ID A0A1J1I4I3_9DIPT Unreviewed; 575 AA.
AC A0A1J1I4I3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=CLUMA_CG008005, isoform A {ECO:0000313|EMBL:CRK94500.1};
GN Name=putative Inhibin beta chain {ECO:0000313|EMBL:CRK94500.1};
GN ORFNames=CLUMA_CG008005 {ECO:0000313|EMBL:CRK94500.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK94500.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRK94500.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; CVRI01000039; CRK94500.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1I4I3; -.
DR STRING; 568069.A0A1J1I4I3; -.
DR OrthoDB; 3015718at2759; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd13752; TGF_beta_INHB; 1.
DR Gene3D; 2.60.120.970; -; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF292; INHIBIN BETA CHAIN; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 475..575
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT COILED 64..102
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 575 AA; 66552 MW; E25174D9D1E7B493 CRC64;
MEQIYNTRSI MQKLIECNYS VINNKTASLR WIIFCALSLI NAVSCSEKLF TKDECENNPM
QLLQNEKLLN FQKLENELLE KRKELDAQLH ILYLENQKLE RVLNDNIDFI TNIDSQLEHD
VPSYCVNCIG ESFEGKSKNS LSSEYSRDRK DEFDSYMQSA EDQTPQLSDH KRLESIKHQI
LLKLGLKNKP NISTSIPKQL IFDALQRSSG LSGNLKDNLT YKSTNHRDHF QTLEKSVDTR
DRGDDNKEFM ESLTEDDQEV DDFYGHTREI ITFGERGSSV NGHHLIEFST SIDKQADLKL
SSLKIREATL WIMVETSNTV PWHNRKQRKD FLKLNQMYLE KSFDFSTYAN VPLIKNTKMK
NIVKKRKRKK REKSGIRFVN IRNNSANHIN FDNHNDDHII KNSYNKSIKR KLNQVNLAFD
KSFNYTSDSH EMKPTIWVFS IKSNDFNGAV PDQEFDENAH LIVSKTIAVR GVGWQKIDIT
SQALGWDDWI IAPLGYYANY CSGSCGGSLS RSPDTFLTYY SHVFHEVRKY NKLNGNQLCC
APLKFSSMSL IYLGPDSRVI KRDLPKMVVD ECGCP
//
