ID A0A1I9LSX7_ARATH Unreviewed; 332 AA.
AC A0A1I9LSX7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Nuclear transcription factor Y subunit {ECO:0000256|RuleBase:RU367155};
GN Name=NF-YA2 {ECO:0000313|EMBL:ANM65685.1, ECO:0000313|TAIR:AT3G05690};
GN Synonyms=ATHAP2B {ECO:0000313|EMBL:ANM65685.1}, AtNF-YA2
GN {ECO:0000313|EMBL:ANM65685.1}, HAP2B {ECO:0000313|EMBL:ANM65685.1},
GN nuclear factor Y {ECO:0000313|EMBL:ANM65685.1}, subunit A2
GN {ECO:0000313|EMBL:ANM65685.1}, UNE8 {ECO:0000313|EMBL:ANM65685.1},
GN UNFERTILIZED EMBRYO SAC 8 {ECO:0000313|EMBL:ANM65685.1};
GN OrderedLocusNames=At3g05690 {ECO:0000313|Araport:AT3G05690,
GN ECO:0000313|EMBL:ANM65685.1};
GN ORFNames=F18C1.4 {ECO:0000313|EMBL:ANM65685.1}, F18C1_4
GN {ECO:0000313|EMBL:ANM65685.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000313|EMBL:ANM65685.1, ECO:0000313|Proteomes:UP000006548};
RN [1] {ECO:0000313|EMBL:ANM65685.1, ECO:0000313|Proteomes:UP000006548}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=11130713; DOI=10.1038/35048706;
RG European Union Chromosome 3 Arabidopsis Sequencing Consortium;
RG Institute for Genomic Research;
RG Kazusa DNA Research Institute;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Blocker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M.,
RA Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N.,
RA Artiguenave F., Robert C., Brottier P., Wincker P., Cattolico L.,
RA Weissenbach J., Saurin W., Quetier F., Schafer M., Muller-Auer S.,
RA Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N.,
RA Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P.,
RA Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S.,
RA Simionati B., Conrad A., Hornischer K., Kauer G., Lohnert T.H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schon O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwalder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.W., Mayer K.F., Kaul S.,
RA Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2] {ECO:0000313|Proteomes:UP000006548}
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia {ECO:0000313|Proteomes:UP000006548};
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Component of the sequence-specific heterotrimeric
CC transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3'
CC box motif found in the promoters of its target genes.
CC {ECO:0000256|RuleBase:RU367155}.
CC -!- SUBUNIT: Heterotrimer. {ECO:0000256|RuleBase:RU367155}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367155}.
CC -!- SIMILARITY: Belongs to the NFYA/HAP2 subunit family.
CC {ECO:0000256|RuleBase:RU367155}.
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DR EMBL; CP002686; ANM65685.1; -; Genomic_DNA.
DR RefSeq; NP_001327635.1; NM_001337602.1.
DR AlphaFoldDB; A0A1I9LSX7; -.
DR ProteomicsDB; 203526; -.
DR EnsemblPlants; AT3G05690.2; AT3G05690.2; AT3G05690.
DR GeneID; 819738; -.
DR Gramene; AT3G05690.2; AT3G05690.2; AT3G05690.
DR Araport; AT3G05690; -.
DR TAIR; AT3G05690; NF-YA2.
DR OrthoDB; 1119073at2759; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; A0A1I9LSX7; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR Gene3D; 6.10.250.2430; -; 1.
DR InterPro; IPR001289; NFYA.
DR PANTHER; PTHR12632:SF84; NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT A-2; 1.
DR PANTHER; PTHR12632; TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED; 1.
DR Pfam; PF02045; CBFB_NFYA; 1.
DR PRINTS; PR00616; CCAATSUBUNTB.
DR SMART; SM00521; CBF; 1.
DR PROSITE; PS51152; NFYA_HAP2_2; 1.
PE 1: Evidence at protein level;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU367155};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367155};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A1I9LSX7,
KW ECO:0007829|ProteomicsDB:A0A1I9LSX7};
KW Reference proteome {ECO:0000313|Proteomes:UP000006548};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367155};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU367155}.
FT REGION 215..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 231..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 36699 MW; EBC359FBABD69B0F CRC64;
MGFVIRVVLR NTQSQRTYLS YSSRHYLFFT FCNWNLEMAM QTVREGLFSA PQTSWWTAFG
SQPLAPESLA GDSDSFAGVK VGSVGETGQR VDKQSNSATH LAFSLGDVKS PRLVPKPHGA
TFSMQSPCLE LGFSQPPIYT KYPYGEQQYY GVVSAYGSQS RVMLPLNMET EDSTIYVNSK
QYHGIIRRRQ SRAKAAAVLD QKKLSSRCRK PYMHHSRHLH ALRRPRGSGG RFLNTKSQNL
ENSGTNAKKG DGSMQIQSQP KPQQSNSQNS EVVHPENGTM NLSNGLNVSG SEVTSMNYFL
SSPVHSLGGM VMPSKWIAAA AAMDNGCCNF KT
//
