVAGGG GGPHDVEILP AGENDFHNVE
LHSHIQISDA PPDKWNYTYL VFYFLGTATM TPWNFFITAE DYWMYKFRNT TLNESTHAEE
ELTPMQKSFS CDLTLTASIS GTTFLILHAI YGQKISLRLR MQGTLVLILV IFMLTAGFVE
TNTDKWQEQF FLITLLTVVI INICSATMSG ALFGIAGLFP SEYMTAVVSG QALGGIFTAL
TFLMVLAFGA APNTTAFIFF SIGIALIFLN IICYAIVERK NFFKYYVEGG DKFKIVYDDP
THSRMVDRGV ALEPNIRDVL SKMYVHAVTI LLLYTTTLSV YPSVTILMQS QDYGKGKAWN
DIYYMPVVNY LFFNSGDYLG RIISGIWGRP RKNVHTVLLM VLLRMIYLPL FLCSNSTQHI
FLPVIVSSDV AFIFMMLTFA ISNGYITNIL LNMVPRYLIF CRKQRIIHLF WFYFRCVMQH
EKEMASSIMA ASLSCGLAIG SMITMLFVQM I
//
