ID A0A1J1ABA8_9EURY Unreviewed; 281 AA.
AC A0A1J1ABA8;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Na+/Ca2+-antiporter-like protein {ECO:0000313|EMBL:APE95023.1};
GN ORFNames=HSR6_0561 {ECO:0000313|EMBL:APE95023.1};
OS Halodesulfurarchaeum formicicum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Halobacteriaceae; Halodesulfurarchaeum.
OX NCBI_TaxID=1873524 {ECO:0000313|EMBL:APE95023.1, ECO:0000313|Proteomes:UP000186165};
RN [1] {ECO:0000313|Proteomes:UP000186165}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HSR6 {ECO:0000313|Proteomes:UP000186165};
RA Sorokin D.Y., Kublanov I.V., Roman P., Sinninghe Damste J.S.,
RA Golyshin P.N., Rojo D., Ciordia S., Mena Md.C., Ferrer M., Smedile F.,
RA Messina E., La Cono V., Yakimov M.M.;
RT "Discovery of first anaerobic lithoheterotrophic haloarchae widely
RT represented in hypersaline habitats.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP016804; APE95023.1; -; Genomic_DNA.
DR RefSeq; WP_071932737.1; NZ_CP016804.1.
DR AlphaFoldDB; A0A1J1ABA8; -.
DR GeneID; 30417084; -.
DR KEGG; hhsr:HSR6_0561; -.
DR OrthoDB; 142185at2157; -.
DR Proteomes; UP000186165; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 1.
DR InterPro; IPR004481; K/Na/Ca-exchanger.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR PANTHER; PTHR10846:SF8; INNER MEMBRANE PROTEIN YRBG; 1.
DR PANTHER; PTHR10846; SODIUM/POTASSIUM/CALCIUM EXCHANGER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000186165};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..119
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 125..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 233..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..280
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..144
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 168..279
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
SQ SEQUENCE 281 AA; 28879 MW; 30D0D5E618F1D5BD CRC64;
MLVELALFVF GLALLVFGAD RAVTAAAGLA LFYGVSPFFV GVTVISIGTS VPEMVTSITG
ASFGAGDLVV GNIVGSETAQ ITIAIAIVAF IAPIIANRRN VLTYGSAMLL AMTVMLLALE
DGSIGRSEGV LMMLAYVQFV YILYTNEGGA EIGEEIEGRL SPREALPWII GGLMLVVVGS
QIMVTNGMAV ARIVGVPEYT IGLLTGLGTT LPEIAIAGLA ATRGQQGISV GSLLGSNVTD
PVFSLGIGAL FFEISVSNPE QVLLSASYMV LVSVAVLALM G
//
