ID A0A1J0PCQ2_9SYNE Unreviewed; 372 AA.
AC A0A1J0PCQ2;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=S-(hydroxymethyl)glutathione dehydrogenase {ECO:0000256|ARBA:ARBA00021865};
DE AltName: Full=Alcohol dehydrogenase class-3 {ECO:0000256|ARBA:ARBA00030752};
DE AltName: Full=Alcohol dehydrogenase class-III {ECO:0000256|ARBA:ARBA00033399};
GN ORFNames=BM449_12640 {ECO:0000313|EMBL:APD48932.1};
OS Synechococcus sp. SynAce01.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Synechococcales; Synechococcaceae;
OC Synechococcus.
OX NCBI_TaxID=1916956 {ECO:0000313|EMBL:APD48932.1, ECO:0000313|Proteomes:UP000182608};
RN [1] {ECO:0000313|Proteomes:UP000182608}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SynAce01 {ECO:0000313|Proteomes:UP000182608};
RA Tang J., Daroch M., Liang Y., Jiang D., Shah M.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP018091; APD48932.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J0PCQ2; -.
DR STRING; 1916956.BM449_12640; -.
DR KEGG; syny:BM449_12640; -.
DR OrthoDB; 9806940at2; -.
DR Proteomes; UP000182608; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051903; F:S-(hydroxymethyl)glutathione dehydrogenase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006069; P:ethanol oxidation; IEA:InterPro.
DR CDD; cd08300; alcohol_DH_class_III; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR014183; ADH_3.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR02818; adh_III_F_hyde; 1.
DR PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000182608};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 189..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..368
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 372 AA; 38988 MW; 3980624A00B85B98 CRC64;
MIQSRAAVAW AAGEPLEITT IDVAPPQAGE VLLRVVASGV CHTDAYTLSG QDPEGLFPAV
LGHEGGAVVE ALGEGVTSLA VGDHVIPLYT PECRACSFCL SGKTNLCQAI RGTQGRGLMP
DGTSRFSKNG KPIYHYMGTS TFSEYTVVPE IAVAKISKRA PLEKVCLLGC GVTTGIGAVL
NTAKVEAGAT VAVFGLGGIG LAVIIGAVMA GASRIIGVDT NPEKFAVARQ LGASDCLDPT
QSQRPIQEVI AELTDGGVDY SFECIGNVEV MRAALECCHK GWGESTIIGV AGAGQEIATR
PFQLVTGRVW RGSAFGGVRG RSELPGYVER FEKGEIPLDT FITHTMPLEE INRAFDLMHA
GQSIRSVIHF NG
//
