ID A0A1J0VT25_9NOCA Unreviewed; 362 AA.
AC A0A1J0VT25;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Aryl-alcohol dehydrogenase {ECO:0000313|EMBL:APE35162.1};
GN ORFNames=BOX37_15765 {ECO:0000313|EMBL:APE35162.1};
OS Nocardia mangyaensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=2213200 {ECO:0000313|EMBL:APE35162.1, ECO:0000313|Proteomes:UP000183810};
RN [1] {ECO:0000313|EMBL:APE35162.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Y48 {ECO:0000313|EMBL:APE35162.1};
RA Jaros S., Januszkiewicz K., Wedrychowicz H.;
RL Submitted (NOV-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
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DR EMBL; CP018082; APE35162.1; -; Genomic_DNA.
DR RefSeq; WP_071928347.1; NZ_CP018082.1.
DR AlphaFoldDB; A0A1J0VT25; -.
DR KEGG; nsl:BOX37_15765; -.
DR OrthoDB; 334894at2; -.
DR Proteomes; UP000183810; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08278; benzyl_alcohol_DH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43350:SF19; RIBULOSE-5-PHOSPHATE REDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000183810};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 12..360
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 362 AA; 37298 MW; 1592815D92711CDC CRC64;
MRTTAVLSRD PKADFSIEPV EIDEPRSGEI LVRITAAGIC HTDLATRRAG AADRPVLLGH
EGAGLVEAVG PEVRTVRPGD PVVLTFRHCG ACANCAADRP AYCLRSVALN QFGRRGHDTP
RLTVDGAPIL DGFFGQSSFA GYALTTQDNT IVVDPAVDLA LAAPFGCGFQ TGAGAVLNVL
RPEPGAWLAV YGAGAVGMAA LLAARSIAGV HVAVVETSAA RRELALELGA DAALDPADGD
TVARIRELTG GGATHALDTT GIPAVLGEAV AALGIGATVV AVGLGLGTPP IDVSDIVLRG
KTIRGCLEGD SVPATFVPQL LDLHAEGRFP VERLITRYPH TDIATALADQ RAGRVVKPVL
TW
//
