ID A0A1J1IMU3_9DIPT Unreviewed; 934 AA.
AC A0A1J1IMU3;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=CLUMA_CG013101, isoform A {ECO:0000313|EMBL:CRK99793.1};
GN ORFNames=CLUMA_CG013101 {ECO:0000313|EMBL:CRK99793.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRK99793.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRK99793.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CVRI01000053; CRK99793.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1IMU3; -.
DR STRING; 568069.A0A1J1IMU3; -.
DR OrthoDB; 22856at2759; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01817; RBD1_RGS12_like; 1.
DR CDD; cd17067; RBD2_RGS12_like; 1.
DR Gene3D; 1.10.196.10; -; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003109; GoLoco_motif.
DR InterPro; IPR003116; RBD_dom.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR046995; RGS10/12/14-like.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR024066; RGS_subdom1/3.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR45945; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR PANTHER; PTHR45945:SF3; REGULATOR OF G-PROTEIN SIGNALING LOCO; 1.
DR Pfam; PF02196; RBD; 1.
DR Pfam; PF00615; RGS; 1.
DR PRINTS; PR01301; RGSPROTEIN.
DR SMART; SM00390; GoLoco; 1.
DR SMART; SM00455; RBD; 2.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
DR PROSITE; PS50877; GOLOCO; 1.
DR PROSITE; PS50898; RBD; 2.
DR PROSITE; PS50132; RGS; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000183832}.
FT DOMAIN 118..234
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 353..423
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT DOMAIN 424..494
FT /note="RBD"
FT /evidence="ECO:0000259|PROSITE:PS50898"
FT REGION 61..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 265..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..809
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 867..934
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..304
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..330
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 884..900
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 913..934
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 934 AA; 105331 MW; 0034D5A9C2D76065 CRC64;
MPNYNYYKTI SANMLVTTHD LNFVMGFIKE DEIYNPQNGS KQIPNELSPF KRWGQSSLRS
RVDPRTPLQR RPSSLAASES DVYIKTNHND QDDDEDDNEK NEKEVVVYPT GPTVWGQSFE
LLLNDPAGLH AFSEFLKKEF SGENIYFWTA CERYRQINDV SERTKEALAI FDKHLANGSL
EPVNVDSQAR LRAQERLISA EKDLFIQVQK QILNLMKFDS YQRFIRSDLY KTCLDAESRN
LPLPYPAEQL DPMLRITINQ PSNVSTKLKK SLSNAEDRRR KSLLPWHRKT RCKSKDRDES
SKETMKNSTS SSNTLKQHSN HSAGDIHSSR SSLSSFDATI SKINSFDDDT RSSLCRVILS
NGATTIVQTR ANETIRELVE RLLDKRGITY HAYEAFLSGT NKPLDLDGLS TQLSGNEVMI
EQRVVFKLDL PNKKVISVKS KICKVLSEVL RPILHKYNYR LDLVQVYGKE SSDPLDMSLP
VTAVDGQRLQ IICREENPEL AGEVTSINTN GKHQKFKFAN GPITFVKANK LTMSASNPQL
NTLDEITNKV FNELLQGKVD GQGIVNGFNG NGDERGSVKS EDWGSETSSG IFNRMRRHPK
KSQKMISKSS AGSEEGDVNG IKKPLIAKWK AGAKLQVTSR AQNDESLLEG LKRAQRSRLE
DQRGTEINFE LPEFLKDKEK YANVGNKLRK TKFDESPSNS ISLYNNIDKC NNNNDPVVKM
NSSAPQKPPQ PAPRLSLTGK SPTKLTAEVS SSVQSKISSL ENAIMLNSPN GSAKMFPTQR
DEAPNEMNVS TQCLPSNTPI KTRDSSSYYS PDGSSGIYAD TTMVFNHQSN SGYESSKDIM
GYYNNNNHHD YQEIEDANRN RIFKHDEEQQ KVPPLPPKPS KLPIKPSNWQ TTSNNKENFF
KSPHELPRRA PLASAETSST KNDVYLDQPT SSFV
//
