ID   A0A1J1I2N7_9DIPT        Unreviewed;      1290 AA.
AC   A0A1J1I2N7;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=CLUMA_CG006613, isoform A {ECO:0000313|EMBL:CRK93118.1};
GN   ORFNames=CLUMA_CG006613 {ECO:0000313|EMBL:CRK93118.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK93118.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRK93118.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CVRI01000036; CRK93118.1; -; Genomic_DNA.
DR   OrthoDB; 3144081at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   GO; GO:0005549; F:odorant binding; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 2.
DR   Gene3D; 1.10.238.20; Pheromone/general odorant binding protein domain; 6.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013818; Lipase.
DR   InterPro; IPR006170; PBP/GOBP.
DR   InterPro; IPR036728; PBP_GOBP_sf.
DR   InterPro; IPR000734; TAG_lipase.
DR   PANTHER; PTHR11610; LIPASE; 1.
DR   Pfam; PF00151; Lipase; 2.
DR   Pfam; PF01395; PBP_GOBP; 6.
DR   SMART; SM00708; PhBP; 5.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
DR   SUPFAM; SSF47565; Insect pheromone/odorant-binding proteins; 6.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..1290
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012610924"
FT   DOMAIN          37..283
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
FT   DOMAIN          349..539
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
SQ   SEQUENCE   1290 AA;  145550 MW;  A8E1305710905EC6 CRC64;
     MIMTRVFIIL VSVLKLCESS GIKNLIKFEF ISDNYSTQSY TVDNLYTILQ NPKFDRQKQT
     AIYSYGFTQT VYQPSVRKIV EAYLANSDFN FILVNYNSIL AYNIINANNF GVYIASSLEK
     LFNNGYGNFH VIGFSLGAQI SGAIGRSLIK ISKGRHIIPR ITGLDPGQIP PFFGGVIRNL
     NAGDALFVDI IHGESKFFGS PMSVGNVSFW INGGYSQPSC TSHNIIISSI CSHLMTPQYW
     AASVQGKNYQ MFPAYKCSNY YDFKFGRCDK TPVAYMGLYV DQNLNGKFYL DAKINIYKFS
     RFLLLFIELI KARFNKELHF CNKLIVKMFL KGFISALLLG ALFCDSVSGQ AEDIRFRFYF
     GANQWQFYDI TNIQTIVSHP SFSSARNTVF YHYGFTQTEN TDTVRDVINS YLQVGNVNIV
     LIYYTSVTTN AITNARELGG ALADCYIRLA DNGFPISRLH LVGFSLGAQI QAFASRNVQG
     RTNNRLVVGR LTGLDPGQIQ APLIPLVGRL SSSDAAFVDS VHTEGVGFGD HQSIGHISFA
     LTVFGIFAVA SAMPFTEEQK QKAQNYIEKC IQETGVSPEI VQKLKAGDFS NEEEKTQNFA
     LCFFREAGFV DDQGNQQLDV IIEKLSAGND TEQAKAVVEK CKDVTGTTPS RRFNKSCISC
     EKDTLRIIFD HEVHFWNIFG VRWSQVITEY FYLFQALTEE QKLKVDEHTK ICAEEVGLEY
     ESGVKYRFSV IEDNTDSAKK FVKCFFIRTG FMNEDGVLQK DVMLEKISLG KDDEAKAKIS
     AVIENCTALS VLSLFSLIAA FQKDEIKEAQ DRHSFLTKIT KECTEETGLS LDDAQKLLLG
     DLSLKTNEAM CFVRCIFQRE GFLDTADEPQ VGYIAESLAE SSKLNRKALL KILKKCSSFK
     YKDPCESAFK GSPNTLATKL EEFRIAFQGH IQHCAQEIGV TKDVVLRMTI GDFSVNDQKT
     QCFVGCFFKR MKFCVAVFLV SVAFSTVAGQ IIRRFTVRQA TRQCIAETGI SYDTAVKFSK
     GDFSEDTESA KCFLKCFAYK IKFVSPEGEF QKEELLKYVN LVASDSIPAG EIIDTCKNDT
     KRETDECDFI FRAYKCFWDG VRASEANAAR FSIYNTFEFD RLQDENETIP NEMKVLAIII
     LCFTLSISAQ THKKSIAFKA IRKCAKEHEI DYLSASNFIK GDFSKANQAT KCFLKCVAND
     MEFWINEKPQ KTNMMNYVDL LVKNSDGVSD IIDSCIENDV SDDFCEHLYN VYKCFWSKAI
     VPTNQKLQLE KEFHAENLND NELKKEASQS
//