ID   A0A1J1HT97_9DIPT        Unreviewed;       549 AA.
AC   A0A1J1HT97;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   03-MAY-2023, entry version 19.
DE   SubName: Full=CLUMA_CG004966, isoform A {ECO:0000313|EMBL:CRK91288.1};
GN   ORFNames=CLUMA_CG004966 {ECO:0000313|EMBL:CRK91288.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK91288.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRK91288.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC41A transporter family.
CC       {ECO:0000256|ARBA:ARBA00009749}.
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DR   EMBL; CVRI01000020; CRK91288.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1HT97; -.
DR   OrthoDB; 5124745at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.10.357.20; SLC41 divalent cation transporters, integral membrane domain; 2.
DR   InterPro; IPR006667; SLC41_membr_dom.
DR   InterPro; IPR036739; SLC41_membr_dom_sf.
DR   InterPro; IPR045349; SLC41A1-3.
DR   PANTHER; PTHR16228:SF26; AGAP000663-PA; 1.
DR   PANTHER; PTHR16228; DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41; 1.
DR   Pfam; PF01769; MgtE; 2.
DR   SUPFAM; SSF161093; MgtE membrane domain-like; 2.
PE   3: Inferred from homology;
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        121..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        193..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        233..260
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        272..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        303..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        337..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        424..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        497..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          156..290
FT                   /note="SLC41A/MgtE integral membrane"
FT                   /evidence="ECO:0000259|Pfam:PF01769"
FT   DOMAIN          370..512
FT                   /note="SLC41A/MgtE integral membrane"
FT                   /evidence="ECO:0000259|Pfam:PF01769"
FT   REGION          1..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   549 AA;  59428 MW;  CD781E5F8E81EE6A CRC64;
     MTNINMINEL NNNSIFNGNS KKKELPDSII DAKTDTGSIP GQYKSDDKYE PYTIYGNPGN
     DDKLNALPQS TTGSLSSITT TSLASEPGGG GSGDEDGKGD KRETVGMTTE KWWQTTIQVS
     IPFFLAGIGT IGAGIILGIV ETWEVFTAIP ELFILVPALL GLKGNLDMCL ASRLSTQANL
     GNMESKKELL HMVVGNISLV QVQATVAAFI VSVFSVSVGI LTTEPAFSWD HAFLLTASAM
     FTATTSCFVL DFVLVAVIIL TTKFNVNPDN MATPLAASIG DVVTIALLSF ITSVLFVNMK
     THIWVTYVVI GTYFVILPFW VILVLRNRYT RPVLKSGWVP VLSALMISGL SGLVLQRAQD
     DFSGFVVFSP IINGIGGNLV SVQASKISTM LYQSSLPGII PPFTKIVEYP WRTLFYGTPY
     ANTARILILM SIPGQVLFIY VADFIHHLGN VTIGAPFVFS YLTASLIQVL TLLYIAHVLV
     HGLWRFKVDP DTASIPYLTA LGDFLGSSLL LGAFAFLRAI GHEYEGRDRE TADLLTTTSE
     FLLNAVGGI
//