ID   A0A1J1HU48_9DIPT        Unreviewed;      1119 AA.
AC   A0A1J1HU48;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=CLUMA_CG004770, isoform A {ECO:0000313|EMBL:CRK91082.1};
GN   ORFNames=CLUMA_CG004770 {ECO:0000313|EMBL:CRK91082.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK91082.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRK91082.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CVRI01000020; CRK91082.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1HU48; -.
DR   STRING; 568069.A0A1J1HU48; -.
DR   OrthoDB; 2911539at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   Gene3D; 6.10.140.270; -; 1.
DR   Gene3D; 1.10.220.100; conserved c-terminal region of ge- 1; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR045152; EDC4-like.
DR   InterPro; IPR049404; EDC4_C.
DR   InterPro; IPR044938; EDC4_C_sf.
DR   InterPro; IPR032401; EDC4_WD40.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR15598; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR   PANTHER; PTHR15598:SF5; ENHANCER OF MRNA-DECAPPING PROTEIN 4; 1.
DR   Pfam; PF21289; EDC4_C; 1.
DR   Pfam; PF16529; Ge1_WD40; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT   DOMAIN          35..359
FT                   /note="Enhancer of mRNA-decapping protein 4 WD40 repeat
FT                   region"
FT                   /evidence="ECO:0000259|Pfam:PF16529"
FT   DOMAIN          987..1105
FT                   /note="Enhancer of mRNA-decapping protein 4 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21289"
FT   REGION          579..605
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          651..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        579..601
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        652..675
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        681..700
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1119 AA;  126037 MW;  A2674288D024B2AD CRC64;
     MTIAFNNADD VQHCYETNGA NVVVQVQPRS GFSHGSSMVK LKNIIGYKWE KKDYPGHLIA
     IHKDGKVIAY SINVNGQGMV RLIHFGMGNK RALIKGMSKE VLDLQFADYS KEIIIGCIEE
     SALHINRLDV VDGGDSLNCT QLLKIENPIE GHVPIMDKIS WCPYVPEEND TIDEFSVMLL
     VWVRGNKFEC YSIKTIIDNY NTGVIQAENI TEGLVRSYDN QRALITHATY SPDGTTLAIS
     TIDGFIKFFQ IYFHETIPRC LHAWKPHDGA AISSFFFLDN HTQPIAGSTL WKYAVTLAAN
     NTEIKVSKCD NWKTLQTITF KSSIGQPLAF KAEIDRTSSY LILSDMTNRQ MYVLQILKEN
     ALSQQNGSEE HHNNGDDVAA NAVGGISRVF VKSIAEFRLA STILSYGISN ASIRRYKCAL
     SDNYLIDELE DYDEENNSLY CVVLRLFMIL PESVQECHIL YQPALNESAE ILNTEVKDSK
     LNIAASSSID TKKAEPLTLM TPPQKTSQIN LLTPDSFSSP VVEKQQKDVS QDVLSTIFML
     AKTNQAGTTP GVANKSHENV LNLTNVSLIE EEKIFQQKLP VDGNSNQTTT QAKSGAASGG
     SSPSREVRDI LLQADSVNED YYPGEESDDL EIEEEQNKDV LNALNALDVD FKNIDDDDDD
     DEDDGNEEDD EDDEPIVTVK PTKSTPHSDW PKAPQFMDTN SVPATSKQVE TLSTRMNQMI
     EIMETQSRYI AELRNEIYDL KASNVAEAMV IDHKLDTVEE QCKKTIEQNF VKFENSLMMK
     DKREITESIM QLFQQLSRTQ LNGIETAVKE NLLKVCTHKG FIESISHSML IGIQNSLEQT
     FRKSLEEIMI PSYEKITHEM FQEMGKAFTT GTKEYTRAFD NYMKQYGAVQ FQMTEFSGAI
     HQIPQQVRAT TEQSVLPMLN SGFVDIRQRL EKFQSKVIND VKEQVRNEIQ NGFERQTMTL
     EDSVLSVVQR SQAETPAPTI YDQRENIKQL LAHDQIDKAF HQALISSDLS LLEFTLENAD
     YQAAFNPCPL QQSVLLSLIQ QLTADMGKFS ELKLRYLSDA VLALNIYDVI TKEHAPKILR
     ELNNTLNAFT AANPKYAFNS NLRMITFAAE SKIKSNPNI
//