ID A0A1I8PQG9_STOCA Unreviewed; 1299 AA.
AC A0A1I8PQG9;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN Name=106091788 {ECO:0000313|EnsemblMetazoa:SCAU010209-PC};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU010209-PC, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU010209-PC}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU010209-PC};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013113903.1; XM_013258449.1.
DR EnsemblMetazoa; SCAU010209-RC; SCAU010209-PC; SCAU010209.
DR GeneID; 106091788; -.
DR VEuPathDB; VectorBase:SCAU010209; -.
DR OrthoDB; 2905462at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd14954; NHL_TRIM71_like; 1.
DR CDD; cd16524; RING-HC_NHL-1-like; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 3.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR24104; E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED; 1.
DR PANTHER; PTHR24104:SF54; THIN, ISOFORM C; 1.
DR Pfam; PF01436; NHL; 6.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF101898; NHL repeat; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51125; NHL; 6.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 10..52
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REPEAT 1024..1067
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1071..1114
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1121..1161
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1165..1208
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1212..1255
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 1259..1299
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REGION 299..318
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 330..439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 482..905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 917..962
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 975..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 330..367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 403..437
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 482..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 515..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 559..582
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 594..630
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 675..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..740
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 754..793
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 860..903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..961
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1299 AA; 141388 MW; EBC8CACD84D4A16A CRC64;
MEQFEQLLTC CVCLDRYRIP KLLPCQHSFC MEPCMEGLVD YVRRQVKCPE CRAEHRIPYN
GVQAFPTNVT LQRFLELHIE ITGELPDPTS GQIMERCGVC SEKSYLNPCA HCEKKICDDC
KSAHMDILRR EITRFNSQIR RSLHRLQDSL ALIEKNMVCL QTNCASTTEE IDEIYLRITK
AIKDRADQLK QEIDRYLTIE LRNLKTLKEN LDGEISNINS NCDIVDKYMN ETVEWDDCEL
MDTKEIFLKT VEFLRHFEYE NSDYSRRVRF MVSIDPNQLV LNLATFGDLN IAPHSNAGGM
SGSSHLAPPS SLQPGLMRSK SDHRLATQFR QQEERIGYND EPVLGGRKFG ERPVRVNNER
DRYGDSGSSR YGRSGAGGDY DYGENDYDDS SSRTGKSRFR SRFVRSHQND DSDNEEKQQQ
RLEEKKLKDK VRDGEDASRG QLSGIIRLSD CARVIQRLAD IGKEKKEKKV DASAQAAIQA
AIQAQKASMQ RPKQNPPATQ RQVSEDDEIN HIKRQNKNAP SSSTAASAAA TATATETERP
TVDRSKPAAP VPAQVAAVKK TTRSGSSDST ASTESSASSA AAGRAPSAAR FSVSRESPAR
TSRPTAGTSA TTTASTAATT GTTTTEKKPF VSRFLPQHTT APAEKSKVES DSSSEEETST
EESEDEEVDV KKPSASSASK PTSSAATSGY SAGSSTTSSY RDRLDSRRSS RDDTASKNSS
AYATPSSSST ATSSGYGGST SAAARARDTD TDRYGSGASG SSYTSRFLNK SKSSAIVSQP
SLSTPNASFD EDANGTGDDS DSRYGTGRSR YLAMKERRNR LARSRSSHQF GNDDDDVDEP
VSPTTASPSA YLASRYSGYG GTDLSRSRSS HALKSRDSSP VNERTSSRSG AGASTSNADN
KDGEALSSWA RYLKNKYGSK SSKDTPSSSG RDNLGSSSTS TALPSSSHGA SGSSRSHAAS
DVSRRLSLGL PLRQVSELGS SDDDASKNGL GSPTSPMVAA AAHGMAGVAG TSPKQLYLRK
RQQLFQLGGR GSEPGSFTWP RGLAVGPDNS IVVADSSNHR VQVFDSNGIF VKQFGEYGNG
EGEFDCLAGV AVNRIGQYII ADRYNHRIQV LDPQGRFLRA FGSQGTADGK FNYPWGVTTD
ALGFIYVCDK ENHRVQVFQS DGSFVGKFGT CGRGEGQLEH PHYIAVSNTN RVIVSDSNNH
RIQIFDVNGK VLSTFGGEGS DDGQFKFPRG VAVDDQGYIF VADSGNNRIQ IFNPDGSFLK
TFGSWGSGDS EFKGLEGVAI MSNGNILVCD RENHRVQVF
//
