ID A0A1I8Q7Z5_STOCA Unreviewed; 1976 AA.
AC A0A1I8Q7Z5;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=Protein sprint {ECO:0008006|Google:ProtNLM};
GN Name=106081128 {ECO:0000313|EnsemblMetazoa:SCAU014730-PE};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU014730-PE, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU014730-PE}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU014730-PE};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RIN (Ras interaction/interference) family.
CC {ECO:0000256|ARBA:ARBA00006919}.
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DR RefSeq; XP_013098329.1; XM_013242875.1.
DR STRING; 35570.A0A1I8Q7Z5; -.
DR EnsemblMetazoa; SCAU014730-RE; SCAU014730-PE; SCAU014730.
DR GeneID; 106081128; -.
DR KEGG; scac:106081128; -.
DR VEuPathDB; VectorBase:SCAU014730; -.
DR OrthoDB; 5483004at2759; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR CDD; cd01776; RA_Rin; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR Gene3D; 1.20.1050.80; VPS9 domain; 1.
DR InterPro; IPR000159; RA_dom.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR InterPro; IPR003123; VPS9.
DR InterPro; IPR045046; Vps9-like.
DR InterPro; IPR037191; VPS9_dom_sf.
DR PANTHER; PTHR23101:SF104; PROTEIN SPRINT; 1.
DR PANTHER; PTHR23101; RAB GDP/GTP EXCHANGE FACTOR; 1.
DR Pfam; PF00788; RA; 1.
DR Pfam; PF00017; SH2; 1.
DR Pfam; PF02204; VPS9; 1.
DR SMART; SM00314; RA; 1.
DR SMART; SM00252; SH2; 1.
DR SMART; SM00167; VPS9; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR SUPFAM; SSF109993; VPS9 domain; 1.
DR PROSITE; PS50200; RA; 1.
DR PROSITE; PS50001; SH2; 1.
DR PROSITE; PS51205; VPS9; 1.
PE 3: Inferred from homology;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 676..769
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT DOMAIN 1717..1859
FT /note="VPS9"
FT /evidence="ECO:0000259|PROSITE:PS51205"
FT DOMAIN 1875..1963
FT /note="Ras-associating"
FT /evidence="ECO:0000259|PROSITE:PS50200"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 336..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..511
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 857..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 973..998
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1150..1227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1250..1273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1299..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1340..1364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1378..1421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..25
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..200
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 208..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..656
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1101
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1175..1220
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1250..1270
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1340..1361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1378..1401
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1976 AA; 215024 MW; DA3738C83A71B1DC CRC64;
MTTDEVILRR DRAAENGEEY REPPPRIRGQ STYLALLSSL ATDLDIMLND LRSSPSSRLS
SNSHHLQPRS ASSTYTPFTL NLGTSPTSPH ESTSSPVTVT NHSSQQLYRH NALRSNYQQH
TEQKSHREES SDNSQACNYR TNQHRQQQQQ SKDSQSSSPS RGTVEQQRQS PLSANRNQQH
QQRFNQNADK GSSSASSWLH GPQHDRDANS DSNNNNNKSH NSSQNSEEIF SFAGPAKTGS
CANGNDSNNS STTTPFQGFS TDVTRVSKLP LYTYQHKQLQ QPQTLHIKLL QQQQATKAIA
SQVTDAQTQN VVNRHKMMAT TRMTATMAAV SSTEVSAVPG SGTTGNSSNC TSHGLATNNN
SKTTTTTTSN TSTRTTTTNP LSTTSTSLDF RIKSSISTTQ QRGAVGRSAS GNGDSTHICN
INSSASSSSA TACTSWQLQS TSSTTTATST SFFRSSDSTL TASASQTAST TVGPNNQLKS
NSSNSTATTP TTNNNNNNVS SSNSSGGGLN SHQRLPFCGL DSIKGSDNNG SDGSMGGNGS
VVGGVGAATI SCGGKSNLSF DLNLQNGSKG SHGLSSAAGH IMPLVTDNGS EQFHSLDATD
SCGDGQFEDD MQALLPKCSR LSRDELSQSR TSLVSSSDGG ILAEGETSSE TSRGSDDSPP
CDLGLVERLL LTHPMWFLPG IQRSGAVHFL QGKEEGNFIV RGSSQPNTMA VSVRLPPDTG
PYIEHYLIQS NDGILCLESS RFKFDSIPSL IAHYAQCCDE LPVQLVLPRA LREVKNRQQL
SSLALLGQEF WRYPMSCPKS TDQEATFLDA KSPNSITETS GIGTTIFSNS GGSSSATGVM
QNGKVFSPIS NATGIFSQAG TPSDTNSSMS SFTTSGGQNM QLMSPESVDS VILTMSPVDI
NNQRNGILGL GQSSADNFKT SCNNLSTFKS NAIQNAPQNN FKNSTKNIME QEIRTQRPKP
PNTLNLDLRK AAPAPPMRWS KPLSPNSPQP PTDINGLNAA NNFTVTTTVT FSVDNASTPQ
FVEVTTPAAN NALTSVINSN TTFQTFSKRL SPEGECKDTM SSQGSSGGSR WQSHSSKDSN
SSQRKAPSPG TPTNALSTGG GKPRKSKTRK ESKHYQESDI LESPEIYCRS TLHDKISDYE
DLWSHDPSDR TGLLTSFKPP PDGQQGKRPD LLAETPPITS SSNTSATTPA VTTCPPLPHT
ADSLTMMSSE TTSDTQQLLK FSEDSKPRSR AGLILPGLMT QSLSEDQVFK SEATEGDTTP
TQTPVSRSKQ GSPFYAEPAD ALKQAGLATA SILRRSQRGP LLPANHRHSE PPKGGFVRTP
MCPMLVPAEI EKIAGSLDEL KKKQQQQSQA QPQQQPSKRA RGRFEQWQLD SSWEFMAKGD
HNEGEYGDYD SAEHWKEPTT GDNPNKENSL NREANKENKQ KPLTIHQIIA KRHPDLNLPE
LVRCSTPPQQ NQQAVANKNL NELNGSQKSF ELSQNNTCRL SSYDNVERNY ALSQCFFNGM
DSAQSDDGTV FSEPWDSSQW DSFLPHDDTT LNSDTIHLSK CRPALSEDDT IIEELSTKEL
NSQDTLKPKK TGGKHATILR NPSIRDREIL CHPRNKINLY NGGPGDTVRD YTLLLASDQC
TTFARNIENF ISCTKESREA APQVVMRNMR QFMNGMKNYL VKHGEGKFHQ EVESARSRLK
SDEFLNLDAI LETVMHQLVV LPLREHLYGM FVDYYTRSED IQLLAQNVKY ACGRAANDFG
IRSSVTPPSS NSLQIISNLL LRLQEAELPL EKLELFLCVI STIFDATGCP RGQQLGADDF
LPILVYVVAK CGFVGAEIEA EFMWGLLQPT LLNGEPGYYL TALCSAVHVL KSFMASENES
GTGSLDWRSS SLPACSSVLR VIIPDECNGS LQTRTLPVRP HTTTREVCRI IAHKARITNP
QDYALFKLVD GEETPLNDNE CPQDIRLAAK GKHCMLAYKR IDAKIAWPTA TQPNFN
//
