ID A0A1J0LIR8_9FLAO Unreviewed; 489 AA.
AC A0A1J0LIR8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Putative Na(+)/H(+) antiporter {ECO:0000313|EMBL:APD06104.1};
GN ORFNames=UJ101_00565 {ECO:0000313|EMBL:APD06104.1};
OS Flavobacteriaceae bacterium UJ101.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1150389 {ECO:0000313|EMBL:APD06104.1, ECO:0000313|Proteomes:UP000183895};
RN [1] {ECO:0000313|EMBL:APD06104.1, ECO:0000313|Proteomes:UP000183895}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UJ101 {ECO:0000313|EMBL:APD06104.1,
RC ECO:0000313|Proteomes:UP000183895};
RA Oh H.-M., Yang J.-A., Yang S.-H., Kwon K.-K.;
RT "Complete Genome Sequence of Flavobacteriales bacterium UJ101.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NhaC Na(+)/H(+) (TC 2.A.35) antiporter
CC family. {ECO:0000256|ARBA:ARBA00038435}.
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DR EMBL; CP016269; APD06104.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J0LIR8; -.
DR KEGG; fbu:UJ101_00565; -.
DR OrthoDB; 9762978at2; -.
DR Proteomes; UP000183895; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR004770; Na/H_antiport_NhaC.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR NCBIfam; TIGR00931; antiport_nhaC; 1.
DR PANTHER; PTHR33451; MALATE-2H(+)/NA(+)-LACTATE ANTIPORTER; 1.
DR PANTHER; PTHR33451:SF3; MALATE-2H(+)_NA(+)-LACTATE ANTIPORTER; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 3: Inferred from homology;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000183895};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..104
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..481
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 166..480
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 489 AA; 52325 MW; 6F39372E2FAA728E CRC64;
MHMRQERPIS LIESLIPIVV LIFFLAVNYQ VFGDGAAEGP NQFGLILGAG TAMIIAYFIK
IPFSKILEGI SENIRETVPA ILILLLVGAL AGTWMLSGIV PAMIYYGMQI LNPTIFLFAS
VIIAALVSIA TGSSWTTSAT IGIALIGIGN SLGIDSAMTA GAVISGAYFG DKMSPMSDTT
NLAPAMAGTD LITHIKYMTI TTFPSIVITL ILFLFLGFSL ETNGGVSSDE MLQAMAGRFN
ITPWLFVVPI VVVGLIIRKI KPFVALLIGV LLGVLFALIF QQELMSDLIK IAAGETGDAS
LNVKSIYQLS MQTITGDLYI ETGNAVLDDR QLFSSGGMAG MLNTIFLIVS AMIFGGAMQA
IGALEKLSYE LLRVAKGVFG LFASTVASCI GLNVLASDQY LAIVVPGRMF KEAYREKGLA
PENLSRTLED SGTVTSVLIP WNTCGAYQST VLTVDVMAYL PYAFFNLISP FMTLLIAAIG
YKIRKLKES
//
