ID   A0A1J1HFX8_9DIPT        Unreviewed;       554 AA.
AC   A0A1J1HFX8;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE            EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN   ORFNames=CLUMA_CG000595 {ECO:0000313|EMBL:CRK86763.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK86763.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRK86763.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC       {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR   EMBL; CVRI01000002; CRK86763.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1HFX8; -.
DR   STRING; 568069.A0A1J1HFX8; -.
DR   OrthoDB; 3109291at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0052689; F:carboxylic ester hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   InterPro; IPR019826; Carboxylesterase_B_AS.
DR   InterPro; IPR019819; Carboxylesterase_B_CS.
DR   PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR   PANTHER; PTHR43142:SF1; CARBOXYLIC ESTER HYDROLASE; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR   PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Serine esterase {ECO:0000256|ARBA:ARBA00022487};
KW   Signal {ECO:0000256|RuleBase:RU361235}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT   CHAIN           17..554
FT                   /note="Carboxylic ester hydrolase"
FT                   /evidence="ECO:0000256|RuleBase:RU361235"
FT                   /id="PRO_5011832511"
FT   DOMAIN          19..529
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
SQ   SEQUENCE   554 AA;  62007 MW;  26E54E0DC92D954D CRC64;
     MLKLCLLLSL FVAVYGQSRP IVTTTGGQVQ GMELSTGLLQ PNFFAFKGIP FAEPPVGNLR
     FRNPVPHRGW SGVLDGAEHR PICPSTGWFG LEIGGEEDCL FLNVYTPSLS GNRAVMVWIH
     GGAFTGGSGD SWIYGPDFLV NDGVVVVTFN YRLGVLGFLA TGDTAAQGNY AMKDMVEALR
     WVRNNIARFG GNPNAITVFG ESAGGVAVHY LMLSQMGLNL FQRAISQSGT ALNPWAFQPN
     PRAQAENLGR KLGISWSSTQ NLVDQLRARP FQQLVDAQSG WADLEVPRGL TSFEWAPNVE
     PANSLEPRFL TNDPATLMRS GNFLQLPAII GYTDVESLFM VHEDRIDNTA MGQFATNPYF
     YVPRSFNLNP LTQQTQVNQV AQTFRSIYFN GQHPHQGIVF NYTQFMTDHH FTFGIDRTVR
     YHAPRQTQPI YYYKFSMDGS LNMIKRLLFL PDFPGAVHAD DLFHLFQVAS FPVPILPGNI
     ALTVRRRMVR MWVNFALTGN PTPVTDSLIT ARWERYTNAN QEFMDIGENL IPSRVPHGGR
     LEPWHNFQNQ FAPW
//