ID A0A1J1II65_9DIPT Unreviewed; 289 AA.
AC A0A1J1II65;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=CLUMA_CG013191, isoform A {ECO:0000313|EMBL:CRK99888.1};
GN Name=putative Spermidine synthase {ECO:0000313|EMBL:CRK99888.1};
GN ORFNames=CLUMA_CG013191 {ECO:0000313|EMBL:CRK99888.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK99888.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRK99888.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the spermidine/spermine synthase family.
CC {ECO:0000256|ARBA:ARBA00007867, ECO:0000256|RuleBase:RU003836}.
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DR EMBL; CVRI01000054; CRK99888.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1II65; -.
DR STRING; 568069.A0A1J1II65; -.
DR OrthoDB; 1126121at2759; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006596; P:polyamine biosynthetic process; IEA:UniProtKB-UniRule.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.30.140.10; Spermidine synthase, tetramerisation domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR HAMAP; MF_00198; Spermidine_synth; 1.
DR InterPro; IPR030374; PABS.
DR InterPro; IPR030373; PABS_CS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR001045; Spermi_synthase.
DR InterPro; IPR035246; Spermidine_synt_N.
DR InterPro; IPR037163; Spermidine_synt_N_sf.
DR NCBIfam; TIGR00417; speE; 1.
DR PANTHER; PTHR11558:SF11; SPERMIDINE SYNTHASE; 1.
DR PANTHER; PTHR11558; SPERMIDINE/SPERMINE SYNTHASE; 1.
DR Pfam; PF17284; Spermine_synt_N; 1.
DR Pfam; PF01564; Spermine_synth; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS01330; PABS_1; 1.
DR PROSITE; PS51006; PABS_2; 1.
PE 3: Inferred from homology;
KW Polyamine biosynthesis {ECO:0000256|PROSITE-ProRule:PRU00354};
KW Reference proteome {ECO:0000313|Proteomes:UP000183832};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU00354}.
FT DOMAIN 6..242
FT /note="PABS"
FT /evidence="ECO:0000259|PROSITE:PS51006"
FT ACT_SITE 162
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00354"
SQ SEQUENCE 289 AA; 32504 MW; 255D32EACA32D3E7 CRC64;
MNTLVKGWFS EISDELWPGQ CFSLKVKEIL HEEKSEFQDI KILDTETYGK ALILDGVIQC
TERDEFGYQE LISMIPICSH PNPERVLIVG GGDGGVAREA IKHPAVKEVY QVEIDGRVVD
LSKKYLPFMA CGFDSPKVHL TIGDGFEFMK NHKEEFDVII TDSSDPIGPA VSLFQESYFE
LMKKALRPGG IICSQGSNFW IDLEHVKETL KACACHFKNT SYAMAMVPSY PCGSIGFVIG
CLDEKRDLKT PLHCFTTDQI DKLNFKYYTS DVHKGAFALP RFAAKAFEF
//
