ID A0A1J1HC38_PLARL Unreviewed; 544 AA.
AC A0A1J1HC38;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN ORFNames=PRELSG_1425100 {ECO:0000313|EMBL:CRH02520.1};
OS Plasmodium relictum.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Haemamoeba).
OX NCBI_TaxID=85471 {ECO:0000313|EMBL:CRH02520.1, ECO:0000313|Proteomes:UP000220158};
RN [1] {ECO:0000313|EMBL:CRH02520.1, ECO:0000313|Proteomes:UP000220158}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SGS1 {ECO:0000313|EMBL:CRH02520.1,
RC ECO:0000313|Proteomes:UP000220158};
RG Pathogen Informatics;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the importin alpha family.
CC {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR EMBL; LN835309; CRH02520.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1HC38; -.
DR VEuPathDB; PlasmoDB:PRELSG_1425100; -.
DR OMA; EMIQMLY; -.
DR OrthoDB; 916229at2759; -.
DR Proteomes; UP000220158; Chromosome 14.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032413; Arm_3.
DR InterPro; IPR000225; Armadillo.
DR InterPro; IPR002652; Importin-a_IBB.
DR InterPro; IPR024931; Importin_alpha.
DR PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR PANTHER; PTHR23316:SF71; IMPORTIN SUBUNIT ALPHA; 1.
DR Pfam; PF00514; Arm; 7.
DR Pfam; PF16186; Arm_3; 1.
DR Pfam; PF01749; IBB; 1.
DR PIRSF; PIRSF005673; Importin_alpha; 1.
DR SMART; SM00185; ARM; 8.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50176; ARM_REPEAT; 4.
DR PROSITE; PS51214; IBB; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR005673};
KW Reference proteome {ECO:0000313|Proteomes:UP000220158};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT DOMAIN 1..52
FT /note="IBB"
FT /evidence="ECO:0000259|PROSITE:PS51214"
FT REPEAT 133..176
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 176..204
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 218..246
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT REPEAT 260..302
FT /note="ARM"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
SQ SEQUENCE 544 AA; 60970 MW; D6C3610F242E624F CRC64;
MDRRIEARRK EFKKNCDDTR RKREDLVVQI RKQQRECQLE SKRAMIMANT GFEDNSYNLN
YLKTNQDDST NESICNTSSN NSSNTLEMLK KIPTLAIGVR SSEYVTQLNS TRELRKLLSI
EKGPPIQEVI NSGVVPYIVE FLKYDDKTDL QFEAAWVLTN IASGSQEQTK VVIDNNAVPY
LVRLLNSEKE DVCEQAVWAL GNIAGDSAEC REYVLNQNSL PLLLKILRTS HKRTLIRNAA
WTLSNLCRGK PAPNFEIVSK ALPTLAALIY NDDEEILTDA CWTLSYLSDG SNENINAVLD
AGVAERVVEL LSHCSFLVQT PALRTVGNIV TGDDLQTDVV VKLGAVQKLS CLLNSSKKSI
KKEACWALSN ITAGNISQIQ AVIDNNVIPQ LINILMKEDF EVRKEAAWAI SNASSGGSES
QIEYLVECGA IHSLSNLLDV EDANIISVTL EGLENILEMG ENKKLRDNLP ANPYVHLFEE
CDSVHKIDAL QDRKVDNICN KAWKILYKYF PFVINNELNN APLPLNNVFT NSDDAVLNKD
FTFD
//
