ID   A0A1I8QBI1_STOCA        Unreviewed;      1101 AA.
AC   A0A1I8QBI1;
DT   18-JAN-2017, integrated into UniProtKB/TrEMBL.
DT   18-JAN-2017, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=BPL/LPL catalytic domain-containing protein {ECO:0000259|PROSITE:PS51733};
GN   Name=106086242 {ECO:0000313|EnsemblMetazoa:SCAU015647-PA};
OS   Stomoxys calcitrans (Stable fly) (Conops calcitrans).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Muscidae; Stomoxys.
OX   NCBI_TaxID=35570 {ECO:0000313|EnsemblMetazoa:SCAU015647-PA, ECO:0000313|Proteomes:UP000095300};
RN   [1] {ECO:0000313|EnsemblMetazoa:SCAU015647-PA}
RP   IDENTIFICATION.
RC   STRAIN=USDA {ECO:0000313|EnsemblMetazoa:SCAU015647-PA};
RG   EnsemblMetazoa;
RL   Submitted (MAY-2020) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the biotin--protein ligase family.
CC       {ECO:0000256|ARBA:ARBA00009934}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   RefSeq; XP_013106279.1; XM_013250825.1.
DR   AlphaFoldDB; A0A1I8QBI1; -.
DR   EnsemblMetazoa; SCAU015647-RA; SCAU015647-PA; SCAU015647.
DR   VEuPathDB; VectorBase:SCAU015647; -.
DR   OrthoDB; 317678at2759; -.
DR   Proteomes; UP000095300; Unassembled WGS sequence.
DR   GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR   GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR   InterPro; IPR003142; BPL_C.
DR   InterPro; IPR004143; BPL_LPL_catalytic.
DR   NCBIfam; TIGR00121; birA_ligase; 1.
DR   PANTHER; PTHR12835; BIOTIN PROTEIN LIGASE; 1.
DR   PANTHER; PTHR12835:SF5; BIOTIN--PROTEIN LIGASE; 1.
DR   Pfam; PF02237; BPL_C; 1.
DR   Pfam; PF03099; BPL_LplA_LipB; 1.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
PE   3: Inferred from homology;
KW   Ligase {ECO:0000256|ARBA:ARBA00022598}.
FT   DOMAIN          831..1025
FT                   /note="BPL/LPL catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51733"
FT   REGION          209..256
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          287..500
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        226..256
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..312
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        336..372
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        373..414
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        427..490
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1101 AA;  122598 MW;  E1478D01C1D3061F CRC64;
     MLTLYYVSAT FLQSWRINKI CQKISEQLSQ QATIAFYALP QNRDDGFYSR LATSELCQNR
     QVAKVTEILW LHDHYRGCCL MPLQSLHTSA WISFPEAPGL LPFHFGKAPE SLQRSLSLDR
     HGGLIRLLLE TETTPCYDAE LWQKDIVRIE NYAVKNDGDP QPYSLLCSHL RKPVRSAEEC
     LPEDWAKHLE DLRALSVLAN QAIEYTSSKS RNEPKATTGA IKPDLIPQEK RSEIEIKKEK
     ESPKKPQKAM NKTLEEVPEI SKKDVLADVK PAEVKLAVRD TEKFIKAEQT NETKPNEAKT
     SPNVQQASPS KLRAKPTEIR KPGALDTGRF KTTKASENLI EAESKKSSEL ERIAASKAAE
     ISKSKSPTKD NEAKYAKQPS TTLTSSSPAV AGQNDVPSTK STASLSQVTK DQEKTPKIPQ
     VAEPLSEPTK SIPTDSIPKI ESVDKTASKT TTPATTTAAS SNINTPKPTV ATTTASVSSA
     GITSSPLKDN TKRPSLKRHK DSIKECKPLN VLVYAETATA RESAITILKE ILAENTYTIY
     PMTQQQVEQQ HWLNTTALLV VCGSVVNSMG ELFVDYFLHG GKVLSLCSDV LHFILPTYRT
     AEVREHELVQ FSYDKWQKVK MMHHIFCYQP SPVKKNFSTD SDDSAHATNR KPALVCLPRS
     VELKDLKGHL HRLDVKVLGT EETWNTPSLL LAHNQKSGGS AVFSQVHLEI SPSEFESDEA
     KYSILKQNDK IRHEIFSDLL KNHLSLSVKS EKVNANGSGP KCVFKKAYFL GKHEAKFELL
     GKLKDKCDGD NVIATPNLMI KFCGPDDKLP NVNSNILPIL IHSCPEDFST VDYFDNLKTR
     YVGRLVIYAP VVSSSQHVVA DLELSNGIAV IPRQQTDGVG RSNNQWLSPL GCVMYSIQLH
     VSLNSPLGKR LPLLQHVIGA AMVHTLKGHD QYKVLNIGLK WPNDAYANGV TKIGGLMVRT
     TLNGTNAIVN IGCGINLDNS KPTICVNDMI REYNHANQKN LPLLKYEQFI AMMFNEIEQL
     VELIQNGDFD KFYKIYYDLW LHSDQSISIC DKDGSTKDVK ILGIDEYGFL QVKLANGLTE
     IVHPDGNSFD ILKGLIVPKF N
//