ID A0A1I8PZA7_STOCA Unreviewed; 175 AA.
AC A0A1I8PZA7;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=sulfiredoxin {ECO:0000256|ARBA:ARBA00013055};
DE EC=1.8.98.2 {ECO:0000256|ARBA:ARBA00013055};
GN Name=106084421 {ECO:0000313|EnsemblMetazoa:SCAU012438-PD};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU012438-PD, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU012438-PD}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU012438-PD};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[protein]-dithiol + ATP + S-hydroxy-S-oxy-L-cysteinyl-
CC [peroxiredoxin] = [protein]-disulfide + ADP + phosphate + S-hydroxy-
CC L-cysteinyl-[peroxiredoxin]; Xref=Rhea:RHEA:17545, Rhea:RHEA-
CC COMP:10593, Rhea:RHEA-COMP:10594, Rhea:RHEA-COMP:13681, Rhea:RHEA-
CC COMP:17976, ChEBI:CHEBI:29950, ChEBI:CHEBI:30616, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:50058, ChEBI:CHEBI:61973, ChEBI:CHEBI:61974,
CC ChEBI:CHEBI:456216; EC=1.8.98.2;
CC Evidence={ECO:0000256|ARBA:ARBA00034024};
CC -!- SIMILARITY: Belongs to the sulfiredoxin family.
CC {ECO:0000256|ARBA:ARBA00009609}.
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DR RefSeq; XP_013103550.1; XM_013248096.1.
DR AlphaFoldDB; A0A1I8PZA7; -.
DR EnsemblMetazoa; SCAU012438-RD; SCAU012438-PD; SCAU012438.
DR GeneID; 106084421; -.
DR VEuPathDB; VectorBase:SCAU012438; -.
DR OrthoDB; 5482730at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0032542; F:sulfiredoxin activity; IEA:UniProtKB-EC.
DR CDD; cd16395; Srx; 1.
DR Gene3D; 3.90.1530.10; Conserved hypothetical protein from pyrococcus furiosus pfu- 392566-001, ParB domain; 1.
DR InterPro; IPR003115; ParB/Sulfiredoxin_dom.
DR InterPro; IPR036086; ParB/Sulfiredoxin_sf.
DR InterPro; IPR016692; Sulfiredoxin.
DR PANTHER; PTHR21348:SF2; SULFIREDOXIN-1; 1.
DR PANTHER; PTHR21348; UNCHARACTERIZED; 1.
DR SMART; SM00470; ParB; 1.
DR SUPFAM; SSF110849; ParB/Sulfiredoxin; 1.
PE 3: Inferred from homology;
KW Antioxidant {ECO:0000256|ARBA:ARBA00022862};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 67..161
FT /note="ParB/Sulfiredoxin"
FT /evidence="ECO:0000259|SMART:SM00470"
SQ SEQUENCE 175 AA; 19445 MW; 92501549E81FBB41 CRC64;
MELIAKFVLP ASRRVLFFAK PTTVAVIFLL VGLLGAFNNH STAQMLSTTA TSCVDRSVHS
ANIDEIHNVP MNVIHRPIPP VLDENKVKSI METLESEKTS DNVPPIDVLW IKGSKGGNYF
YSFGGCHRFE AYKRLNRDTI KAKLVNSTLS DLYTYMGSST PKNLVTINSQ INQSK
//
