ID A0A1J1IPZ1_9DIPT Unreviewed; 761 AA.
AC A0A1J1IPZ1;
DT 15-FEB-2017, integrated into UniProtKB/TrEMBL.
DT 15-FEB-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE RecName: Full=serine--tRNA ligase {ECO:0000256|ARBA:ARBA00012840};
DE EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
GN Name=putative Serine--tRNA ligase {ECO:0000313|EMBL:CRL02307.1};
GN ORFNames=CLUMA_CG015368 {ECO:0000313|EMBL:CRL02307.1};
OS Clunio marinus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Chironomoidea; Chironomidae;
OC Clunio.
OX NCBI_TaxID=568069 {ECO:0000313|EMBL:CRL02307.1, ECO:0000313|Proteomes:UP000183832};
RN [1] {ECO:0000313|EMBL:CRL02307.1, ECO:0000313|Proteomes:UP000183832}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Syromyatnikov M.Y., Popov V.N.;
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC Type-1 seryl-tRNA synthetase subfamily.
CC {ECO:0000256|ARBA:ARBA00010728}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CVRI01000057; CRL02307.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1J1IPZ1; -.
DR STRING; 568069.A0A1J1IPZ1; -.
DR OrthoDB; 239638at2759; -.
DR Proteomes; UP000183832; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR CDD; cd01824; Phospholipase_B_like; 1.
DR Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR InterPro; IPR002314; aa-tRNA-synt_IIb.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR001087; GDSL.
DR InterPro; IPR035547; Phospholipase_B.
DR InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR InterPro; IPR036514; SGNH_hydro_sf.
DR NCBIfam; TIGR00414; serS; 1.
DR PANTHER; PTHR11778:SF7; SERINE--TRNA LIGASE, CYTOPLASMIC-RELATED; 1.
DR PANTHER; PTHR11778; SERYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00657; Lipase_GDSL; 1.
DR Pfam; PF00587; tRNA-synt_2b; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF52266; SGNH hydrolase; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000183832}.
FT DOMAIN 496..729
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
SQ SEQUENCE 761 AA; 87796 MW; F47583F7E2AA1968 CRC64;
MSEVIKFQYK NYRTLFFTLI KNQIPSEAHK INLKLGRLQP QLTQNESFFC DTTTIPKKSK
NIPQSVHELR PGDIDIVGAI GDSLTAGNGG MATNIFQVTI ESKGVSFSIG GEKTWREYLT
IPNILKEFNP NVYGYSVGDG LTIFKSSKFN AAELGAMSRD TPYMARVLIN RIKTDPNVKP
YHWKLITFLI GSNDFCLDFC HRQHPEEKVN EHERDLLNVF RTIRDNLNRT MLNVVLPPNM
KVLVNFKGKP EQCEFMHKFE CPCYFGSNRK KNHEKYFKIA EEWNKRVIEV ANRDEFHDRK
DFTINVQPFV RNFVFPTLSN GLHDFTYMSM DCFHLSQKGY AMAFSTLVTK RQEPTEVKSH
KFSLSTPVYD EKFLLDEKNI ENINENIKLR KGVGDIFKVH ELRNNLKCQN LSHEENIKLN
LQLQEEFKRI PNNTHPDVKH YGDHPKVIGY YNKKPEFNHK PLDFADICKA FNILRTEHMG
NFSGSKSYIL MKELAELEQA LIRYTLEEIL KHGFRLMSVP DILPSEVIKS CGMTTDGERN
QVYRLLPSNL CLSGTSEMAL AGYFAGNKLK EKELPVKVAA VSRCFRAESS SVLEERGIFR
VHQFTKVEMF SVCRPSESPL ILDEFKEIEI NLFKNIGIHF QLLDMPPSEL GAPAYRKYDI
EAWMPGRNMW GEISSCSNCT DYQSRRLNIK VEESDEFAHT VNGTACAIPR MLIAIIESFQ
HEDGTVLIPK VLQKYMRCEK IMKNKTLPKL KLIKSLTSEK S
//
