ID A0A1I8Q9L3_STOCA Unreviewed; 3804 AA.
AC A0A1I8Q9L3;
DT 18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT 18-JAN-2017, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Neurobeachin {ECO:0008006|Google:ProtNLM};
GN Name=106083452 {ECO:0000313|EnsemblMetazoa:SCAU015117-PG};
OS Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC Muscidae; Stomoxys.
OX NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU015117-PG, ECO:0000313|Proteomes:UP000095300};
RN [1] {ECO:0000313|EnsemblMetazoa:SCAU015117-PG}
RP IDENTIFICATION.
RC STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU015117-PG};
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
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DR RefSeq; XP_013101933.1; XM_013246479.1.
DR EnsemblMetazoa; SCAU015117-RG; SCAU015117-PG; SCAU015117.
DR VEuPathDB; VectorBase:SCAU015117; -.
DR Proteomes; UP000095300; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR046851; NBCH_WD40.
DR InterPro; IPR010508; NBEA-like_DUF1088.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR046852; Neurobeachin_a-sol.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF160; NEUROBEACHIN; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF06469; DUF1088; 1.
DR Pfam; PF15787; DUF4704; 2.
DR Pfam; PF20426; NBCH_WD40; 1.
DR Pfam; PF20425; Neurobeachin; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 3004..3112
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 3131..3420
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 3716..3747
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 998..1068
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1321..1386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1423..1444
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1529..1549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1630..1755
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2012..2038
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2058..2293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2455..2517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2546..2600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2688..2716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1159..1204
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1020..1049
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1121..1141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1332..1361
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1386
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1531..1549
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1648..1747
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2017..2033
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2058..2196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2204..2226
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2234..2257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2273..2293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2569..2589
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3804 AA; 424491 MW; 0F1DB08441449BEF CRC64;
MDSLERIMRA APLPRALSVN TATTKGQQRA LVHASLAAAT VGRKGRHLTG TFCLTGDTME
GIIQCLVFLK AFSLVGGEFD MELNFVIQDA QNIKHMLELL DHCPPNLQAE IWSVFIAILR
KSVRNLQACT DVGLIEHVLV RLQRSETVVA DLLIEMLGVL ASYSITVKEL KLLFGTMKAV
NGKWPRHSAK LLNVLRQMPH RNGPDVFFSF PGRKGSAMVL PPLAKWPYEN GFTFTTWFRL
DPINSVNIER EKPYLYCFKT SKGVGYTAHF VGNCLVLTSM KVKGKGFQHC VKYEFQPRKW
YMIAIVYIYN RWTKSEIKCL VNGQLASSTE MAWFVSTNDP FDKCYIGATP ELDEERVFCG
QMSAIYLFSE ALTTQQICAM HRLGPGYKSQ FRFDNECYLN LPDNHKRVLY DGKLSNAIVF
MYNPVATDGQ LCLQSAPKGN VSYFVHTPHA LMLQDVKAVV THSIHCTLNS IGGIQVLFPL
