ID   A0A1J1IE36_9DIPT        Unreviewed;       554 AA.
AC   A0A1J1IE36;
DT   15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT   15-FEB-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=CLUMA_CG011829, isoform A {ECO:0000313|EMBL:CRK98472.1};
GN   Name=similar to FERM {ECO:0000313|EMBL:CRK98472.1};
GN   ORFNames=CLUMA_CG011829 {ECO:0000313|EMBL:CRK98472.1};
OS   Clunio marinus.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC   Clunio.
OX   NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK98472.1, ECO:0000313|Proteomes:UP000183832};
RN   [1] {ECO:0000313|EMBL:CRK98472.1, ECO:0000313|Proteomes:UP000183832}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Syromyatnikov M.Y., Popov V.N.;
RL   Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell junction, adherens junction
CC       {ECO:0000256|ARBA:ARBA00004536}. Cell projection, rhabdomere
CC       {ECO:0000256|ARBA:ARBA00043944}.
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DR   EMBL; CVRI01000047; CRK98472.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1J1IE36; -.
DR   STRING; 568069.A0A1J1IE36; -.
DR   OrthoDB; 2876516at2759; -.
DR   Proteomes; UP000183832; Unassembled WGS sequence.
DR   GO; GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.
DR   GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0009887; P:animal organ morphogenesis; IEA:UniProt.
DR   GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR   CDD; cd14473; FERM_B-lobe; 1.
DR   CDD; cd13193; FERM_C_FARP1-like; 1.
DR   CDD; cd17098; FERM_F1_FARP1_like; 1.
DR   Gene3D; 1.20.80.10; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR019749; Band_41_domain.
DR   InterPro; IPR000798; Ez/rad/moesin-like.
DR   InterPro; IPR014847; FA.
DR   InterPro; IPR041788; FARP1/FARP2/FRMD7_FERM_C.
DR   InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR   InterPro; IPR035963; FERM_2.
DR   InterPro; IPR019748; FERM_central.
DR   InterPro; IPR019747; FERM_CS.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR45858; FERM DOMAIN CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR45858:SF5; MOESIN_EZRIN_RADIXIN HOMOLOG 1; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF00373; FERM_M; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   PRINTS; PR00935; BAND41.
DR   PRINTS; PR00661; ERMFAMILY.
DR   SMART; SM00295; B41; 1.
DR   SMART; SM01195; FA; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF47031; Second domain of FERM; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS00660; FERM_1; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000183832}.
FT   DOMAIN          44..329
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   REGION          1..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          390..436
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..38
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        398..419
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   554 AA;  62190 MW;  1BF0A7D8F6462B92 CRC64;
     MSLNSLGATN GHPSSRMTHS LSTPSGVDGS TSTSHHSRGG GKKLAVRVQM LDDSVTMFQV
     QAKALGKVLF EQVCRQLNLL EADYFGLEYH ESSTGTKYWL DLEKPLNRQV GFSLVDPMLK
     FCVKFYAPDP AQLEEEYTRY LFCLQVKRDL ATGSLQCNDN TAALMASYIV QASCGDYSYE
     DYPDHTYLSS YRFVPQQDHT MQRRIMENHK KHVGQSPAEA DLNLLETARR CELYGMKMHA
     AKDHEGVPLN LAVAHMGIAV FQGITRINTF SWAKIRKISF KRKKLLIKLH PEGYGYYKDI
     VEFFFEGRNE CKNFWKKCVE NHGFFRCQAV QSIPRRKTRV LSRGSSFRYS GKTQKQIIEF
     VRDNYVKRQT FQSSGLGSSQ TTEPRIEDAF SDEEGSGYGD SPTRNSYPIQ PSSGHGSTGG
     DLSDDEDIGA APTSPQRTIG FESLCITNGG DYSPTQHQQQ CARSRSGSCA SRRSQLSQFR
     SEPPLCHYPQ IYSSQQFIHH PLSTAPTLGG SQQFYGGDRG IFDQSREYCP TPGYFTPLHP
     NGSINGSQCH VNPL
//