ID   A0A1J0LWR8_THEBO        Unreviewed;       736 AA.
AC   A0A1J0LWR8;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=ATP-dependent Clp protease ATP-binding subunit ClpA {ECO:0000313|EMBL:APD10051.1};
GN   ORFNames=A0O31_01979 {ECO:0000313|EMBL:APD10051.1};
OS   Thermus brockianus.
OC   Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX   NCBI_TaxID=56956 {ECO:0000313|EMBL:APD10051.1, ECO:0000313|Proteomes:UP000182993};
RN   [1] {ECO:0000313|Proteomes:UP000182993}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GE-1 {ECO:0000313|Proteomes:UP000182993};
RA   Schaefers C., Blank S., Wiebusch S., Elleuche S., Antranikian G.;
RT   "Whole genome sequencing of Thermus brockianus strain GE-1.";
RL   Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP016312; APD10051.1; -; Genomic_DNA.
DR   RefSeq; WP_071677657.1; NZ_CP016312.1.
DR   AlphaFoldDB; A0A1J0LWR8; -.
DR   STRING; 56956.A0O31_01979; -.
DR   KEGG; tbc:A0O31_01979; -.
DR   OrthoDB; 9803641at2; -.
DR   Proteomes; UP000182993; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd00009; AAA; 1.
DR   CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR   Gene3D; 1.10.8.60; -; 2.
DR   Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003959; ATPase_AAA_core.
DR   InterPro; IPR019489; Clp_ATPase_C.
DR   InterPro; IPR036628; Clp_N_dom_sf.
DR   InterPro; IPR004176; Clp_R_dom.
DR   InterPro; IPR001270; ClpA/B.
DR   InterPro; IPR018368; ClpA/B_CS1.
DR   InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR   PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR   PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR   Pfam; PF00004; AAA; 1.
DR   Pfam; PF07724; AAA_2; 1.
DR   Pfam; PF17871; AAA_lid_9; 1.
DR   Pfam; PF02861; Clp_N; 2.
DR   Pfam; PF10431; ClpB_D2-small; 1.
DR   PRINTS; PR00300; CLPPROTEASEA.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM01086; ClpB_D2-small; 1.
DR   SUPFAM; SSF81923; Double Clp-N motif; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51903; CLP_R; 1.
DR   PROSITE; PS00870; CLPAB_1; 1.
DR   PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:APD10051.1};
KW   Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW   Hydrolase {ECO:0000313|EMBL:APD10051.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protease {ECO:0000313|EMBL:APD10051.1};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW   ProRule:PRU01251}.
FT   DOMAIN          1..143
FT                   /note="Clp R"
FT                   /evidence="ECO:0000259|PROSITE:PS51903"
SQ   SEQUENCE   736 AA;  81608 MW;  40F3382F8B1C8EDD CRC64;
     MNRYDDRARL VFHYAREEGS RLGHSMIGPE HLLLGLMREG GTAARILQEY GASLEAMRRM
     VEELVGRGEG SRTGEPPAIT PRARRVMELA SAEARNMGAS VIGTEHILLG IIREGDGIAY
     RILSHFAKDV DAIRWRVLSM AEGREREKPV NTPFLDEYGR DLTKEAREGK LDPVIGRQEE
     INRVIQILAR RTKNNPVLIG DPGVGKTAIV EGLAQAIVEG RVPPILRGAR VVAIDLAGVV
     AGTKYRGEFE ERLRQIIEEL KNAKVIAFID ELHTLIGAGG AEGTLDAANI LKPALARGEI
     QVIGATTTGE YHRYIEKDAA LERRFQPVIV LEPSPEETLE ILKGLRPRYE AHHGVIIPDE
     ILELSVKIGI RSLPGRNFPD KAIDLIDEAA SRVRLNASLG LPVAEEEDGT PVVTREDIEA
     VVDSWGGVYV DDKDDEKLMR LEEELRKRVV GQEEAIRALA SALRRARVGL GGRTRVAASF
     LFVGQSGVGK TQLAKALAEV LFGSERALIR FDMSEFQEPH SISKLIGAPP GYVGYEQGGR
     LTEAVRRQPF SVVLLDEIEK AHPDIYNTFL QVLDEGRLTD GMGRTVDFRR VILIMTSNTG
     YNVGPAIGFT SREVDTESPL KALFTPEFLD RLDEVIRFRP LTEEELVQVA RLMLEDIQKE
     LKSRDIEVAF APEVARFVVE QAPKTGSARA IRGVIRERIE DPLSLALLKK PTGRLYVTVE
     EDHLAFHEVE GEELLV
//