ID   A0A1I8QAI2_STOCA        Unreviewed;       918 AA.
AC   A0A1I8QAI2;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   28-JUN-2023, entry version 31.
DE   RecName: Full=TAFH domain-containing protein {ECO:0000259|PROSITE:PS51119};
GN   Name=106090822 {ECO:0000313|EnsemblMetazoa:SCAU015379-PC};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU015379-PC, ECO:0000313|Proteomes:UP000095300};
RN   [1] {ECO:0000313|EnsemblMetazoa:SCAU015379-PC}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU015379-PC};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF4 family.
CC       {ECO:0000256|ARBA:ARBA00006178}.
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DR   RefSeq; XP_013112602.1; XM_013257148.1.
DR   AlphaFoldDB; A0A1I8QAI2; -.
DR   EnsemblMetazoa; SCAU015379-RC; SCAU015379-PC; SCAU015379.
DR   GeneID; 106090822; -.
DR   VEuPathDB; VectorBase:SCAU015379; -.
DR   OrthoDB; 2910924at2759; -.
DR   Proteomes; UP000095300; Unassembled WGS sequence.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   GO; GO:0006366; P:transcription by RNA polymerase II; IEA:UniProt.
DR   CDD; cd08045; TAF4; 1.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   Gene3D; 1.20.120.1110; TAFH/NHR1 domain; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR045144; TAF4.
DR   InterPro; IPR007900; TAF4_C.
DR   InterPro; IPR037249; TAFH/NHR1_dom_sf.
DR   InterPro; IPR003894; TAFH_NHR1.
DR   PANTHER; PTHR15138; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR   PANTHER; PTHR15138:SF14; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4; 1.
DR   Pfam; PF05236; TAF4; 1.
DR   Pfam; PF07531; TAFH; 1.
DR   SMART; SM00549; TAFH; 1.
DR   SUPFAM; SSF47113; Histone-fold; 1.
DR   SUPFAM; SSF158553; TAFH domain-like; 1.
DR   PROSITE; PS51119; TAFH; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          247..343
FT                   /note="TAFH"
FT                   /evidence="ECO:0000259|PROSITE:PS51119"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          134..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          604..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          854..886
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          781..839
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        134..249
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        604..624
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        625..643
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   918 AA;  99158 MW;  859102896E8D934B CRC64;
     MLPAGVVVGM RPPASQQQPK NVQGNTMGRV VIGGPHMVGT RPQSPAITLS TLTPGQTPAL
     ILKTENGFQL LRVGTATSGP VTQTIGTNST NPTQIRLQTV PAASISNTST ANNIVVNSVA
     NSNSQPTHVY TSQANISSLQ SHQQQTTTNV VTSMQHQQQH HQQQSQQQQQ FHTQTQHLQS
     QPQITQIQTI PAHQTTSGHL QQQHSQNQQH GNTNSTMNNV VNSTNSVSSG ATSVTTTTTT
     PQSAAAQGNT KEKCRKFLAN LIDLSTREPK PVEKNVRNLI QELVNANVEP EEFCDRLERL
     LNASPQPCLI GFLKKSLPLL RQALFTKELV IEGIKPPPQH VVGGITIQQQ LPKIQAQIRP
     ISQNQTTTIG QTQVRMISPA SAPRPIGHTT ITKQPAGGIR IQGPANGPRL INTQIRGPMS
     QQTTTAQLQT QSTHANIVQI RAPTATQMNR PATVQIRAPK AKNTTTATAS PGITHVKVGQ
     TQIKAISSSS PAISSQPPSL AAISNNVPTG SNLSSSASIL STINSVASNS ICSVSGLPIP
     SLPTVQLPPA VLAQQQQQQQ QLQLNSTHSL ISTNASSSLD HIKTEIKTEN MKSSGGITTI
     IAAPSTPTQA NKAPAKTSNA SASKAAAKKK RDLADKERDE SKLNNTTSAA SSAASFFQQP
     SISMSSYGDD DINDVAAMGG VNLAEETQRI LGCTENIGTQ IRSCKDEVFL HLPALQARIR
     AMVMERGLEE PSQDVAVLIS HACQERLKNI VEKLAVIAEH RIDVIKLDPR YEVTKDVRGQ
     IKFLEELDKA EQKRHEELER EMLLRAAKSR SKIEDPEQAK MKARAKEMQR AEMEELRQRD
     ANMTALQAIG PRKKLKLDGD GTGSGLGSGT GNVLGPSGTA PAPLRPRIKR VNLRDMLFFM
     EQERETCRSQ MLYKAYLK
//