ID A0A1I8PXX6_STOCA Unreviewed; 1402 AA.
AC A0A1I8PXX6;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=SAM domain-containing protein {ECO:0000259|Pfam:PF00536};
GN Name=106083606 {ECO:0000313|EnsemblMetazoa:SCAU012117-PA};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU012117-PA, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU012117-PA}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU012117-PA};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR RefSeq; XP_013102195.1; XM_013246741.1.
DR STRING; 35570.A0A1I8PXX6; -.
DR EnsemblMetazoa; SCAU012117-RA; SCAU012117-PA; SCAU012117.
DR GeneID; 106083606; -.
DR KEGG; scac:106083606; -.
DR VEuPathDB; VectorBase:SCAU012117; -.
DR OrthoDB; 2905251at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd20101; MBT_L3MBTL1-like_rpt1; 1.
DR CDD; cd20103; MBT_L3MBTL1-like_rpt3; 1.
DR Gene3D; 2.30.30.140; -; 3.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR004092; Mbt.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR002515; Znf_C2H2C.
DR InterPro; IPR036060; Znf_C2H2C_sf.
DR PANTHER; PTHR12247:SF131; LD05287P; 1.
DR PANTHER; PTHR12247; POLYCOMB GROUP PROTEIN; 1.
DR Pfam; PF02820; MBT; 3.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00561; MBT; 3.
DR SUPFAM; SSF103637; CCHHC domain; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 3.
DR PROSITE; PS51079; MBT; 3.
DR PROSITE; PS51802; ZF_CCHHC; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REPEAT 825..924
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 932..1033
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT REPEAT 1040..1136
FT /note="MBT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00459"
FT DOMAIN 1323..1385
FT /note="SAM"
FT /evidence="ECO:0000259|Pfam:PF00536"
FT REGION 430..610
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 626..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..511
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..531
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 532..546
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 547..565
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1402 AA; 156892 MW; 7D93BAA452BFA07E CRC64;
MNPLNAPQQS QTQYFITTGM PPLVPTSDQH LTTTASTLTQ QSLQLPTVAT NNPSINNQQA
NHFVDANKFV TTNYVPVLIT NQTLLTNIEP IQQHHQQQQQ QSQNISPSII SVTNSPVVAS
AATANIPLMP TNPGGNVTYV MTSPQTPNFA PVLPGQNGTV SVLLTTPTTT TMATSGHVAA
PFLIRSTSTQ VKQQHPQHQL QQSIHNQTFN TQQMNAELLK QVNTGTTLLK TSLLQNKSAP
KMPSNINSGG GGAIAQALVT QAVQKLPQVS LLQNSKNKQT VTVVGGSSSH SFVSGASIIA
GKSSSTTSKS EKIKETSDAA KSSYEIRVGD LNAEVSLIKK ATLNTDTPSA STSKVETNSL
LKPSVDLKRK RDKSLAGVVQ NSKPGDVVVN EKSHSLLKAK NNVAECNTNP VSPRSQRSKS
WNSILKSQTQ ALVSNTNERR HSEPAKMEKP LTDTAAEGQK SAKELGQMEN SNNIILEEFE
DEEYLESSGE KTNGALKQTS EEPTLSQESN NEKECGNKEI NQMEEETTKK STITNDMPNN
INANSDEIEE NNKEQTKKLE SDSDDDVTIL PMDNSLVEPI EIDDDDEECV GPQKVPNDET
SPSTKDKQKC NDSLLCEEQI LVSSSSSISN QSLDQISLTS SVPRKSPKIE PDKAATSTAP
ILKRSLTDRK QTFMKEEPPS NNGYSSVLDM LSNFDMLNWK ERLGTGRGTN MKFQLNEFNL
VQLHEKIPGR TKSYTAYEKP IYERDDLQIR SQTVEPQIYY MCRRCKVRAL ALDFLAPEFC
SMYCLKRDCR KRQREDQASI IRKKHRYLVS NNNPPPLAYI TQPKFRWSNY LKANYTSMAA
PISLFLNPFP TGPNYFKIGM KLEAIDPENC ALFCVCTVVD INGYRLKLSF DGYDSSYDFW
INADSMDIFP PGWCAKTNRI LQPPKGINAS KFNWAWYFNK EKGLSAPRQL FTHLNSSSLS
PRNPFQIGMH LEAEDLNDTG KLCVASVADV LDDRIRIHFD GWDDCYDIIV DINSPYIHPC
GWHEGRHQLV VPPDCENSAF SWKNYIKSQG KGIIASEELF MPREPIHFKP NMKLEVVDPR
NSSLIRPATV VSHKGHRVKL HLDGWPNDYC FWLEDDSPDL HPIGWCDATG HDLEPPPGFQ
MGKQKMPCPT PGCRGIGNAK KSFMAVHANR DCCPYVPENW RLVVEKPPRV GYDDIVRTLP
RLYKINNVPH NSQRLSDHQV SERLQILDNI KTRNVLMHQD KTDTFKESIS MSMGTVKREE
SKETKHNKLE IKRIDEEPSL DVNIDIVKEF LCDYGPRLQQ AYTLWQKNFT LDTAKIKRNP
LLWSVSEVGV FVDLYLNCPP TAALFAQEDI DGEAFLLLQQ CDLTERLNVK LGHAVKLYSC
ILQLRTLAVT KFNVAYRKVP PK
//
