ID   A0A1I8Q3B6_STOCA        Unreviewed;       830 AA.
AC   A0A1I8Q3B6;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Tropomyosin {ECO:0008006|Google:ProtNLM};
GN   Name=106089563 {ECO:0000313|EnsemblMetazoa:SCAU013479-PV};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU013479-PV, ECO:0000313|Proteomes:UP000095300};
RN   [1] {ECO:0000313|EnsemblMetazoa:SCAU013479-PV}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU013479-PV};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- FUNCTION: Tropomyosin, in association with the troponin complex, plays
CC       a central role in the calcium dependent regulation of muscle
CC       contraction. {ECO:0000256|ARBA:ARBA00002987}.
CC   -!- SIMILARITY: Belongs to the tropomyosin family.
CC       {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
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DR   RefSeq; XP_013110870.1; XM_013255416.1.
DR   AlphaFoldDB; A0A1I8Q3B6; -.
DR   EnsemblMetazoa; SCAU013479-RV; SCAU013479-PV; SCAU013479.
DR   GeneID; 106089563; -.
DR   VEuPathDB; VectorBase:SCAU013479; -.
DR   OrthoDB; 2917119at2759; -.
DR   Proteomes; UP000095300; Unassembled WGS sequence.
DR   Gene3D; 1.20.5.170; -; 2.
DR   InterPro; IPR000533; Tropomyosin.
DR   PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR   PANTHER; PTHR19269:SF45; TROPOMYOSIN-1, ISOFORMS 33_34; 1.
DR   Pfam; PF00261; Tropomyosin; 1.
DR   PRINTS; PR00194; TROPOMYOSIN.
DR   SUPFAM; SSF57997; Tropomyosin; 1.
DR   PROSITE; PS00326; TROPOMYOSIN; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   REGION          31..51
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          107..140
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          402..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          619..821
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        107..124
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        125..140
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        210..234
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..313
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        315..367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        444..489
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        490..514
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   830 AA;  93281 MW;  D4BF98D526F2E98E CRC64;
     MVEKILGESK ENNKWQIVSY GKSKQLPKTI ANANSSRPRK HEPIKTSSPN AAAIQATRSA
     IVLQNNQNRQ RGEAKVNCEK VVHLPLHRHE SQSHHQPFTY QSLQKDLKKS FKSVQPQSQP
     HPQQLQQHHR KRSKLQQQIK RAHRHLLTSC GIDKQQTPKS GNSNALIPTT HSVSRNTAQC
     CQTSRNSCHL SLKKGTGTHK LKNSKNTKEI HSNNKNNNKL PRNSNSQQQL KGKASKSSKQ
     KKLKSFVSDQ DSIISSRWCS IEEQLDLLDK LLYYCDEEEN AALRAWYNSI DKEFLFDSDS
     SEDKQRDDEG NQEGISDSDW SWSDMMSSSS LTSTTTAAPS EDDARSTVSN NNSMSSSCSS
     SLTPSSLKRR GHQHHPRFSG TRRPNVPPNV QEILAALYKN SETESASQLP TLADVEVPFD
     DSLVNYPDEP EDDPEMAQRI KASLNLPLTD SVTTSMGSNS PTPTDDSSML DEGIIQTSTS
     ASSSAIQPLK EKKSRTKRDK AEKGSGDASK EKKSKRSKKD KTKRASACLD SMGDVTAATS
     ISDVASAATD EGIAIDDDDL QSAEWANLRC TSEAAEIVAE REARRNKNRC ADYPGLAFGR
     SIFSSDTMMK FNIIRNELHN IMNTQLKRAE SEVAALNRRI QLLEEDLERS EERLGSATAK
     LSEASQAADE SERARKILEN RALADEERMD ALENQLKEAR FLAEEADKKY DEVARKLAMV
     EADLERAEER AEQGENKIVE LEEELRVVGN NLKSLEVSEE KANQREEEYK NQIKTLNTRL
     KEAEARAEFA ERSVQKLQKE VDRLEEEVSK SKEKYKNIAQ ELEYAELNNY
//