ID A0A1J0GJK5_9CLOT Unreviewed; 595 AA.
AC A0A1J0GJK5;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:APC41586.1};
GN ORFNames=A7L45_16615 {ECO:0000313|EMBL:APC41586.1};
OS Clostridium estertheticum subsp. estertheticum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1552 {ECO:0000313|EMBL:APC41586.1, ECO:0000313|Proteomes:UP000182569};
RN [1] {ECO:0000313|EMBL:APC41586.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 8809 {ECO:0000313|EMBL:APC41586.1};
RA Yu Z., Gunn L., Brennan E., Reid R., Wall P.G., Gaora O.P., Hurley D.,
RA Bolton D., Fanning S.;
RT "Complete genome sequence of Clostridium estertheticum DSM 8809, a microbe
RT identified in spoiled vacuum packed beef.";
RL Front. Microbiol. 7:1764-1764(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP015756; APC41586.1; -; Genomic_DNA.
DR RefSeq; WP_071613878.1; NZ_CP015756.1.
DR AlphaFoldDB; A0A1J0GJK5; -.
DR STRING; 1552.A7L45_16615; -.
DR KEGG; ceu:A7L45_16615; -.
DR OrthoDB; 9809348at2; -.
DR Proteomes; UP000182569; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR42713; HISTIDINE KINASE-RELATED; 1.
DR PANTHER; PTHR42713:SF2; TWO-COMPONENT SENSOR KINASE YESM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:APC41586.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000182569};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 325..377
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 595 AA; 68116 MW; EE5C6AB036A81328 CRC64;
MNKFVKIFFD KSIKYKLSFY FSLVILIPIV TISILGNLLY KNSITNQQNE NIRQMVSQIS
NNIDFYIKDT ENIINYLSED PRILSFLCNN TNSSINKKDS DSMRVEESSK AINSFTTFHS
EIAGIMIVKQ DDTFVSDVMG RISRDALTKE KWYLDAAKNP ITMHLFSKPV GRNINNVFQY
SADDVVSMSK AVVDKKTGKC IGVILIDMKL DIIKSVIEHA KPAKNGFVYI VDNNGEIVYS
PVNKIVYRIK SEWTDNLSGE ILIKRIKEND YKIIHGNSTY TGWKTVEVFP LNESLKVIDS
LVYYSIIIAI ITLLIAEILA TFFTRSIVGP ISKLKRLMKK TEEGNFNVVF NSKYDDEIGE
LGNAFNNMVR EIKNLIMLVE TEAKKKRKAE ISILHAQIKP HFIYNTLDTI QWMAQEHDAQ
DIVDITYNLT NLLRIGLSAG EENIKISQEI KHVESYLLIQ KIRYEDKLNY EINMQKEILN
LSVIKLILQP IVENAIYHGI KEKRGSGHIK ISGMIENEKI CFVIQDNGIG IEDEKLMKIN
EMLKGKTTSN DVIGYGIFNV NEKIKLTYGE EFGLEYHSIY GEGTTVVLWH PIIKN
//