FSQLDMAHEG ISDIKRDPTL CSKLLGFICE LVETSQTVQQ HMIQNRGFLV ISFMLQRSSR
EHLTLEVLGS FLNLTKYLVT CLSANSDLLL KQLNLGLRYP FKRFYQLFCF SFLTWQLLDH
VLFNPALWIY TPANVQARLY SYLATEFLSD TQIYSNVRRV STVLQTVHTL KYYYWVVNPR
AKSGIVPKGL DGPRPAQKDI LAIRAYILLF LKQLIMIGQG VKEDELQSIL NYLTTMHEDE
NLHDVLQMLI SLMSEHPSSM VPAFDVKHGV RTIFKLLAAE SQLIRLQALK LLGFFLSRST
YKRKYDVMSP HNLYTLLAER LLLYEESLSM PTYNVLYEIM TEHISQHIMY NRHPEPESHY
RLENPMMLKV VATLIRQSKQ TESLIEVKKL FLSDMTLLCN SNRENRRTVL QMSVWQEWLI
AMAYIHPKNT EEQKISDMVY SLFRMLLHHA IKYEYGGWRV WVDTLAIVHS KVSYEEFKLQ
FAQMYEHYER QRTDQITDPA LRQARPISTI SGWEREEMQQ QHGTAVVHNA TSVASLEDVP
PVEEEVEEMD MEEEEAHQDE EEEVEETPNP NDDETKCACA NEEKPVDATS HQVIADEVEM
EMEPEPREDA AIKSSISNIS DVYNEHIKSE VLVVSTVQCN GNASSSASTS ANATPAKTLN
PSAASGPEAL KKTLNIEDLE ELELENAKAA ANIEDAEAHV EHVLQSSEKV LQECKMVADE
LQHEASSVIK DEEIELAVNE VVQGVLNNEK KQIKEPSLEM TTTIAAAAAA VTTTTTPATI
TKEVEDNANT VNEDAEVNDK VTMLNTKNLL NNNITEAEKV TETETQSNKT KADTEISAAA
QEINANINTP TKEEDDTNRP QKEGNNDDDE ETKKTEQTQE TKKENLLNNN QLPIEESQNV
TEAATTAAET TKLPAVVAET EMPAIKTQDL VVLEVSSSLP TTITGETSEE ISSLSPDTTI
SSPSMMDDAP LLNLNDESAS EEAKVETVVK DIVDELIDRV IEETNNNDVN KEQQSEVVPE
EFLNETAQEI IEDVLQSAVD QASSLEAEVP ALEKKTSEET AASLTKPDME EVELEENVAA
IVQTVVDDLV DQTVNSIVDT AIEEHAVMEE IATQVEDLKI IDSIIDQAEE ETQTSVEDLH
HKSALQATME ADAQTTDAEE YVETAPSVGV SQHEQQTQTQ QTEELADMEQ TQQPQQDQHH
QHQHQQQQSA STQVDNQHFD NTKQSAAHNQ QQQQQHQQQS QSQQQQPQPS QQQQQQRSKS
GSTRPMFSPG PTRPPFRIPE FKWSYIHQRL LSDVLFSLET DIQVWRSHST KSVLDFVNSS
ENAIFVVNTV HLISQLADNL IIACGGLLPL LASATSPNSE LDVLEPTQGM PLEVAVSFLQ
RLVNMADVLI FATSLNFGEL EAEKNMSSGG ILRQCLRLVC TCAVRNCLEC KERTRYNVGA
MARDVPGAAH LQALIRGAQA SPKNIVESIT GQLSPVKDPE KLLQDMDVNR LRAVIYRDVE
ETKQAQFLSL AIVYFISVLM VSKYRDILEP PAEPQIQRQS PVMQRSSGEP SGRPLFPQWS
HHVYPQFLPG THHNHVTTAN MQQQQQQQQQ QANMQQHQQQ QQQQHHQHHQ QQQQMYYHQQ
MPSPPPHQHQ QTASMQQQTA HLQHNHHHLT HQQQQLQQYY QSHHQAMNNA AASSYAAHCP
SPPLATQSTS PSTSSTTNTS QPASTSSLSS LASQPHHRHG GQKHQQQQQQ QQQQHYQQQQ
QHAAGGNVGP ASHHYTMMNG SQVLNGKIST PQPYSNAELN GGGGAVGGYH HHAHMQQQQQ
PAYMRTPSTS ASTSSMMMNG LNGGTSHQNG IVDYHSQHGG AGVGGGGGGG GMLNGVVANG
NNPGLIHATN NGGVANNNNG NNHNSMTMNN GRNMRNGGHV LSSGVVGPGM HASMGGGLTA
TNAVGGGGVG LMGSYKNNNG LNNNYRYNGR TTSGTGRTIQ DGDYEIIVVD ENNPSVLADN
DSHSSGPPSI KSPKMPTKSQ TIATATPTPP SSSTTLTKTS PKGATTMATT NATTTTTTTT
TTITNTVKSI TTTINSVLLN NSTTTSATNK LQQQPLSPPK PVVPQKLPKS DSECNSLNMN
STENEVPEVE SSSEIMVDDN KPINSNDESW TDVNLNEDAG VQATATGIIM PGGSGSGAGV
EVGKMRVGDD GSGMHSVHAA HLQHSQHGVS ERGDKPDSEI SVVRVPDGYT NASGAGGNSA
NVGGVQRGSR PDDLPMKPPL VGQLPMTTPS REASLTQKLE VALGPVCPLL REIMVDFAHY
LSKTLVGSHG QELLMEGKGL TTFKNSHSVV ELVMLLCSQE WQNSLQKHAG LAFIELINEG
RLLSHAMKDH IVRVANEAEF ILNRMRADDV LKHADFESQC AQTLLERREE ERMCDHLITA
ARRRDNVIAS RLLEKVRNIM CNRHGAWGDS SGAVQKQTYW KLDAWEDDAR RRKRMVQNPR
GSSHPQATLK AALENGGPED AILQTRDEFH TQIAVSRAHQ ATQHTADLLD DAELLIEDRE
LDLDLTGPVN ISTKAKLIAP GLVAPGTVSI TSTEMFFEVD EDHPEFQKIE PEVLKYCDHL
HGKWYFSEVR AIFSRRYLLQ NVALEIFLAS RTSILFAFPD QHTVKKVIKA LPRVGVGIKY
GIPQTRRASM MSPRQLMRNS NMTQKWQRRE ISNFEYLMFL NTIAGRTYND LNQYPIFPWV
LTNYETKDLD LSLPSNYRDL SKPIGALNPS RRAYFEERYE SWESDTIPPF HYGTHYSTAS
FTLNWLVRVE PFTTMFLALQ GGKFDYPDRL FSSVNLSWKN CQRDTSDVKE LIPEWYFLPE
MFYNSSGYRL GHREDGALVN DIELPPWAKT PEEFVRINRM ALESEFVSCQ LHQWIDLIFG
YKQRGPEAVR ATNVFYYLTY EGSVDLDGIA DPVMREAVEN QIRNFGQTPS QLLMEPHPPR
SSAMHLSPMM FSAMPDDLCQ ILKFYQNSPI IHISANTYPQ LSLPSVVTVT AGHQFAVNRW
NCNYTASVQS PSYADSNQQQ GAVKPLAIDP VLTAAQNTTH NNPMNRRHLG DNFSQMLKIR
SNCFVVTVDS RFLIACGFWD NSFRVFNTES AKIVQIVFGH FGVVTCLARS ECNITSDCYI
ASGSADCTVL LWHWNARTQS IVGEGDVPTP RATLTGHEQA VTSVVISAEL GLVVSGSTNG
PVLIHTTFGD LLRSLDAPMD FHSPELIAMS REGFIVVNYD KGNVAAYTIN GKELRHETHN
DNLQCMLLSR DGEYLMTAGD RGIVEVWRTF NLAPLYAFPA CNAGIRSLAL THDQKYLLAG
LSTGSIVVFH IDFNRWHHEY QQRY
//
