ID A0A1I8PUQ2_STOCA Unreviewed; 525 AA.
AC A0A1I8PUQ2;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 28-JUN-2023, entry version 32.
DE RecName: Full=UDP-glucuronosyltransferase {ECO:0000256|RuleBase:RU362059};
DE EC=2.4.1.17 {ECO:0000256|RuleBase:RU362059};
GN Name=106091792 {ECO:0000313|EnsemblMetazoa:SCAU011291-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU011291-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU011291-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU011291-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|RuleBase:RU362059};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU362059}; Single-
CC pass membrane protein {ECO:0000256|RuleBase:RU362059}.
CC -!- SIMILARITY: Belongs to the UDP-glycosyltransferase family.
CC {ECO:0000256|ARBA:ARBA00009995, ECO:0000256|RuleBase:RU003718}.
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DR RefSeq; XP_013113908.1; XM_013258454.1.
DR AlphaFoldDB; A0A1I8PUQ2; -.
DR EnsemblMetazoa; SCAU011291-RA; SCAU011291-PA; SCAU011291.
DR GeneID; 106091792; -.
DR KEGG; scac:106091792; -.
DR VEuPathDB; VectorBase:SCAU011291; -.
DR OrthoDB; 382054at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR InterPro; IPR035595; UDP_glycos_trans_CS.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF145; EG:EG0003.4 PROTEIN-RELATED; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
DR PROSITE; PS00375; UDPGT; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676,
KW ECO:0000256|RuleBase:RU003718}; Membrane {ECO:0000256|RuleBase:RU362059};
KW Signal {ECO:0000256|RuleBase:RU362059};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003718};
KW Transmembrane {ECO:0000256|RuleBase:RU362059};
KW Transmembrane helix {ECO:0000256|RuleBase:RU362059}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|RuleBase:RU362059"
FT CHAIN 24..525
FT /note="UDP-glucuronosyltransferase"
FT /evidence="ECO:0000256|RuleBase:RU362059"
FT /id="PRO_5009030359"
FT TRANSMEM 481..501
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362059"
SQ SEQUENCE 525 AA; 59434 MW; 74E78CD58BA5A167 CRC64;
MRLEIVLALA LVISTSLVDF GQGAKILSIF PYPGPSQYIY ISALLKALAE RGHEVTSIST
YPQKEKLKNF RDVAVMENIH LFEGFIEEAA SGEKKSYIQE FLELAEPGKL VVTNVLENAE
VKKIMKNEKF DLIISEVLVS EALLGLGEHF KAPIVAVSTF GTINFIDYLV GNTSPLSYIP
HISVPYGNHM SLKERAANLL METVDQLCFN YFVLPLQEEI YRKYFPSAQL SLDQARKNVS
LVLLNDHFTL RFPRPYVPNM IEVGGLHVKA NPDPLTEDLQ EYLDKASEGV IYFSLGSNIQ
SKDLSPKTLK VLLEGFRELK IKVLWKFEAE DLPGKPDNVL IRKWFNQPAI LAHPNVKLFI
SHGGYMSTIE TIFHGTPVLG LPIIADQFMN VKNAVKAGYA LELQLNEMTK DSFKKTIKEL
WSNPKYSEAV GRLSKRYRDQ PMTPLETAIY WVEYVLRNEG APYMRNAGQD LSFMEYHNLD
VFLLLAAGVI LIFVVIFYAI CSLKKMCFKA GKVSKNSKKD KLKKR
//
