ID   A0A1J1ID56_9DIPT        Unreviewed;      1032 AA.
AC   A0A1J1ID56;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   13-SEP-2023, entry version 15.
DE   SubName: Full=CLUMA_CG011515, isoform A {ECO:0000313|EMBL:CRK98147.1};
GN   ORFNames=CLUMA_CG011515 {ECO:0000313|EMBL:CRK98147.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK98147.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRK98147.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the SLC12A transporter family.
CC       {ECO:0000256|ARBA:ARBA00010593}.
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DR   EMBL; CVRI01000047; CRK98147.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1ID56; -.
DR   STRING; 568069.A0A1J1ID56; -.
DR   OrthoDB; 5490251at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR004841; AA-permease/SLC12A_dom.
DR   InterPro; IPR018491; SLC12_C.
DR   InterPro; IPR002443; SLC12A1/SLC12A2.
DR   InterPro; IPR004842; SLC12A_fam.
DR   NCBIfam; TIGR00930; 2a30; 1.
DR   PANTHER; PTHR11827:SF48; GH09711P; 1.
DR   PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR   Pfam; PF00324; AA_permease; 1.
DR   Pfam; PF03522; SLC12; 1.
DR   PRINTS; PR01207; NAKCLTRNSPRT.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        114..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        145..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        239..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        265..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        425..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        479..499
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        505..523
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        535..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          117..616
FT                   /note="Amino acid permease/ SLC12A"
FT                   /evidence="ECO:0000259|Pfam:PF00324"
FT   DOMAIN          625..1032
FT                   /note="SLC12A transporter C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03522"
SQ   SEQUENCE   1032 AA;  114775 MW;  08E00972F54D60AE CRC64;
     MKGFTNPVDT IDEESNNPRV EKLSREISIN VTDLNYLRRN SRSVPNLNEA RRFSVNLAQL
     TREVLPRLDN YRKSVGAAQR PSLGELHGDS QRKSEAINHV DHTPKGHGHF KLGWIQGVLI
     PVLLNIYGVM LFLRMGWILG QAGIIETLII ISISAIVCLI TTLSLSAIST NGEVQGGGIY
     YIISRSLGPE FGASVGVVFA FANAVAASMN TIGFCDSLNG LLHSYGIKII DNGVNDTRII
     GTIALIIMIV ICAVGMEWEV KAQNVLVLVI AAAIINFLAG VILGPSNSED ISKGFVGFSS
     EVFLSNLKQD YRFSEGLNQN FFTVFAIFFP SVTGIQAGAN ISGDLKDPAK SIPKGTLLAL
     LISMATYLIF VFFVGGAALR DGSGIAAEVI NHNMPYNFSC IANQTCEYGI QNSFSVMQLM
     SVSSSLIYVG CFAATLSTAL TNLLSVPRLV QALGVDKIYP GVIYFSKGYG KNAEPYRGYV
     LTFIISVVFL LIADLNAVAP LISNFYLAAY ALINFCTFHA AFVKPLGWRP SFRFYNAWLS
     LFGFLLCVTI MFMLSWVSSL ITFTIIFALY LLVMYRKPDV NWGSSTQEQT YKTALSAALR
     LQRLRDHIKN YHPQVLVLAG SPHTRPPLID LGNLITKHHS LLIVGDVHED KLSHKARIEL
     IGEAQKWFDA RKIKAFYNLV DNVDFENGVR SLVQSSGFGK LSPNVVLMGF KTDWKSSSSS
     KLKTYFEALH NAFDCRMSVA ILCLPHGIDF SDYCPQYKTA GMKHSPSENF SLGAQSTEEF
     TIKPQKFMYT NSNLNIEGMD TSSNHSTVCP QSVPLPALNN ISLCDLSYAT RGGTSMTKDV
     QDAMNFFQDK QPKGTIDVWW LYDDGGLTML LPYIISTRSA WANCKIRIFA LTNRKQELVV
     EEKNMANLLS KLRIEYACLT MLQGVTEQPR DETINMHKRI IDGFMEGQNE DIFISFKEYR
     ELQQKTNLQL RLREMLLEHS RNASLIVMSL PMPKQDHVSA PLYMSWIDML TLDMPPFLLV
     RGNQSSVLTF YS
//