ID A0A1J1A966_9EURY Unreviewed; 268 AA.
AC A0A1J1A966;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Prephenate dehydratase {ECO:0000313|EMBL:APE94652.1};
DE EC=4.2.1.51 {ECO:0000313|EMBL:APE94652.1};
GN Name=pheA {ECO:0000313|EMBL:APE94652.1};
GN ORFNames=HSR6_0179 {ECO:0000313|EMBL:APE94652.1};
OS Halodesulfurarchaeum formicicum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halodesulfurarchaeum.
OX NCBI_TaxID=1873524 {ECO:0000313|EMBL:APE94652.1, ECO:0000313|Proteomes:UP000186165};
RN [1] {ECO:0000313|Proteomes:UP000186165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSR6 {ECO:0000313|Proteomes:UP000186165};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Smedile F.,
RA Messina E., La Cono V., Yakimov M.M.;
RT "Discovery of first anaerobic lithoheterotrophic haloarchae widely
RT represented in hypersaline habitats.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR EMBL; CP016804; APE94652.1; -; Genomic_DNA.
DR RefSeq; WP_071932553.1; NZ_CP016804.1.
DR AlphaFoldDB; A0A1J1A966; -.
DR GeneID; 30416704; -.
DR KEGG; hhsr:HSR6_0179; -.
DR OrthoDB; 8755at2157; -.
DR Proteomes; UP000186165; Chromosome.
DR GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd04905; ACT_CM-PDT; 1.
DR CDD; cd13630; PBP2_PDT_1; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR001086; Preph_deHydtase.
DR InterPro; IPR018528; Preph_deHydtase_CS.
DR PANTHER; PTHR21022; PREPHENATE DEHYDRATASE P PROTEIN; 1.
DR PANTHER; PTHR21022:SF19; PREPHENATE DEHYDRATASE-RELATED; 1.
DR Pfam; PF01842; ACT; 1.
DR Pfam; PF00800; PDT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:APE94652.1};
KW Phenylalanine biosynthesis {ECO:0000256|ARBA:ARBA00023222};
KW Reference proteome {ECO:0000313|Proteomes:UP000186165}.
FT DOMAIN 2..171
FT /note="Prephenate dehydratase"
FT /evidence="ECO:0000259|PROSITE:PS51171"
FT DOMAIN 184..261
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 268 AA; 28576 MW; D85643B2B8D1DA87 CRC64;
MTTVTLGPEG TYSHRAATAV ADDEIAFTES VHSIVSGVAG GKFEQGVVPI ENSIEGSVTE
SLDALADADV AVTREIVTPI RHALLAQGED FATVASHSQA LAQCRDYLLG TYPEADLEAV
ASTASGVERA REDPTIAGIG HPDNAGDGLQ VLAEDIQDQN SNATRFFAIA GPEARSVSGG
KSSLIVYPNT NYPGLLLELL EPFADRDINL SRLESRPSGE RLGDYVFHID LEAGLYEERT
QAAIAEIEEF ASEGWVKRMG SYDVEHVV
//
