ID A0A1J1IDK7_9DIPT Unreviewed; 757 AA.
AC A0A1J1IDK7;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=CLUMA_CG011218, isoform A {ECO:0000313|EMBL:CRK97842.1};
GN Name=putative Cullin-2 {ECO:0000313|EMBL:CRK97842.1};
GN ORFNames=CLUMA_CG011218 {ECO:0000313|EMBL:CRK97842.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK97842.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRK97842.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; CVRI01000047; CRK97842.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1IDK7; -.
DR STRING; 568069.A0A1J1IDK7; -.
DR OrthoDB; 5474206at2759; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF177; CULLIN-2; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 402..621
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 757 AA; 87953 MW; B7E4C1F5788F8739 CRC64;
MSLKPRRILF DEVWGCLKTT VEKVITLRAV KKDKWNDSFN DVYSICVAYP EPLADRLYTE
TKLFLENHVK SQLDDFGVYM MEVNDTDNSQ NQLLHKYYSA WKNYSEGLGF LNSLYSYLNQ
QHIKKQKVSE AEILYGNGGH LSVAQEQMEI GELGLDIWRI FMIQNLGDIL VKQILQGIER
DRVESNLSSK DIETLNGVIH SFVMVQDYKK KGNLKLYENM FEGKMLEASG EYFKSQASKL
LQTCSVSQYM QEVIRILDEE NIRAHKFMHI SSIQKLKKEC EDRMITDHKY FLYSECKDMV
SNDKRDDLKN LYTLLKPIVD GLKELIQFLL EQIKNEGTES VMNLKGENIH IQFVENMLQV
HQKYENLISE TFKNDPLFLS ALDKACASVI NSKLCDGKTA CRSAELVAKY HDSLLKKSKS
TESEIETKLT KSITIFKYIE DKDVYQKFYS RMLAKRLIHD QSVNMELEEV MINKLKQACG
YEFTNKLHRM YTDVGISMDL NNKFNQHLKN QNNELHINLS IKILQAGAWP LGPQTAIPFA
VPQEFEKPIR DFETFYNLKF SGRKLSWLHH LCHGELKVSL AKKSYLITMQ TYQMAMLLLF
ENCDTLSCKD IKDVLQLNNN ENFQKHLQSL IDSKLLTVDT EKIEESSIVS FNLDFSNKRT
KFKITASLQK ESPQQEVEQT HTQVDEDRKL YLQAAIVRIM KSRKVLKHNA LIQEILSQSK
VSFAPSIPMI KKCIESLIDK QYIERTANSS DEYSYVA
//
